HK1252105A1 - 包含編碼類m蛋白質的mrna的癌症疫苗 - Google Patents

包含編碼類m蛋白質的mrna的癌症疫苗

Info

Publication number
HK1252105A1
HK1252105A1 HK18111425.2A HK18111425A HK1252105A1 HK 1252105 A1 HK1252105 A1 HK 1252105A1 HK 18111425 A HK18111425 A HK 18111425A HK 1252105 A1 HK1252105 A1 HK 1252105A1
Authority
HK
Hong Kong
Prior art keywords
protein
mrna encoding
cancer vaccine
vaccine
cancer
Prior art date
Application number
HK18111425.2A
Other languages
English (en)
Inventor
Michael J P Lawman
Patricia D Lawman
Meghan Gentilini
Vijay Ramiya
Marina Victor Abdelmaseeh Bastawrous
Original Assignee
Morphogenesis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Morphogenesis Inc filed Critical Morphogenesis Inc
Publication of HK1252105A1 publication Critical patent/HK1252105A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
HK18111425.2A 2015-05-19 2018-09-05 包含編碼類m蛋白質的mrna的癌症疫苗 HK1252105A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562163446P 2015-05-19 2015-05-19

Publications (1)

Publication Number Publication Date
HK1252105A1 true HK1252105A1 (zh) 2019-05-17

Family

ID=56119750

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18111425.2A HK1252105A1 (zh) 2015-05-19 2018-09-05 包含編碼類m蛋白質的mrna的癌症疫苗

Country Status (9)

Country Link
US (1) US9636388B2 (zh)
EP (1) EP3297664B1 (zh)
JP (2) JP6717932B2 (zh)
CN (1) CN107847577B (zh)
AU (1) AU2016264363B2 (zh)
CA (1) CA2985087C (zh)
DK (1) DK3297664T3 (zh)
HK (1) HK1252105A1 (zh)
WO (1) WO2016187407A1 (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10682401B2 (en) 2015-05-19 2020-06-16 Morphogenesis, Inc. Multi-indication mRNA cancer immunotherapy
DK3297664T3 (da) * 2015-05-19 2020-12-07 Morphogenesis Inc Cancervaccine omfattende mrna, der koder for et m-lignende protein
RU2769316C2 (ru) 2016-05-18 2022-03-30 МОДЕРНАТиЭкс, ИНК. Полинуклеотиды, кодирующие интерлейкин-12 (il12), и их применения
US11649288B2 (en) 2017-02-07 2023-05-16 Seattle Children's Hospital Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
WO2018160622A1 (en) 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy
WO2018204234A1 (en) * 2017-05-01 2018-11-08 Morphogenesis, Inc. Multi-indication mrna cancer immunotherapy
WO2018213731A1 (en) 2017-05-18 2018-11-22 Modernatx, Inc. Polynucleotides encoding tethered interleukin-12 (il12) polypeptides and uses thereof
US11311576B2 (en) 2018-01-22 2022-04-26 Seattle Children's Hospital Methods of use for CAR T cells
CN111699011B (zh) * 2018-02-09 2023-07-28 株式会社大赛璐 注入器
CN110856724B (zh) * 2018-08-24 2022-05-27 杭州康万达医药科技有限公司 包含核酸及car修饰的免疫细胞的治疗剂及其应用
CN110124019B (zh) 2019-04-22 2022-09-23 海南医学院 细菌化肿瘤细胞疫苗及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7795020B2 (en) 1998-01-14 2010-09-14 Morphogenesis, Inc. Tumor cell vaccines
WO1999036433A2 (en) 1998-01-14 1999-07-22 Morphogenesis, Inc. Materials and methods for treating oncological disease
US7348015B2 (en) 1998-01-14 2008-03-25 Morphogenesis, Inc. Antigen modified cancer cell vaccines for cancer therapy
EP2742951B1 (en) * 2004-09-14 2016-02-03 Argos Therapeutics, Inc. Strain independent amplification of HIV polynucleotides
CA2925658C (en) * 2013-10-01 2022-12-06 Mie University Long chain antigen containing interepitope sequence that promotes antigen presentation to t cells
WO2015134577A1 (en) 2014-03-06 2015-09-11 Morphogenesis, Inc. Dna vector and transformed tumor cell vaccines
DK3297664T3 (da) * 2015-05-19 2020-12-07 Morphogenesis Inc Cancervaccine omfattende mrna, der koder for et m-lignende protein

Also Published As

Publication number Publication date
JP6717932B2 (ja) 2020-07-08
AU2016264363B2 (en) 2019-07-25
US9636388B2 (en) 2017-05-02
JP2020169185A (ja) 2020-10-15
CN107847577B (zh) 2021-11-23
CN107847577A (zh) 2018-03-27
JP2018521115A (ja) 2018-08-02
CA2985087C (en) 2021-02-16
CA2985087A1 (en) 2016-11-24
WO2016187407A1 (en) 2016-11-24
EP3297664B1 (en) 2020-11-18
US20170042993A1 (en) 2017-02-16
JP7065907B2 (ja) 2022-05-12
AU2016264363A1 (en) 2018-01-04
DK3297664T3 (da) 2020-12-07
EP3297664A1 (en) 2018-03-28

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