HK1249863A1 - 包含adamts13的組合物在使梗塞中阻塞的血管再通的方法中的應用 - Google Patents

包含adamts13的組合物在使梗塞中阻塞的血管再通的方法中的應用

Info

Publication number
HK1249863A1
HK1249863A1 HK18109356.9A HK18109356A HK1249863A1 HK 1249863 A1 HK1249863 A1 HK 1249863A1 HK 18109356 A HK18109356 A HK 18109356A HK 1249863 A1 HK1249863 A1 HK 1249863A1
Authority
HK
Hong Kong
Prior art keywords
adamts13
recanalization
infarction
compositions
methods
Prior art date
Application number
HK18109356.9A
Other languages
English (en)
Inventor
Barbara Plaimauer
Hanspeter Rottensteiner
Friedrich Scheiflinger
Meyer Simon De
Frederik Denorme
Original Assignee
Baxalta Inc
Baxalta GmbH
Univ Leuven Kath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxalta Inc, Baxalta GmbH, Univ Leuven Kath filed Critical Baxalta Inc
Publication of HK1249863A1 publication Critical patent/HK1249863A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24087—ADAMTS13 endopeptidase (3.4.24.87)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HK18109356.9A 2015-05-26 2018-07-19 包含adamts13的組合物在使梗塞中阻塞的血管再通的方法中的應用 HK1249863A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562166586P 2015-05-26 2015-05-26
PCT/US2016/034353 WO2016191565A1 (en) 2015-05-26 2016-05-26 Compositions comprising adamts13 for use in methods for the recanalization of occluded blood vessels in an infarction

Publications (1)

Publication Number Publication Date
HK1249863A1 true HK1249863A1 (zh) 2018-11-16

Family

ID=53784248

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18109356.9A HK1249863A1 (zh) 2015-05-26 2018-07-19 包含adamts13的組合物在使梗塞中阻塞的血管再通的方法中的應用

Country Status (13)

Country Link
US (2) US20180110842A1 (zh)
EP (1) EP3302533A1 (zh)
JP (2) JP6877356B2 (zh)
KR (1) KR20180006376A (zh)
CN (1) CN107635577A (zh)
AU (2) AU2016268389A1 (zh)
BR (1) BR112017025142A2 (zh)
CA (1) CA2979940A1 (zh)
EA (1) EA201792130A1 (zh)
GB (1) GB201510870D0 (zh)
HK (1) HK1249863A1 (zh)
MX (1) MX2017013384A (zh)
WO (1) WO2016191565A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022019817A2 (pt) 2020-04-02 2022-12-06 Takeda Pharmaceuticals Co Variante de adamts13, composições e usos das mesmas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009539757A (ja) * 2006-06-16 2009-11-19 バクスター・インターナショナル・インコーポレイテッド 血栓溶解活性を有するａｄａｍｔｓ１３含有組成物
US8685665B2 (en) * 2007-06-22 2014-04-01 The Chemo-Sero-Therapeutic Research Institute ADAMTS-13 mutant
US20090317375A1 (en) * 2008-05-12 2009-12-24 Immune Disease Institute, Inc. Von willebrand factor (vwf) inhibitors for treatment or prevention of infarction
EA024267B1 (ru) * 2009-09-21 2016-09-30 Баксалта Инкорпорейтид Стабилизированные жидкие и лиофилизированные композиции adamts13
CN103566362B (zh) * 2012-07-21 2015-07-29 复旦大学 重组adamts13在制备脑出血药物中的用途
AU2013203062C1 (en) * 2013-03-15 2018-06-28 Takeda Pharmaceutical Company Limited Subcutaneous administration of adamts13

Also Published As

Publication number Publication date
EP3302533A1 (en) 2018-04-11
US20210128701A1 (en) 2021-05-06
WO2016191565A1 (en) 2016-12-01
AU2022203572A1 (en) 2022-06-16
CA2979940A1 (en) 2016-12-01
JP2018516855A (ja) 2018-06-28
JP6877356B2 (ja) 2021-05-26
MX2017013384A (es) 2017-12-07
EA201792130A1 (ru) 2018-04-30
BR112017025142A2 (pt) 2018-08-07
JP2021138699A (ja) 2021-09-16
AU2016268389A1 (en) 2017-09-28
KR20180006376A (ko) 2018-01-17
US20180110842A1 (en) 2018-04-26
CN107635577A (zh) 2018-01-26
GB201510870D0 (en) 2015-08-05

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