HK1223981A1 - 用於預測年齡和鑒別誘發或者抑制早衰試劑的方法 - Google Patents
用於預測年齡和鑒別誘發或者抑制早衰試劑的方法Info
- Publication number
- HK1223981A1 HK1223981A1 HK16111169.4A HK16111169A HK1223981A1 HK 1223981 A1 HK1223981 A1 HK 1223981A1 HK 16111169 A HK16111169 A HK 16111169A HK 1223981 A1 HK1223981 A1 HK 1223981A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- induce
- methods
- premature aging
- identifying agents
- inhibit premature
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261724528P | 2012-11-09 | 2012-11-09 | |
| PCT/US2013/069710 WO2014075083A1 (en) | 2012-11-09 | 2013-11-12 | Methods for predicting age and identifying agents that induce or inhibit premature aging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1223981A1 true HK1223981A1 (zh) | 2017-08-11 |
Family
ID=50685247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16111169.4A HK1223981A1 (zh) | 2012-11-09 | 2016-09-22 | 用於預測年齡和鑒別誘發或者抑制早衰試劑的方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10087486B2 (zh) |
| EP (1) | EP2917371A4 (zh) |
| CN (1) | CN105745333A (zh) |
| CA (1) | CA2929471C (zh) |
| HK (1) | HK1223981A1 (zh) |
| WO (1) | WO2014075083A1 (zh) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010037001A2 (en) | 2008-09-26 | 2010-04-01 | Immune Disease Institute, Inc. | Selective oxidation of 5-methylcytosine by tet-family proteins |
| US10750653B2 (en) | 2016-03-02 | 2020-08-25 | Deere & Company | Automated leveling and depth control system of a work machine and method thereof |
| US10667454B2 (en) | 2016-03-02 | 2020-06-02 | Deere & Company | Hydraulic control system of an implement for a work machine and method thereof |
| EP3464642A4 (en) | 2016-05-31 | 2020-02-19 | The Regents of the University of California | METHOD FOR EVALUATING, MONITORING AND MODULATING THE AGING PROCESS |
| WO2018109667A1 (en) | 2016-12-15 | 2018-06-21 | Nestec Sa | Compositions and methods that modulate white blood cells or neutrophils in a companion animal |
| KR101873303B1 (ko) * | 2017-01-24 | 2018-07-02 | 연세대학교 산학협력단 | 타액 내 dna 메틸화를 이용한 연령 예측 방법 |
| WO2018137203A1 (zh) * | 2017-01-25 | 2018-08-02 | 深圳华大基因研究院 | 确定人群样本生物指标集、预测生物学年龄的方法及其应用 |
| WO2018146482A1 (en) * | 2017-02-09 | 2018-08-16 | Babraham Institute | Novel age calculation method |
| EP3583229A1 (en) * | 2017-02-20 | 2019-12-25 | Deutsches Krebsforschungszentrum | Dna methylation signatures for determining a survival probability |
| CN108509769B (zh) * | 2017-03-13 | 2021-06-22 | 北京林业大学 | 确定预定物种的基因表达和甲基化修饰调控的关系的方法 |
| EP3415635B8 (en) * | 2017-06-12 | 2021-09-15 | Beiersdorf AG | Age determination of a human individual |
| US11999995B2 (en) | 2017-08-31 | 2024-06-04 | The Regents Of The University Of California | Methylome profiling in animals and uses thereof |
| CN109593862B (zh) * | 2017-09-28 | 2022-04-15 | 公安部物证鉴定中心 | 一种获得中国人群男性个体年龄的方法和系统 |
| WO2019143845A1 (en) * | 2018-01-17 | 2019-07-25 | The Regents Of The University Of California | Phenotypic age and dna methylation based biomarkers for life expectancy and morbidity |
| EP3802856A4 (en) * | 2018-05-31 | 2022-02-16 | The Regents Of The University Of California | DNA METHYLATION-BASED BIOMARKER OF AGING FOR EX VIVO AND IN VIVO HUMAN STUDIES |
| US20210207214A1 (en) * | 2018-06-15 | 2021-07-08 | Conopco, Inc.., d/b/a UNILEVER | Epigenetic method to estimate the extrinsic age of skin |
| CN112218958A (zh) * | 2018-06-15 | 2021-01-12 | 荷兰联合利华有限公司 | 估计皮肤内在年龄的表观遗传学方法 |
| WO2020076983A1 (en) * | 2018-10-10 | 2020-04-16 | The Regents Of The University Of California | Dna methylation based biomarkers for life expectancy and morbidity |
| CN111041104B (zh) * | 2018-10-11 | 2022-09-16 | 博尔诚（北京）科技有限公司 | 用于评估目标对象衰老状况以及用于评估制品抗衰老作用的组合物及其用途 |
| JP7320067B2 (ja) | 2019-01-18 | 2023-08-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 保存された遺伝子座に基づく、哺乳動物に関するｄｎａメチル化測定 |
| CN111500694B (zh) * | 2019-01-31 | 2023-02-24 | 中国科学院脑科学与智能技术卓越创新中心 | Baz2b基因作为靶点在缓解衰老中的应用 |
| US20220002809A1 (en) * | 2019-02-06 | 2022-01-06 | The Regents Of The University Of California | Dna methylation based estimator of telomere length |
| KR102170423B1 (ko) * | 2019-02-19 | 2020-10-27 | 바이오코아 주식회사 | 체액을 이용한 연령 추적 방법 |
| CN111763742A (zh) * | 2019-04-02 | 2020-10-13 | 深圳华大法医科技有限公司 | 甲基化标志物及确定个体年龄的方法和应用 |
| WO2020219957A1 (en) * | 2019-04-24 | 2020-10-29 | Massachusetts Institute Of Technology | Methods of detecting and measuring molecular aging in the brain |
| GB201908624D0 (en) | 2019-06-17 | 2019-07-31 | Vib Vzw | Predicting age using dna methylation signatures |
| FR3097560B1 (fr) * | 2019-06-24 | 2021-06-25 | Oreal | Méthode de diagnostic d’une exposition chronique à la pollution |
| WO2021030271A2 (en) | 2019-08-09 | 2021-02-18 | Nutcracker Therapeutics, Inc. | Methods and apparatuses for manufacturing for removing material from a therapeutic composition |
| US11227691B2 (en) | 2019-09-03 | 2022-01-18 | Kpn Innovations, Llc | Systems and methods for selecting an intervention based on effective age |
| CN110734485A (zh) * | 2019-09-26 | 2020-01-31 | 浙江海洋大学 | 一种曼氏无针乌贼衰老过程中的蛋白生物标志物 |
| US11250337B2 (en) | 2019-11-04 | 2022-02-15 | Kpn Innovations Llc | Systems and methods for classifying media according to user negative propensities |
| CN111139292A (zh) * | 2019-12-03 | 2020-05-12 | 河南远止生物技术有限公司 | 一种基于焦磷酸测序建立的生物学年龄推断的方法 |
| CN117467769A (zh) * | 2019-12-05 | 2024-01-30 | 圣湘生物科技股份有限公司 | 一种用于辅助诊断肝癌的试剂及其在制备试剂盒中的用途 |
| CN111477273A (zh) * | 2020-05-18 | 2020-07-31 | 中国人民解放军国防科技大学 | 一种基于脑组织基因表达预测个体年龄信息的方法 |
| WO2022051700A1 (en) * | 2020-09-04 | 2022-03-10 | Viome Life Sciences, Inc. | Biomarkers for age |
| WO2022058980A1 (en) | 2020-09-21 | 2022-03-24 | Insilico Medicine Ip Limited | Methylation data signatures of aging and methods of determining a methylation aging clock |
| KR20230083293A (ko) * | 2020-09-23 | 2023-06-09 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 어류 또는 파충류의 연령화 방법 |
| US11312989B1 (en) * | 2021-03-20 | 2022-04-26 | The Florida International University Board Of Trustees | Materials and methods for age-at-death estimation |
| WO2022261513A1 (en) * | 2021-06-10 | 2022-12-15 | Kang Zhang | Methods and systems of detecting and predicting chronic kidney disease and type 2 diabetes using deep learning models |
| CN113337617B (zh) * | 2021-06-29 | 2022-05-10 | 宁德师范学院 | 大黄鱼dna甲基化的分子标记及其在育种中的应用 |
| GB202110825D0 (en) * | 2021-07-28 | 2021-09-08 | Ucl Business Ltd | Methods for assessing epigenetic age and cancer risk |
| CN113584182A (zh) * | 2021-07-31 | 2021-11-02 | 广东海洋大学 | 一种与四川牦牛牛肉肉色红度性状相关的slc27a5基因的遗传标记 |
| US11781175B1 (en) | 2022-06-02 | 2023-10-10 | H42, Inc. | PCR-based epigenetic age prediction |
| WO2023084486A1 (en) * | 2021-11-12 | 2023-05-19 | H42, Inc. | Generation of epigenetic age information |
| WO2023090901A1 (ko) * | 2021-11-18 | 2023-05-25 | 의료법인 성광의료재단 | 기계 학습을 이용한 세포 노화의 마커를 선별하는 방법, 세포 노화 바이오 마커, 및 이를 이용한 세놀리틱 제제를 스크리닝 하는 방법 |
| WO2024015628A2 (en) * | 2022-07-15 | 2024-01-18 | The Board Of Trustees Of The Leland Stanford Junior University | Organ aging biomarkers derived from the plasma proteome |
| WO2024121349A1 (en) | 2022-12-08 | 2024-06-13 | Oncopeptides Ab | Therapeutic treatment for haematological cancer based on the level of t-cell function |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174681B1 (en) | 1999-03-05 | 2001-01-16 | Mayo Foundation For Medical Education And Research | Method and probe set for detecting cancer |
| DE10038733A1 (de) | 2000-08-02 | 2002-02-21 | Epigenomics Ag | Verfahren zur Altersbestimmung von Individuen |
| JP2012516148A (ja) * | 2009-01-30 | 2012-07-19 | ユニヴァーシティ オブ サウサンプトン | ＣｐＧメチル化の予測的使用 |
-
2013
- 2013-11-12 CA CA2929471A patent/CA2929471C/en active Active
- 2013-11-12 WO PCT/US2013/069710 patent/WO2014075083A1/en active Application Filing
- 2013-11-12 US US14/442,089 patent/US10087486B2/en active Active
- 2013-11-12 EP EP13852408.7A patent/EP2917371A4/en not_active Ceased
- 2013-11-12 CN CN201380070066.1A patent/CN105745333A/zh active Pending
-
2016
- 2016-09-22 HK HK16111169.4A patent/HK1223981A1/zh unknown
-
2018
- 2018-09-25 US US16/141,076 patent/US10718025B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US10718025B2 (en) | 2020-07-21 |
| EP2917371A1 (en) | 2015-09-16 |
| CA2929471C (en) | 2022-04-19 |
| US10087486B2 (en) | 2018-10-02 |
| EP2917371A4 (en) | 2016-10-12 |
| US20190032139A1 (en) | 2019-01-31 |
| CN105745333A (zh) | 2016-07-06 |
| CA2929471A1 (en) | 2014-05-15 |
| WO2014075083A1 (en) | 2014-05-15 |
| US20150259742A1 (en) | 2015-09-17 |
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