HK1245645A1 - 使用抗壞血酸穩定化放射性藥物組合物 - Google Patents

使用抗壞血酸穩定化放射性藥物組合物

Info

Publication number
HK1245645A1
HK1245645A1 HK18105069.5A HK18105069A HK1245645A1 HK 1245645 A1 HK1245645 A1 HK 1245645A1 HK 18105069 A HK18105069 A HK 18105069A HK 1245645 A1 HK1245645 A1 HK 1245645A1
Authority
HK
Hong Kong
Prior art keywords
stabilization
ascorbic acid
radiopharmaceutical compositions
radiopharmaceutical
compositions
Prior art date
Application number
HK18105069.5A
Other languages
English (en)
Inventor
James F Castner
Dianne D Zdankiewicz
James E Anderson
Original Assignee
Lantheus Medical Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42983052&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1245645(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lantheus Medical Imaging Inc filed Critical Lantheus Medical Imaging Inc
Publication of HK1245645A1 publication Critical patent/HK1245645A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/0412—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K51/0421—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0455—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18105069.5A 2009-04-15 2018-04-19 使用抗壞血酸穩定化放射性藥物組合物 HK1245645A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16935309P 2009-04-15 2009-04-15

Publications (1)

Publication Number Publication Date
HK1245645A1 true HK1245645A1 (zh) 2018-08-31

Family

ID=42983052

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18105069.5A HK1245645A1 (zh) 2009-04-15 2018-04-19 使用抗壞血酸穩定化放射性藥物組合物

Country Status (15)

Country Link
US (3) US9687571B2 (zh)
EP (1) EP2419096B1 (zh)
JP (1) JP5662416B2 (zh)
KR (2) KR101602992B1 (zh)
CN (2) CN107261159B (zh)
AU (1) AU2016201367B2 (zh)
CA (1) CA2758883C (zh)
DK (1) DK2419096T3 (zh)
ES (1) ES2770364T3 (zh)
HK (1) HK1245645A1 (zh)
IL (1) IL215823A (zh)
LT (1) LT2419096T (zh)
PT (1) PT2419096T (zh)
WO (1) WO2010120368A2 (zh)
ZA (1) ZA201108351B (zh)

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EP2419096B1 (en) 2009-04-15 2019-11-13 Lantheus Medical Imaging, Inc. Stabilization of radiopharmaceutical compositions using ascorbic acid
JP6092628B2 (ja) 2010-02-08 2017-03-08 ランセウス メディカル イメージング， インコーポレイテッド 造影剤およびその中間体を合成するための方法および装置
MX367382B (es) 2010-05-11 2019-08-19 Lantheus Medical Imaging Inc Composiciones, metodos y sistemas para la sintesis y el uso de agentes trazadores.
SG2014013767A (en) 2011-09-09 2014-05-29 Lantheus Medical Imaging Inc Compositions, methods, and systems for the synthesis and use of imaging agents
CA2852395C (en) * 2011-10-21 2020-04-28 Lantheus Medical Imaging, Inc. Compositions comprising ascorbic acid and pyridaben and pyridaben analogs attached to an imaging moiety and related methods
ES2748940T3 (es) 2011-11-11 2020-03-18 Univ Yale Evaluación de la presencia de una fibrilación auricular y de la vulnerabilidad a ésta, y otras indicaciones sobre la base de la toma de imágenes basada en metaloproteinasas de matriz
CN109125745B (zh) * 2012-04-10 2022-07-26 蓝瑟斯医学影像公司 放射性药物合成方法
AU2013203000B9 (en) 2012-08-10 2017-02-02 Lantheus Medical Imaging, Inc. Compositions, methods, and systems for the synthesis and use of imaging agents
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JPWO2020202831A1 (zh) * 2019-03-29 2020-10-08
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Also Published As

Publication number Publication date
LT2419096T (lt) 2020-04-10
ES2770364T3 (es) 2020-07-01
KR20120017427A (ko) 2012-02-28
CN107261159B (zh) 2021-01-12
WO2010120368A3 (en) 2011-02-24
CA2758883C (en) 2020-03-10
AU2010237040A1 (en) 2011-12-08
CN107261159A (zh) 2017-10-20
EP2419096A2 (en) 2012-02-22
KR101602992B1 (ko) 2016-03-11
US20120237445A1 (en) 2012-09-20
EP2419096B1 (en) 2019-11-13
US20180071411A1 (en) 2018-03-15
PT2419096T (pt) 2020-02-19
AU2016201367B2 (en) 2017-11-23
AU2016201367A1 (en) 2016-03-24
CN102458396B (zh) 2017-05-10
US20200222562A1 (en) 2020-07-16
US20130101508A9 (en) 2013-04-25
IL215823A0 (en) 2012-01-31
WO2010120368A2 (en) 2010-10-21
JP2012524064A (ja) 2012-10-11
CN102458396A (zh) 2012-05-16
US9687571B2 (en) 2017-06-27
AU2010237040B2 (en) 2015-12-03
KR20160030589A (ko) 2016-03-18
JP5662416B2 (ja) 2015-01-28
DK2419096T3 (da) 2020-02-03
IL215823A (en) 2015-10-29
EP2419096A4 (en) 2015-06-03
ZA201108351B (en) 2019-03-27
CA2758883A1 (en) 2010-10-21

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