HK1257549A1 - 用 cmp 活化吡喃壬酮糖酸類似化合物治療和預防奈瑟氏淋病球菌感染 - Google Patents

用 cmp 活化吡喃壬酮糖酸類似化合物治療和預防奈瑟氏淋病球菌感染

Info

Publication number
HK1257549A1
HK1257549A1 HK18116510.7A HK18116510A HK1257549A1 HK 1257549 A1 HK1257549 A1 HK 1257549A1 HK 18116510 A HK18116510 A HK 18116510A HK 1257549 A1 HK1257549 A1 HK 1257549A1
Authority
HK
Hong Kong
Prior art keywords
nonulosonate
cmp
prevention
activated
treatment
Prior art date
Application number
HK18116510.7A
Other languages
English (en)
Inventor
Ian C Schoenhofen
Original Assignee
Nat Res Council Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Council Canada filed Critical Nat Res Council Canada
Publication of HK1257549A1 publication Critical patent/HK1257549A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012—Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18116510.7A 2015-08-19 2018-12-24 用 cmp 活化吡喃壬酮糖酸類似化合物治療和預防奈瑟氏淋病球菌感染 HK1257549A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562207246P 2015-08-19 2015-08-19
PCT/CA2016/050977 WO2017027980A1 (en) 2015-08-19 2016-08-19 Treatment and prevention of neisseria gonorrhoeae infection using cmp-activated nonulosonate analog compounds

Publications (1)

Publication Number Publication Date
HK1257549A1 true HK1257549A1 (zh) 2019-10-25

Family

ID=58050504

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18116510.7A HK1257549A1 (zh) 2015-08-19 2018-12-24 用 cmp 活化吡喃壬酮糖酸類似化合物治療和預防奈瑟氏淋病球菌感染

Country Status (6)

Country Link
US (2) US20180235989A1 (zh)
EP (1) EP3337488A4 (zh)
CN (1) CN108348537B (zh)
CA (1) CA2995863A1 (zh)
HK (1) HK1257549A1 (zh)
WO (1) WO2017027980A1 (zh)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374532A (en) * 1992-08-31 1994-12-20 The Biomembrane Institute Method for determining susceptibility to escherichia coli urinary tract infections and method for diagnosing secretors and nonsecretors
EP0957107B1 (en) * 1996-05-16 2004-07-21 Nissin Food Products Co., Ltd. Novel compounds having antiviral activity
ES2554172T3 (es) * 2008-12-16 2015-12-16 National Research Council Of Canada Biosíntesis de ácido CMP-legionamínico a partir de fructosa-6-P
CA2760106C (en) * 2009-05-04 2020-03-10 National Research Council Of Canada Inhibitors of sialidase or sialidase-like enzymes
CA2796284C (en) * 2010-04-20 2022-05-31 National Research Council Of Canada Cell-based production of nonulosonates
CA3207636A1 (en) * 2014-02-20 2015-08-20 National Research Council Of Canada Neisseria gonorrhoeae therapeutic based on cmp-nonulosonate sugar

Also Published As

Publication number Publication date
EP3337488A4 (en) 2019-03-20
CA2995863A1 (en) 2017-02-23
EP3337488A1 (en) 2018-06-27
US20180235989A1 (en) 2018-08-23
CN108348537B (zh) 2021-11-05
US20210401863A1 (en) 2021-12-30
CN108348537A (zh) 2018-07-31
WO2017027980A1 (en) 2017-02-23

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