HK1244277A1 - 新的取代的三唑並嘧啶作為抗瘧藥 - Google Patents

新的取代的三唑並嘧啶作為抗瘧藥

Info

Publication number
HK1244277A1
HK1244277A1 HK18103789.9A HK18103789A HK1244277A1 HK 1244277 A1 HK1244277 A1 HK 1244277A1 HK 18103789 A HK18103789 A HK 18103789A HK 1244277 A1 HK1244277 A1 HK 1244277A1
Authority
HK
Hong Kong
Prior art keywords
new substituted
malarial agents
substituted triazolopyrimidines
triazolopyrimidines
malarial
Prior art date
Application number
HK18103789.9A
Other languages
English (en)
Inventor
Margaret Phillips
Susan A Charman
Pradipsinh K Rathod
David Matthews
David Waterson
Original Assignee
Univ Texas
Univ Washington
Medicines For Malaria Venture Mmv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Univ Washington, Medicines For Malaria Venture Mmv filed Critical Univ Texas
Publication of HK1244277A1 publication Critical patent/HK1244277A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18103789.9A 2015-03-26 2018-03-19 新的取代的三唑並嘧啶作為抗瘧藥 HK1244277A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562138544P 2015-03-26 2015-03-26
EP15161153.0A EP3072894A1 (en) 2015-03-26 2015-03-26 New substituted triazolopyrimidines as anti-malarial agents
PCT/IB2016/051670 WO2016151521A1 (en) 2015-03-26 2016-03-24 New substituted triazolopyrimidines as anti-malarial agents

Publications (1)

Publication Number Publication Date
HK1244277A1 true HK1244277A1 (zh) 2018-08-03

Family

ID=52736971

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18103789.9A HK1244277A1 (zh) 2015-03-26 2018-03-19 新的取代的三唑並嘧啶作為抗瘧藥

Country Status (8)

Country Link
US (1) US20180065968A1 (zh)
EP (2) EP3072894A1 (zh)
JP (1) JP2018509437A (zh)
CN (1) CN107454901A (zh)
BR (1) BR112017020556A2 (zh)
CA (1) CA2980512A1 (zh)
HK (1) HK1244277A1 (zh)
WO (1) WO2016151521A1 (zh)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9216983B2 (en) * 2007-12-21 2015-12-22 Board Of Regents, University Of Texas System Dihydroorotate dehydrogenase inhibitors with selective anti-malarial activity
CN102741255B (zh) * 2009-09-29 2015-10-07 得克萨斯大学体系董事会 作为双氢乳清酸脱氢酶抑制剂的抗疟剂

Also Published As

Publication number Publication date
JP2018509437A (ja) 2018-04-05
EP3072894A1 (en) 2016-09-28
CN107454901A (zh) 2017-12-08
US20180065968A1 (en) 2018-03-08
WO2016151521A1 (en) 2016-09-29
BR112017020556A2 (pt) 2018-07-17
CA2980512A1 (en) 2016-09-29
EP3274351A1 (en) 2018-01-31

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