HRP20110138T1 - Kultura staničnog medija bez seruma za stanice sisavaca - Google Patents
Kultura staničnog medija bez seruma za stanice sisavaca Download PDFInfo
- Publication number
- HRP20110138T1 HRP20110138T1 HR20110138T HRP20110138T HRP20110138T1 HR P20110138 T1 HRP20110138 T1 HR P20110138T1 HR 20110138 T HR20110138 T HR 20110138T HR P20110138 T HRP20110138 T HR P20110138T HR P20110138 T1 HRP20110138 T1 HR P20110138T1
- Authority
- HR
- Croatia
- Prior art keywords
- process according
- growth hormone
- medium
- concentration
- medium contains
- Prior art date
Links
- 239000006143 cell culture medium Substances 0.000 title claims abstract 3
- 210000004962 mammalian cell Anatomy 0.000 title 1
- 238000000034 method Methods 0.000 claims abstract 16
- 239000002609 medium Substances 0.000 claims abstract 13
- 102000018997 Growth Hormone Human genes 0.000 claims abstract 12
- 108010051696 Growth Hormone Proteins 0.000 claims abstract 12
- 239000000122 growth hormone Substances 0.000 claims abstract 12
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract 5
- 239000011701 zinc Substances 0.000 claims abstract 5
- 229910052725 zinc Inorganic materials 0.000 claims abstract 5
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract 4
- 229910052802 copper Inorganic materials 0.000 claims abstract 4
- 239000010949 copper Substances 0.000 claims abstract 4
- 241001465754 Metazoa Species 0.000 claims abstract 2
- 210000002966 serum Anatomy 0.000 claims abstract 2
- DIGQNXIGRZPYDK-WKSCXVIASA-N (2R)-6-amino-2-[[2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-[[(2R,3S)-2-[[2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S,3S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[2-[[2-[[2-[(2-amino-1-hydroxyethylidene)amino]-3-carboxy-1-hydroxypropylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxypropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1,5-dihydroxy-5-iminopentylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxybutylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1,3-dihydroxypropylidene]amino]-1-hydroxyethylidene]amino]-1-hydroxy-3-sulfanylpropylidene]amino]-1-hydroxyethylidene]amino]hexanoic acid Chemical compound C[C@@H]([C@@H](C(=N[C@@H](CS)C(=N[C@@H](C)C(=N[C@@H](CO)C(=NCC(=N[C@@H](CCC(=N)O)C(=NC(CS)C(=N[C@H]([C@H](C)O)C(=N[C@H](CS)C(=N[C@H](CO)C(=NCC(=N[C@H](CS)C(=NCC(=N[C@H](CCCCN)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C([C@H](CS)N=C([C@H](CO)N=C([C@H](CO)N=C([C@H](C)N=C(CN=C([C@H](CO)N=C([C@H](CS)N=C(CN=C(C(CS)N=C(C(CC(=O)O)N=C(CN)O)O)O)O)O)O)O)O)O)O)O)O DIGQNXIGRZPYDK-WKSCXVIASA-N 0.000 claims 3
- 108090000157 Metallothionein Proteins 0.000 claims 3
- 102000003792 Metallothionein Human genes 0.000 claims 3
- 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 claims 2
- 102000002265 Human Growth Hormone Human genes 0.000 claims 2
- 108010000521 Human Growth Hormone Proteins 0.000 claims 2
- 239000000854 Human Growth Hormone Substances 0.000 claims 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- 229910052742 iron Inorganic materials 0.000 claims 2
- -1 iron ions Chemical class 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 241001529936 Murinae Species 0.000 claims 1
- 101000969137 Mus musculus Metallothionein-1 Proteins 0.000 claims 1
- 238000004113 cell culture Methods 0.000 claims 1
- 229910000365 copper sulfate Inorganic materials 0.000 claims 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- MVFCKEFYUDZOCX-UHFFFAOYSA-N iron(2+);dinitrate Chemical compound [Fe+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O MVFCKEFYUDZOCX-UHFFFAOYSA-N 0.000 claims 1
- NPFOYSMITVOQOS-UHFFFAOYSA-K iron(III) citrate Chemical compound [Fe+3].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NPFOYSMITVOQOS-UHFFFAOYSA-K 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims 1
- 229910000368 zinc sulfate Inorganic materials 0.000 claims 1
- 229960001763 zinc sulfate Drugs 0.000 claims 1
- CWYNVVGOOAEACU-UHFFFAOYSA-N Fe2+ Chemical compound [Fe+2] CWYNVVGOOAEACU-UHFFFAOYSA-N 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 229910001448 ferrous ion Inorganic materials 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04105451 | 2004-11-02 | ||
| US62488504P | 2004-11-04 | 2004-11-04 | |
| PCT/EP2005/055637 WO2006108455A1 (en) | 2004-11-02 | 2005-10-28 | Serum-free cell culture medium for mammalian cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20110138T1 true HRP20110138T1 (hr) | 2011-04-30 |
Family
ID=39560946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20110138T HRP20110138T1 (hr) | 2004-11-02 | 2011-02-24 | Kultura staničnog medija bez seruma za stanice sisavaca |
Country Status (8)
| Country | Link |
|---|---|
| BR (1) | BRPI0517942B8 (ru) |
| CY (1) | CY1111412T1 (ru) |
| EA (1) | EA011749B1 (ru) |
| HK (1) | HK1106791A1 (ru) |
| HR (1) | HRP20110138T1 (ru) |
| IL (1) | IL182602A (ru) |
| MX (1) | MX2007005210A (ru) |
| NZ (1) | NZ554131A (ru) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2473556C1 (ru) * | 2011-07-14 | 2013-01-27 | Закрытое акционерное общество "ГЕНЕРИУМ" | Промышленный способ получения и очистки рекомбинантного гормона роста человека из телец включения |
| EP2768944B2 (en) * | 2011-10-21 | 2023-11-22 | Pfizer Inc. | Addition of iron to improve cell culture |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CS262822B1 (en) * | 1986-10-03 | 1989-04-14 | Kovar Jan | Synthetic medium for the cultivation of myelomic cells |
| US6048728A (en) * | 1988-09-23 | 2000-04-11 | Chiron Corporation | Cell culture medium for enhanced cell growth, culture longevity, and product expression |
| US5143842A (en) * | 1988-11-01 | 1992-09-01 | The University Of Colorado Foundation, Inc. | Media for normal human muscle satellite cells |
| NO894143D0 (no) * | 1988-11-18 | 1989-10-17 | Phillips Petroleum Co | Bovinmetallotionein-regulatorisk omraade. |
| US5834312A (en) * | 1990-01-29 | 1998-11-10 | Hy-Gene, Inc. | Process and media for the growth of human epithelia |
| US5122469A (en) * | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| GB9022545D0 (en) * | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
| EP2243827B2 (en) * | 1996-08-30 | 2017-11-22 | Life Technologies Corporation | Serum-free mammalian cell culture medium, and uses thereof |
| ATE399855T1 (de) * | 1996-10-10 | 2008-07-15 | Invitrogen Corp | Tierzellkulturmedium mit pflanzlichen nährstoffen |
-
2005
- 2005-10-28 BR BRPI0517942A patent/BRPI0517942B8/pt active IP Right Grant
- 2005-10-28 NZ NZ554131A patent/NZ554131A/en unknown
- 2005-10-28 MX MX2007005210A patent/MX2007005210A/es active IP Right Grant
- 2005-10-28 EA EA200701000A patent/EA011749B1/ru not_active IP Right Cessation
-
2007
- 2007-04-17 IL IL182602A patent/IL182602A/en active IP Right Grant
-
2008
- 2008-01-10 HK HK08100349.0A patent/HK1106791A1/xx unknown
-
2011
- 2011-02-24 HR HR20110138T patent/HRP20110138T1/hr unknown
- 2011-03-03 CY CY20111100252T patent/CY1111412T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2007005210A (es) | 2007-05-11 |
| NZ554131A (en) | 2009-08-28 |
| EA011749B1 (ru) | 2009-06-30 |
| BRPI0517942A (pt) | 2008-10-21 |
| HK1106791A1 (en) | 2008-03-20 |
| CY1111412T1 (el) | 2015-08-05 |
| BRPI0517942B8 (pt) | 2021-05-25 |
| EA200701000A1 (ru) | 2007-10-26 |
| IL182602A0 (en) | 2007-07-24 |
| BRPI0517942B1 (pt) | 2019-04-02 |
| IL182602A (en) | 2013-07-31 |
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