HK1220991A1 - 用於增加的重組蛋白產生的製劑和方法 - Google Patents

用於增加的重組蛋白產生的製劑和方法

Info

Publication number
HK1220991A1
HK1220991A1 HK16109114.4A HK16109114A HK1220991A1 HK 1220991 A1 HK1220991 A1 HK 1220991A1 HK 16109114 A HK16109114 A HK 16109114A HK 1220991 A1 HK1220991 A1 HK 1220991A1
Authority
HK
Hong Kong
Prior art keywords
formulations
methods
recombinant protein
protein production
increased recombinant
Prior art date
Application number
HK16109114.4A
Other languages
English (en)
Inventor
Yuval Shimoni
Volker Mhrle
Venkatesh Srinivasan
Ricaredo Matanguihan
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of HK1220991A1 publication Critical patent/HK1220991A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14Calcium; Ca chelators; Calcitonin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/30Organic components
    • C12N2500/34Sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
HK16109114.4A 2013-02-26 2016-08-01 用於增加的重組蛋白產生的製劑和方法 HK1220991A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361769402P 2013-02-26 2013-02-26
PCT/US2014/018428 WO2014134071A1 (en) 2013-02-26 2014-02-25 Formulations and methods for increased recombinant protein production

Publications (1)

Publication Number Publication Date
HK1220991A1 true HK1220991A1 (zh) 2017-05-19

Family

ID=50240092

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16109114.4A HK1220991A1 (zh) 2013-02-26 2016-08-01 用於增加的重組蛋白產生的製劑和方法

Country Status (18)

Country Link
US (2) US20160002592A1 (zh)
EP (1) EP2961827A1 (zh)
JP (1) JP2016508376A (zh)
KR (1) KR20150121701A (zh)
CN (1) CN105308174A (zh)
AR (1) AR094875A1 (zh)
AU (1) AU2014223680A1 (zh)
BR (1) BR112015020253A2 (zh)
CA (1) CA2902170A1 (zh)
EA (1) EA201591558A1 (zh)
HK (1) HK1220991A1 (zh)
IL (1) IL240639A0 (zh)
MX (1) MX2015010887A (zh)
PE (1) PE20152019A1 (zh)
SG (1) SG11201506212PA (zh)
TW (1) TW201522634A (zh)
UY (1) UY35343A (zh)
WO (1) WO2014134071A1 (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9481901B2 (en) 2013-05-30 2016-11-01 Amgen Inc. Methods for increasing mannose content of recombinant proteins
EP3409783B1 (de) * 2017-06-01 2020-12-16 Justus-Liebig-Universität Gießen Erfindung betreffend detektion und quantifizierung von colistin-resistenz bei gram-negativen bakterien
CN112006522B (zh) * 2019-05-31 2022-01-28 佛山市顺德区美的电热电器制造有限公司 烹饪器具、用于烹饪器具的烹饪附件以及控制方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6238891B1 (en) * 1987-11-18 2001-05-29 Cetus Oncology Corporation Method of increasing product expression through solute stress
CA2111561A1 (en) * 1992-05-01 1993-11-11 Yoshiharu Takazawa Fed batch culture method for protein secreting cells
CN101198621A (zh) * 2005-01-25 2008-06-11 阿波罗生命科学有限公司 分子及其嵌合分子
EP1844068A4 (en) * 2005-01-25 2009-09-30 Apollo Life Sciences Ltd MOLECULES AND THEIR CHIMERIC MOLECULES
DE102005046225B4 (de) * 2005-09-28 2012-01-05 Cellca Gmbh Verbessertes Zellkulturmedium
WO2008128228A1 (en) * 2007-04-16 2008-10-23 Momenta Pharmaceuticals, Inc. Methods related to cell surface glycosylation
GB0915481D0 (en) * 2009-09-04 2009-10-07 Arecor Ltd Stable manufacture of factor V111
US8969304B2 (en) * 2010-04-09 2015-03-03 The Institute For Cancer Research Compositions and methods for the prevention of cancer in high risk patients
PL3064508T5 (pl) * 2010-07-08 2024-04-08 Takeda Pharmaceutical Company Limited Sposób wytwarzania rekombinowanego vwf o dużej masie cząsteczkowej w hodowli komórkowej
CN102971006A (zh) * 2010-07-15 2013-03-13 诺沃—诺迪斯克有限公司 稳定的因子viii变体

Also Published As

Publication number Publication date
IL240639A0 (en) 2015-09-24
US20160002592A1 (en) 2016-01-07
BR112015020253A2 (pt) 2017-07-18
MX2015010887A (es) 2015-12-01
US20180010090A1 (en) 2018-01-11
UY35343A (es) 2014-09-30
WO2014134071A1 (en) 2014-09-04
CN105308174A (zh) 2016-02-03
PE20152019A1 (es) 2016-01-29
KR20150121701A (ko) 2015-10-29
CA2902170A1 (en) 2014-09-04
AR094875A1 (es) 2015-09-02
TW201522634A (zh) 2015-06-16
JP2016508376A (ja) 2016-03-22
EA201591558A1 (ru) 2016-03-31
SG11201506212PA (en) 2015-09-29
AU2014223680A1 (en) 2015-09-17
EP2961827A1 (en) 2016-01-06

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