HK1216300A1 - 作為 通道抑制劑的基於吡唑基的甲醯胺 - Google Patents

作為 通道抑制劑的基於吡唑基的甲醯胺

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Publication number
HK1216300A1
HK1216300A1 HK16104294.7A HK16104294A HK1216300A1 HK 1216300 A1 HK1216300 A1 HK 1216300A1 HK 16104294 A HK16104294 A HK 16104294A HK 1216300 A1 HK1216300 A1 HK 1216300A1
Authority
HK
Hong Kong
Prior art keywords
crac
pyrazolyl
channel inhibitors
carboxamides
based carboxamides
Prior art date
Application number
HK16104294.7A
Other languages
English (en)
Inventor
Sonja Nordhoff
Sebastian Wachten
Achim Kless
Felix Voss
Stefanie Ritter
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of HK1216300A1 publication Critical patent/HK1216300A1/zh

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07—ORGANIC CHEMISTRY
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    • C—CHEMISTRY; METALLURGY
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
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    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
HK16104294.7A 2013-01-10 2016-04-14 作為 通道抑制劑的基於吡唑基的甲醯胺 HK1216300A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13000118 2013-01-10
PCT/EP2014/000043 WO2014108337A1 (en) 2013-01-10 2014-01-10 Pyrazolyl-based carboxamides i as crac channel inhibitors

Publications (1)

Publication Number Publication Date
HK1216300A1 true HK1216300A1 (zh) 2016-11-04

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HK16104294.7A HK1216300A1 (zh) 2013-01-10 2016-04-14 作為 通道抑制劑的基於吡唑基的甲醯胺

Country Status (14)

Country Link
US (1) US9206136B2 (zh)
EP (1) EP2943196A1 (zh)
JP (1) JP2016508152A (zh)
KR (1) KR20150103751A (zh)
CN (1) CN104994851A (zh)
AR (1) AR094412A1 (zh)
AU (1) AU2014204978A1 (zh)
BR (1) BR112015016391A2 (zh)
CA (1) CA2897562A1 (zh)
EA (1) EA201500736A1 (zh)
HK (1) HK1216300A1 (zh)
IL (1) IL239790A0 (zh)
MX (1) MX2015008919A (zh)
WO (1) WO2014108337A1 (zh)

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WO2019081485A1 (de) 2017-10-26 2019-05-02 Bayer Cropscience Aktiengesellschaft Substituierte pyrazole sowie deren salze und ihre verwendung als herbizide wirkstoffe
AU2019340601A1 (en) 2018-09-14 2021-05-13 Rhizen Pharmaceuticals A G Compositions comprising a CRAC inhibitor and a corticosteroid and methods of use thereof
US20240010638A1 (en) * 2020-11-13 2024-01-11 Calcimedica, Inc. Improved synthesis of crac channel inhibitors

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AU2014204978A1 (en) 2015-08-20
BR112015016391A2 (pt) 2017-07-11
JP2016508152A (ja) 2016-03-17
EA201500736A1 (ru) 2016-04-29
CA2897562A1 (en) 2014-07-17
AR094412A1 (es) 2015-07-29
US9206136B2 (en) 2015-12-08
IL239790A0 (en) 2015-08-31
KR20150103751A (ko) 2015-09-11
US20140194443A1 (en) 2014-07-10
CN104994851A (zh) 2015-10-21
EP2943196A1 (en) 2015-11-18

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