HK1218751A1 - 羅丹明化合物及其作為熒光標記物的用途 - Google Patents

羅丹明化合物及其作為熒光標記物的用途

Info

Publication number
HK1218751A1
HK1218751A1 HK16106737.7A HK16106737A HK1218751A1 HK 1218751 A1 HK1218751 A1 HK 1218751A1 HK 16106737 A HK16106737 A HK 16106737A HK 1218751 A1 HK1218751 A1 HK 1218751A1
Authority
HK
Hong Kong
Prior art keywords
fluorescent labels
rhodamine compounds
rhodamine
compounds
labels
Prior art date
Application number
HK16106737.7A
Other languages
English (en)
Inventor
Nikolai Nikolaevich Romanov
Xiaohai Liu
Original Assignee
Illumina Cambridge Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Cambridge Ltd filed Critical Illumina Cambridge Ltd
Publication of HK1218751A1 publication Critical patent/HK1218751A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B11/00—Diaryl- or thriarylmethane dyes
    • C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
    • C09B11/10—Amino derivatives of triarylmethanes
    • C09B11/24—Phthaleins containing amino groups ; Phthalanes; Fluoranes; Phthalides; Rhodamine dyes; Phthaleins having heterocyclic aryl rings; Lactone or lactame forms of triarylmethane dyes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
HK16106737.7A 2013-03-08 2016-06-13 羅丹明化合物及其作為熒光標記物的用途 HK1218751A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2013/054793 WO2014135223A1 (en) 2013-03-08 2013-03-08 Rhodamine compounds and their use as fluorescent labels

Publications (1)

Publication Number Publication Date
HK1218751A1 true HK1218751A1 (zh) 2017-03-10

Family

ID=47882139

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16104498.1A HK1216642A1 (zh) 2013-03-08 2016-04-19 羅丹明化合物及其作為螢光標記物的用途
HK16106737.7A HK1218751A1 (zh) 2013-03-08 2016-06-13 羅丹明化合物及其作為熒光標記物的用途

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK16104498.1A HK1216642A1 (zh) 2013-03-08 2016-04-19 羅丹明化合物及其作為螢光標記物的用途

Country Status (8)

Country Link
EP (1) EP2964624B1 (zh)
CN (1) CN105263918B (zh)
AU (1) AU2013380647B2 (zh)
CA (1) CA2902992C (zh)
DK (1) DK2964624T3 (zh)
ES (1) ES2620427T3 (zh)
HK (2) HK1216642A1 (zh)
WO (1) WO2014135223A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201414098D0 (en) 2014-08-08 2014-09-24 Illumina Cambridge Ltd Modified nucleotide linkers
US10190162B2 (en) 2014-10-23 2019-01-29 Complete Genomics, Inc. Signal confinement sequencing (SCS) and nucleotide analogues for signal confinement sequencing
CN107459482B (zh) * 2016-06-03 2020-11-17 华东理工大学 一氧化氮供体、其制备及应用
US10385214B2 (en) 2016-09-30 2019-08-20 Illumina Cambridge Limited Fluorescent dyes and their uses as biomarkers
EP4257596A3 (en) * 2016-12-22 2023-12-06 Illumina Cambridge Limited Coumarin compounds and their uses as fluorescent labels
GB201711219D0 (en) * 2017-07-12 2017-08-23 Illumina Cambridge Ltd Short pendant arm linkers for nucleotides in sequencing applications
CN114671843B (zh) * 2020-12-24 2023-07-04 郑州思昆生物工程有限公司 一种荧光化合物、荧光修饰核苷酸、试剂盒
CN114671842B (zh) * 2020-12-24 2024-05-28 郑州思昆生物工程有限公司 一种荧光化合物及其制备方法、荧光修饰核苷酸、试剂盒

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB517097A (en) 1937-12-10 1940-01-19 Adrianus Kleijn An improved apparatus for testing the quality of grain and flour
US5268486A (en) 1986-04-18 1993-12-07 Carnegie-Mellon Unversity Method for labeling and detecting materials employing arylsulfonate cyanine dyes
US5302509A (en) 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
US5846719A (en) 1994-10-13 1998-12-08 Lynx Therapeutics, Inc. Oligonucleotide tags for sorting and identification
ES2563643T3 (es) 1997-04-01 2016-03-15 Illumina Cambridge Limited Método de secuenciación de ácido nucleico
US6465178B2 (en) 1997-09-30 2002-10-15 Surmodics, Inc. Target molecule attachment to surfaces
US6485944B1 (en) 1997-10-10 2002-11-26 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
GB0002310D0 (en) 2000-02-01 2000-03-22 Solexa Ltd Polynucleotide sequencing
EP1105529B2 (en) 1998-07-30 2013-05-29 Illumina Cambridge Limited Arrayed biomolecules and their use in sequencing
AR021833A1 (es) 1998-09-30 2002-08-07 Applied Research Systems Metodos de amplificacion y secuenciacion de acido nucleico
US6391937B1 (en) 1998-11-25 2002-05-21 Motorola, Inc. Polyacrylamide hydrogels and hydrogel arrays made from polyacrylamide reactive prepolymers
US6372813B1 (en) 1999-06-25 2002-04-16 Motorola Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays
US6664061B2 (en) 1999-06-25 2003-12-16 Amersham Biosciences Ab Use and evaluation of a [2+2] photoaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix
WO2002012566A2 (en) 2000-08-09 2002-02-14 Motorola, Inc. The use and evaluation of a [2+2] photocycloaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix
AU2001294859A1 (en) 2000-09-29 2002-04-08 Molecular Probes, Inc. Modified carbocyanine dyes and their conjugates
JP2006509040A (ja) 2002-08-23 2006-03-16 ソレックサ リミテッド 修飾されたヌクレオチド
HUE032483T2 (en) 2002-08-23 2017-09-28 Illumina Cambridge Ltd Marked nucleotides
DE10258150A1 (de) 2002-12-10 2004-07-08 Dyomics Gmbh Hydrophile Marker auf der Basis von Benzopyrylo-Polymethinen
GB0321306D0 (en) 2003-09-11 2003-10-15 Solexa Ltd Modified polymerases for improved incorporation of nucleotide analogues
GB0326073D0 (en) 2003-11-07 2003-12-10 Solexa Ltd Improvements in or relating to polynucleotide arrays
EP3673986A1 (en) 2004-01-07 2020-07-01 Illumina Cambridge Limited Improvements in or relating to molecular arrays
US8623628B2 (en) 2005-05-10 2014-01-07 Illumina, Inc. Polymerases
GB0517097D0 (en) 2005-08-19 2005-09-28 Solexa Ltd Modified nucleosides and nucleotides and uses thereof
EP2001871B1 (en) * 2006-03-31 2014-07-16 Applied Biosystems, LLC Rhodamine-labeled oligonucleotides
EP2021415B1 (en) 2006-05-18 2017-03-15 Illumina Cambridge Limited Dye compounds and the use of their labelled conjugates
US8951938B2 (en) * 2007-12-20 2015-02-10 New York University Combinatorial rosamine library to detect cell-state switching
EP2331520A4 (en) * 2008-09-19 2012-06-06 Cancer Res Initiative Foundation ROSAMINE DERIVATIVES AS AGENTS FOR CANCER TREATMENT

Also Published As

Publication number Publication date
CN105263918A (zh) 2016-01-20
AU2013380647B2 (en) 2017-05-04
CN105263918B (zh) 2018-05-18
WO2014135223A1 (en) 2014-09-12
CA2902992A1 (en) 2014-09-12
AU2013380647A1 (en) 2015-10-01
EP2964624B1 (en) 2017-01-04
HK1216642A1 (zh) 2016-11-25
EP2964624A1 (en) 2016-01-13
DK2964624T3 (en) 2017-04-03
ES2620427T3 (es) 2017-06-28
CA2902992C (en) 2020-08-25

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