HK1258026A1 - 預防和治療角膜混濁和瘢痕的組合物和方法 - Google Patents

預防和治療角膜混濁和瘢痕的組合物和方法

Info

Publication number
HK1258026A1
HK1258026A1 HK19100397.8A HK19100397A HK1258026A1 HK 1258026 A1 HK1258026 A1 HK 1258026A1 HK 19100397 A HK19100397 A HK 19100397A HK 1258026 A1 HK1258026 A1 HK 1258026A1
Authority
HK
Hong Kong
Prior art keywords
scarring
prevention
compositions
treatment
methods
Prior art date
Application number
HK19100397.8A
Other languages
English (en)
Inventor
Sunil Chauhan
Reza Dana
Original Assignee
Schepens Eye Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schepens Eye Res Inst filed Critical Schepens Eye Res Inst
Publication of HK1258026A1 publication Critical patent/HK1258026A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
HK19100397.8A 2015-09-11 2019-01-10 預防和治療角膜混濁和瘢痕的組合物和方法 HK1258026A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562217611P 2015-09-11 2015-09-11
PCT/US2016/050945 WO2017044743A1 (en) 2015-09-11 2016-09-09 Compositions and methods for prevention and treatment of corneal haze and scarring

Publications (1)

Publication Number Publication Date
HK1258026A1 true HK1258026A1 (zh) 2019-11-01

Family

ID=58240852

Family Applications (1)

Application Number Title Priority Date Filing Date
HK19100397.8A HK1258026A1 (zh) 2015-09-11 2019-01-10 預防和治療角膜混濁和瘢痕的組合物和方法

Country Status (7)

Country Link
US (4) US10449234B2 (zh)
EP (2) EP3347034B1 (zh)
JP (3) JP6929273B2 (zh)
AU (2) AU2016320905B2 (zh)
CA (1) CA2999511C (zh)
HK (1) HK1258026A1 (zh)
WO (1) WO2017044743A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10449234B2 (en) 2015-09-11 2019-10-22 The Schepens Eye Research Institute, Inc. Compositions and methods for prevention and treatment of corneal haze and scarring
US11845952B2 (en) * 2018-02-07 2023-12-19 Nippon Medical School Foundation Adeno-associated virus vector
CA3115773A1 (en) * 2018-10-09 2020-04-16 Jennifer COCHRAN Engineered fibroblast growth factor variants combined with engineered hepatocyte growth factor variants for treatment
EP3934623A4 (en) * 2019-03-08 2022-11-23 University of Pittsburgh - Of the Commonwealth System of Higher Education MULTI-LAYER DRUG DELIVERY COATING FOR CONTACT LENSES
EP3962511A4 (en) * 2019-04-29 2023-01-18 The Board of Trustees of the Leland Stanford Junior University METHOD OF EYE TREATMENT USING AN ENGINEERED DIMERIC HEPATOCYTE GROWTH FACTOR FRAGMENT
WO2022241465A1 (en) 2021-05-14 2022-11-17 Claris Biotherapeutics, Inc. Compositions of growth factor for the treatment of eye disease

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5589451A (en) 1992-09-21 1996-12-31 Board Of Regents, The University Of Texas System Methods and treaments for corneal healing with hepatocyte and keratinocyte growth factors
US5703047A (en) * 1992-09-21 1997-12-30 Board Of Regents, The University Of Texas System Methods and treatments for corneal healing with growth factors
JP3962097B2 (ja) * 1994-03-18 2007-08-22 敏一 中村 免疫抑制剤による副作用の軽減剤
DE69925578T2 (de) 1998-03-05 2006-04-27 Senju Pharmaceutical Co., Ltd. Pharmazeutische zusammenstellung zur vorbeugung und behandlung von mit zellkrankheiten des augenhintergrundes zusammenhängenden krankheiten
US8575099B2 (en) * 2006-04-20 2013-11-05 Osaka University Agent for treating polyglutamine aggregation-caused disease or suppressing onset thereof
WO2007122975A1 (ja) * 2006-04-20 2007-11-01 Kringle Pharma Inc. Ｈｇｆ前駆体蛋白質改変体及びその活性型蛋白質
US20070167935A1 (en) 2007-01-19 2007-07-19 Serdarevic Olivia N Methods and compositions for optimizing the outcomes of refractive laser surgery of the cornea
US9556248B2 (en) * 2010-03-19 2017-01-31 The Board Of Trustees Of The Leland Stanford Junior University Hepatocyte growth factor fragments that function as potent met receptor agonists and antagonists
BR112013023458B1 (pt) 2011-03-14 2020-04-07 Drug Delivery Solutions Ltd composição oftálmica, e, método para fabricar a composição oftálmica
US8999938B2 (en) 2013-06-21 2015-04-07 Gnt Llc Ophthalmic lipophilic drug delivery vehicle formulations
US10449234B2 (en) 2015-09-11 2019-10-22 The Schepens Eye Research Institute, Inc. Compositions and methods for prevention and treatment of corneal haze and scarring

Also Published As

Publication number Publication date
EP3347034C0 (en) 2024-05-29
US10449234B2 (en) 2019-10-22
JP2021181472A (ja) 2021-11-25
CA2999511C (en) 2024-01-23
US20210299219A1 (en) 2021-09-30
EP3347034A4 (en) 2019-05-08
EP3347034B1 (en) 2024-05-29
US11759499B2 (en) 2023-09-19
CA2999511A1 (en) 2017-03-16
AU2016320905B2 (en) 2021-10-07
EP4417259A2 (en) 2024-08-21
US20200121758A1 (en) 2020-04-23
WO2017044743A1 (en) 2017-03-16
US20180256685A1 (en) 2018-09-13
JP2023179739A (ja) 2023-12-19
JP6929273B2 (ja) 2021-09-01
EP4417259A3 (en) 2024-10-23
EP3347034A1 (en) 2018-07-18
US20240123032A1 (en) 2024-04-18
JP2018526412A (ja) 2018-09-13
AU2021286438A1 (en) 2022-01-20
AU2016320905A1 (en) 2018-04-05

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