HK1254168A1 - 用於治療皰疹病毒誘導的病況的方法和組合物 - Google Patents

用於治療皰疹病毒誘導的病況的方法和組合物

Info

Publication number
HK1254168A1
HK1254168A1 HK18113305.3A HK18113305A HK1254168A1 HK 1254168 A1 HK1254168 A1 HK 1254168A1 HK 18113305 A HK18113305 A HK 18113305A HK 1254168 A1 HK1254168 A1 HK 1254168A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
induced conditions
treating herpesvirus
herpesvirus induced
Prior art date
Application number
HK18113305.3A
Other languages
English (en)
Inventor
Douglas V Faller
Original Assignee
Univ Boston
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Boston filed Critical Univ Boston
Publication of HK1254168A1 publication Critical patent/HK1254168A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18113305.3A 2015-06-19 2018-10-17 用於治療皰疹病毒誘導的病況的方法和組合物 HK1254168A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562182071P 2015-06-19 2015-06-19
PCT/US2016/038148 WO2016205695A1 (en) 2015-06-19 2016-06-17 Methods and compositions for treating herpesvirus induced conditions

Publications (1)

Publication Number Publication Date
HK1254168A1 true HK1254168A1 (zh) 2019-07-12

Family

ID=57546411

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18113305.3A HK1254168A1 (zh) 2015-06-19 2018-10-17 用於治療皰疹病毒誘導的病況的方法和組合物

Country Status (6)

Country Link
US (3) US20180185345A1 (zh)
EP (1) EP3310168B1 (zh)
JP (2) JP7366385B2 (zh)
CN (2) CN108347929A (zh)
HK (1) HK1254168A1 (zh)
WO (1) WO2016205695A1 (zh)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI794171B (zh) 2016-05-11 2023-03-01 美商滬亞生物國際有限公司 Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療
TWI808055B (zh) 2016-05-11 2023-07-11 美商滬亞生物國際有限公司 Hdac 抑制劑與 pd-1 抑制劑之組合治療
EA202090764A1 (ru) * 2017-12-08 2020-08-03 Борис Славинович ФАРБЕР Фармацевтическая композиция для элиминации возбудителей герпесвирусных инфекций из тканей макроорганизма
JP7194458B2 (ja) 2018-07-19 2022-12-22 国立大学法人大阪大学 ウイルス計測方法、ウイルス計測装置、およびストレス判定装置
JP2022536256A (ja) * 2019-05-31 2022-08-15 ヴィラクタ サブシディアリー，インク． ヒストンデアセチラーゼ阻害剤を用いてウイルス関連癌を治療する方法
WO2020243326A1 (en) * 2019-05-31 2020-12-03 Viracta Therapeutics, Inc. Methods of treating virally associated cancers with histone deacetylase inhibitors
CN114306313B (zh) * 2019-07-18 2023-06-16 北京市农林科学院 克拉屈滨在抑制犬细小病毒中的应用
CN112294810B (zh) * 2019-07-29 2024-03-01 深圳微芯生物科技股份有限公司 含有西达本胺和表面活性剂的药物组合物
CN112569243A (zh) * 2019-09-30 2021-03-30 神农医药科技有限公司 制备治疗阿尔茨海默病的药物
JP2022552642A (ja) * 2019-10-07 2022-12-19 ヴィラクタ サブシディアリー，インク． 副作用が軽減されたｈｄａｃ治療の調剤
CN111187751A (zh) * 2020-01-19 2020-05-22 中国农业科学院兰州兽医研究所 一种用于构建幼畜心肌炎细胞模型的细胞系及构建方法
CN112111006B (zh) * 2020-08-27 2022-06-07 北京弘进久安生物科技有限公司 抗牛结节性皮肤病病毒的抗体、检测试纸及试剂盒
EP4232076A1 (en) * 2020-10-20 2023-08-30 The Chancellor, Masters and Scholars of The University of Oxford Methods and compositions for treating epstein barr virus-associated cancer
CN112877275B (zh) * 2021-02-04 2023-03-31 中国农业科学院兰州兽医研究所 Hdac2基因敲除的bhk-21细胞系及其构建方法和应用
CN112980878B (zh) * 2021-02-04 2023-03-31 中国农业科学院兰州兽医研究所 Hdac8基因敲除的bhk-21细胞系及其构建方法和应用
WO2023244968A1 (en) * 2022-06-13 2023-12-21 Viracta Subsidiary, Inc. Methods of treating autoimmune disorders with histone deacetylase inhibitors
WO2024112712A1 (en) * 2022-11-21 2024-05-30 Henderson Theodore Treatment using an antiviral compound and spironolactone

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US4747825A (en) 1984-06-29 1988-05-31 Ferring Laboratories, Inc. Apparatus and methodology for pulsed administration of growth promoting agents
US4948592A (en) 1986-05-09 1990-08-14 Alza Corporation Pulsed drug delivery
US4723958A (en) 1986-05-23 1988-02-09 Merck & Co., Inc. Pulsatile drug delivery system
US4965251A (en) 1987-04-03 1990-10-23 The Board Of Regents Of The University Of Washington Pulse treatment of hemoglobinopathies with erythropoietin
US5766573A (en) 1988-12-06 1998-06-16 Riker Laboratories, Inc. Medicinal aerosol formulations
US5190029A (en) 1991-02-14 1993-03-02 Virginia Commonwealth University Formulation for delivery of drugs by metered dose inhalers with reduced or no chlorofluorocarbon content
US5376359A (en) 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
US5403590A (en) 1992-12-21 1995-04-04 New England Deaconess Hospital Corporation Method of pulsatile drug infusion
US20110086869A1 (en) * 2009-09-24 2011-04-14 The Trustees Of Boston University Methods for treating viral disorders
WO2011113013A2 (en) * 2010-03-11 2011-09-15 Hemaquest Pharmaceuticals, Inc. Methods and compositions for treating viral or virally-induced conditions
MX365393B (es) * 2011-09-13 2019-05-31 Pharmacyclics Llc Formulaciones de inhibidor de histona deacetilasa en combinación con bendamustina y usos de las mismas.
WO2014074952A1 (en) * 2012-11-09 2014-05-15 Massachusetts Institute Of Technology Methods and compositions for localized delivery of agents to hiv-infected cells and tissues
CN104083763A (zh) * 2014-07-16 2014-10-08 中国人民解放军军事医学科学院野战输血研究所 组蛋白去乙酰化酶抑制剂在制备潜伏病毒激活剂中的应用

Also Published As

Publication number Publication date
EP3310168B1 (en) 2024-08-21
JP2022058416A (ja) 2022-04-12
JP7366385B2 (ja) 2023-10-23
US20240041848A1 (en) 2024-02-08
CN108347929A (zh) 2018-07-31
CN116712552A (zh) 2023-09-08
US20180185345A1 (en) 2018-07-05
WO2016205695A1 (en) 2016-12-22
EP3310168A4 (en) 2019-03-06
JP2018517757A (ja) 2018-07-05
US20210046061A1 (en) 2021-02-18
EP3310168A1 (en) 2018-04-25

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