HK1257686A1 - 用於匹配腫瘤學特徵的系統和方法 - Google Patents

用於匹配腫瘤學特徵的系統和方法

Info

Publication number
HK1257686A1
HK1257686A1 HK19100052.4A HK19100052A HK1257686A1 HK 1257686 A1 HK1257686 A1 HK 1257686A1 HK 19100052 A HK19100052 A HK 19100052A HK 1257686 A1 HK1257686 A1 HK 1257686A1
Authority
HK
Hong Kong
Prior art keywords
oncology
signatures
matching
systems
methods
Prior art date
Application number
HK19100052.4A
Other languages
English (en)
Inventor
Andrea Califano
Mariano Javier Alvarez
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of HK1257686A1 publication Critical patent/HK1257686A1/zh

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Evolutionary Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
HK19100052.4A 2015-08-28 2019-01-03 用於匹配腫瘤學特徵的系統和方法 HK1257686A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562211562P 2015-08-28 2015-08-28
US201562253342P 2015-11-10 2015-11-10
PCT/US2016/049063 WO2017040311A1 (en) 2015-08-28 2016-08-26 Systems and methods for matching oncology signatures

Publications (1)

Publication Number Publication Date
HK1257686A1 true HK1257686A1 (zh) 2019-10-25

Family

ID=58103455

Family Applications (1)

Application Number Title Priority Date Filing Date
HK19100052.4A HK1257686A1 (zh) 2015-08-28 2019-01-03 用於匹配腫瘤學特徵的系統和方法

Country Status (6)

Country Link
US (2) US10777299B2 (zh)
EP (1) EP3340996B1 (zh)
CN (1) CN108348547B (zh)
ES (1) ES2913294T3 (zh)
HK (1) HK1257686A1 (zh)
WO (1) WO2017040311A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108351915B (zh) 2015-08-28 2022-09-09 纽约市哥伦比亚大学信托人 通过调节子富集测定进行的蛋白质活性的虚拟推断
CN109658984B (zh) * 2018-12-18 2021-12-03 北京深度制耀科技有限公司 一种信息推荐和信息推荐模型训练方法、相关装置
CN109949268A (zh) * 2019-01-24 2019-06-28 郑州大学第一附属医院 一种基于机器学习的肝细胞癌分化水平分级方法
EP3946339A1 (en) 2019-03-27 2022-02-09 Karyopharm Therapeutics Inc. Biomarkers for selinexor
GB201905181D0 (en) * 2019-04-11 2019-05-29 Arrayjet Ltd Method and apparatus for substrate handling and printing
WO2021163338A1 (en) 2020-02-11 2021-08-19 Karyopharm Therapeutics Inc. Xpo1 inhibitors for use in treating cancer
WO2021252900A1 (en) 2020-06-11 2021-12-16 Karyopharm Therapeutics Inc. Biomarkers for response to exportin-1 inhibitors in multiple myeloma patients
WO2021252905A1 (en) 2020-06-11 2021-12-16 Karyopharm Therapeutics Inc. Biomarkers for response to exportin-1 inhibitors in diffuse large b-cell lymphoma patients
CN113249326A (zh) * 2021-04-19 2021-08-13 佛山市第一人民医院（中山大学附属佛山医院） 一种筛选肿瘤抗原特异性tcr序列的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000054046A2 (en) 1999-03-10 2000-09-14 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, The National Institutes Of Health Universal protein array system
EP1545507A4 (en) * 2002-07-17 2009-04-22 Arqule Inc THERAPY BY ACTIVATION OF ACTIVATED CONTROL POINTS AND METHODS OF USE
US8497292B2 (en) * 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
WO2009092024A1 (en) 2008-01-16 2009-07-23 The Trustees Of Columbia University In The City Of New York System and method for prediction of phenotypically relevant genes and perturbation targets
JP2012510813A (ja) * 2008-12-05 2012-05-17 ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション 卵巣癌の診断および治療のためのマイクロｒｎａに基づく方法および組成物
WO2011028819A1 (en) 2009-09-01 2011-03-10 The Trustees Of Columbia University In The City Of New York Synergistic transcription modules and uses thereof
US20130144584A1 (en) 2011-12-03 2013-06-06 Medeolinx, LLC Network modeling for drug toxicity prediction
US9690844B2 (en) 2014-01-24 2017-06-27 Samsung Electronics Co., Ltd. Methods and systems for customizable clustering of sub-networks for bioinformatics and health care applications
WO2015127104A1 (en) * 2014-02-19 2015-08-27 The Trustees Of Columbia University In The City Of New York Method and Composition for Diagnosis or Treatment of Aggressive Prostate Cancer

Also Published As

Publication number Publication date
EP3340996A4 (en) 2019-06-12
WO2017040311A1 (en) 2017-03-09
CN108348547B (zh) 2023-09-22
EP3340996A1 (en) 2018-07-04
US20210257044A1 (en) 2021-08-19
CN108348547A (zh) 2018-07-31
US10777299B2 (en) 2020-09-15
EP3340996B1 (en) 2022-02-23
ES2913294T3 (es) 2022-06-01
US20170056530A1 (en) 2017-03-02

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