HK14287A - Antibacterial composition of thienamycin type compound and a dipeptidase inhibitor - Google Patents

Antibacterial composition of thienamycin type compound and a dipeptidase inhibitor

Info

Publication number
HK14287A
HK14287A HK14287A HK14287A HK14287A HK 14287 A HK14287 A HK 14287A HK 14287 A HK14287 A HK 14287A HK 14287 A HK14287 A HK 14287A HK 14287 A HK14287 A HK 14287A
Authority
HK
Hong Kong
Prior art keywords
type compound
antibacterial composition
dipeptidase inhibitor
thienamycin
thienamycin type
Prior art date
Application number
HK14287A
Other languages
English (en)
Inventor
Helmut Kropp
Frederick M Kahan
Donald W Graham
Edward F Rogers
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of HK14287A publication Critical patent/HK14287A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK14287A 1980-09-17 1987-02-19 Antibacterial composition of thienamycin type compound and a dipeptidase inhibitor HK14287A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18817880A 1980-09-17 1980-09-17
US18792980A 1980-09-17 1980-09-17

Publications (1)

Publication Number Publication Date
HK14287A true HK14287A (en) 1987-02-27

Family

ID=26883552

Family Applications (1)

Application Number Title Priority Date Filing Date
HK14287A HK14287A (en) 1980-09-17 1987-02-19 Antibacterial composition of thienamycin type compound and a dipeptidase inhibitor

Country Status (4)

Country Link
EP (1) EP0048025B1 (xx)
DE (2) DE48025T1 (xx)
HK (1) HK14287A (xx)
SG (1) SG87986G (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880793A (en) * 1978-07-24 1989-11-14 Merck & Co., Inc. Combination of thienamycin-type antibiotics with dipeptidase inhibitors
US5202467A (en) * 1990-02-08 1993-04-13 Sumitomo Chemical Company, Limited Process for preparing haloketo acid derivatives
US5268501A (en) * 1990-02-08 1993-12-07 Sumitomo Chemical Company, Limited Process for preparing haloketo acid derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ190994A (en) * 1978-07-24 1981-10-19 Merck & Co Inc Z-2-acylamino-3-monosubstituted propenoates
AR244550A1 (es) * 1978-07-24 1993-11-30 Merck & Co Inc Procedimiento para obtener una composicion de antibioticos del tipo de la tienamicina con inhibidores de la dipeptidasa
IE50333B1 (en) * 1979-11-02 1986-04-02 Merck & Co Inc Antibacterial compositions comprising a beta-lactam-type compound and a 3-substituted propenoate

Also Published As

Publication number Publication date
EP0048025A1 (en) 1982-03-24
EP0048025B1 (en) 1986-01-15
SG87986G (en) 1987-03-27
DE3173503D1 (en) 1986-02-27
DE48025T1 (de) 1983-03-17

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Legal Events

Date Code Title Description
PE Patent expired