HK1211360A1 - 與基於網絡的生物標記簽名相關的系統和方法 - Google Patents

與基於網絡的生物標記簽名相關的系統和方法

Info

Publication number
HK1211360A1
HK1211360A1 HK15112140.7A HK15112140A HK1211360A1 HK 1211360 A1 HK1211360 A1 HK 1211360A1 HK 15112140 A HK15112140 A HK 15112140A HK 1211360 A1 HK1211360 A1 HK 1211360A1
Authority
HK
Hong Kong
Prior art keywords
network
systems
methods relating
based biomarker
biomarker signatures
Prior art date
Application number
HK15112140.7A
Other languages
English (en)
Inventor
弗洛裡安‧馬丁
阿蘭‧塞韋爾
朱麗婭‧亨格
曼紐爾‧克勞德‧派奇
Original Assignee
Philip Morris Products Sa
Florian Martin
Alain Sewer
Julia Hoeng
Manuel Claude Peitsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products Sa, Florian Martin, Alain Sewer, Julia Hoeng, Manuel Claude Peitsch filed Critical Philip Morris Products Sa
Publication of HK1211360A1 publication Critical patent/HK1211360A1/zh

Links

Classifications

    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N20/00—Machine learning
    • G06N20/10—Machine learning using kernel methods, e.g. support vector machines [SVM]
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N5/00—Computing arrangements using knowledge-based models
    • G06N5/04—Inference or reasoning models
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
    • G16B5/30—Dynamic-time models

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Data Mining & Analysis (AREA)
  • Software Systems (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • Molecular Biology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Public Health (AREA)
  • Bioethics (AREA)
  • Physiology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Mathematical Physics (AREA)
  • General Engineering & Computer Science (AREA)
  • Computing Systems (AREA)
  • Computational Linguistics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HK15112140.7A 2012-06-21 2015-12-09 與基於網絡的生物標記簽名相關的系統和方法 HK1211360A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261662806P 2012-06-21 2012-06-21
US201261671954P 2012-07-16 2012-07-16
PCT/EP2013/062979 WO2013190083A1 (en) 2012-06-21 2013-06-21 Systems and methods relating to network-based biomarker signatures

Publications (1)

Publication Number Publication Date
HK1211360A1 true HK1211360A1 (zh) 2016-05-20

Family

ID=48670562

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15112140.7A HK1211360A1 (zh) 2012-06-21 2015-12-09 與基於網絡的生物標記簽名相關的系統和方法

Country Status (7)

Country Link
US (2) US20150220838A1 (zh)
EP (1) EP2864915B8 (zh)
JP (1) JP6320999B2 (zh)
CN (1) CN104704499B (zh)
CA (1) CA2877426C (zh)
HK (1) HK1211360A1 (zh)
WO (1) WO2013190083A1 (zh)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10339464B2 (en) 2012-06-21 2019-07-02 Philip Morris Products S.A. Systems and methods for generating biomarker signatures with integrated bias correction and class prediction
WO2013190085A1 (en) 2012-06-21 2013-12-27 Philip Morris Products S.A. Systems and methods for generating biomarker signatures with integrated dual ensemble and generalized simulated annealing techniques
KR102074026B1 (ko) * 2012-10-22 2020-02-05 아브 이니티오 테크놀로지 엘엘시 위치 정보를 가진 데이터 프로파일링
WO2015022336A1 (en) * 2013-08-12 2015-02-19 Philip Morris Products S.A. Systems and methods for crowd-verification of biological networks
CN105612524B (zh) 2013-09-13 2019-04-02 菲利普莫里斯生产公司 评估生物外源性物质代谢扰动的系统和方法
WO2015134193A1 (en) 2014-03-07 2015-09-11 Ab Initio Technology Llc Managing data profiling operations related to data type
KR101721528B1 (ko) * 2015-05-28 2017-03-31 아주대학교산학협력단 질병 네트워크로부터 동반 발병 확률을 제공하는 방법
CN106446599A (zh) * 2015-08-11 2017-02-22 中国科学院青岛生物能源与过程研究所 一种筛选婴幼儿龋病的口腔致病性生物标记物的方法
US10192642B2 (en) * 2016-05-10 2019-01-29 Macau University Of Science And Technology System and method for determining an association of at least one biological feature with a medical condition
US20170329914A1 (en) * 2016-05-11 2017-11-16 International Business Machines Corporation Predicting Personalized Cancer Metastasis Routes, Biological Mediators of Metastasis and Metastasis Blocking Therapies
CN107451596B (zh) * 2016-05-30 2020-04-14 清华大学 一种网络节点分类方法及装置
EP3465200A4 (en) * 2016-06-05 2020-07-08 Berg LLC PATIENT STRATIFICATION SYSTEMS AND METHODS AND IDENTIFICATION OF POTENTIAL BIOMARKERS
US10529253B2 (en) * 2016-08-30 2020-01-07 Bernard De Bono Method for organizing information and generating images of biological structures as well as related resources and the images and materials so generated
US20190318802A1 (en) * 2016-10-13 2019-10-17 University Of Florida Research Foundation, Incorporated Method and apparatus for improved determination of node influence in a network
US20180251849A1 (en) * 2017-03-03 2018-09-06 General Electric Company Method for identifying expression distinguishers in biological samples
US20200332364A1 (en) * 2017-05-12 2020-10-22 Laboratory Corporation Of America Holdings Compositions and methods for detection of diseases related to exposure to inhaled carcinogens
CN108228757A (zh) * 2017-12-21 2018-06-29 北京市商汤科技开发有限公司 图像搜索方法和装置、电子设备、存储介质、程序
US11024403B2 (en) * 2018-01-22 2021-06-01 X Development Llc Method for analyzing and optimizing metabolic networks
US11068540B2 (en) 2018-01-25 2021-07-20 Ab Initio Technology Llc Techniques for integrating validation results in data profiling and related systems and methods
EP3746472A2 (en) * 2018-01-31 2020-12-09 Regeneron Pharmaceuticals, Inc. Glucuronylation as acidic post-translational modification on therapeutic monoclonal antibodies
US10706328B2 (en) * 2018-05-07 2020-07-07 Google Llc Focus-weighted, machine learning disease classifier error prediction for microscope slide images
EP3575813B1 (en) * 2018-05-30 2022-06-29 Siemens Healthcare GmbH Quantitative mapping of a magnetic resonance imaging parameter by data-driven signal-model learning
EP3801623A4 (en) * 2018-06-01 2022-03-23 Grail, LLC NEURAL CONVOLUTIONAL NETWORK SYSTEMS AND DATA CLASSIFICATION METHODS
CN108614536B (zh) * 2018-06-11 2020-10-27 云南中烟工业有限责任公司 一种卷烟制丝工艺关键因素的复杂网络构建方法
EP3837566A1 (en) * 2018-08-14 2021-06-23 Cisco Technology, Inc. Motion detection for passive indoor positioning system
US11942189B2 (en) 2019-01-16 2024-03-26 International Business Machines Corporation Drug efficacy prediction for treatment of genetic disease
CN109756893B (zh) * 2019-01-25 2022-03-01 黑龙江大学 一种基于混沌映射的群智感知物联网匿名用户认证方法
US11915827B2 (en) * 2019-03-14 2024-02-27 Kenneth Neumann Methods and systems for classification to prognostic labels
US11393590B2 (en) * 2019-04-02 2022-07-19 Kpn Innovations, Llc Methods and systems for an artificial intelligence alimentary professional support network for vibrant constitutional guidance
US11710069B2 (en) * 2019-06-03 2023-07-25 Kpn Innovations, Llc. Methods and systems for causative chaining of prognostic label classifications
US10593431B1 (en) * 2019-06-03 2020-03-17 Kpn Innovations, Llc Methods and systems for causative chaining of prognostic label classifications
US10515715B1 (en) 2019-06-25 2019-12-24 Colgate-Palmolive Company Systems and methods for evaluating compositions
CN113128743B (zh) * 2020-01-15 2024-05-28 北京京东振世信息技术有限公司 一种拣货路径规划方法和装置
WO2023178152A1 (en) * 2022-03-15 2023-09-21 The University Of North Carolina At Chapel Hill Improved methods of predicting response to immune checkpoint blockade therapies and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7865534B2 (en) * 2002-09-30 2011-01-04 Genstruct, Inc. System, method and apparatus for assembling and mining life science data
US7240042B2 (en) * 2004-08-25 2007-07-03 Siemens Medical Solutions Usa, Inc. System and method for biological data analysis using a bayesian network combined with a support vector machine
JP5028847B2 (ja) * 2006-04-21 2012-09-19 富士通株式会社 遺伝子間相互作用ネットワーク分析支援プログラム、該プログラムを記録した記録媒体、遺伝子間相互作用ネットワーク分析支援方法、および、遺伝子間相互作用ネットワーク分析支援装置
CN101110095B (zh) * 2006-07-20 2010-06-30 中国科学院自动化研究所 一种对常见脑疾病易感基因的批量检测方法
WO2011119868A2 (en) * 2010-03-24 2011-09-29 Nodality, Inc. Hyper-spatial methods for modeling biological events

Also Published As

Publication number Publication date
CN104704499A (zh) 2015-06-10
CA2877426C (en) 2024-05-21
US20210397995A1 (en) 2021-12-23
CA2877426A1 (en) 2013-12-27
CN104704499B (zh) 2018-12-11
EP2864915B1 (en) 2022-05-04
WO2013190083A1 (en) 2013-12-27
JP6320999B2 (ja) 2018-05-09
US20150220838A1 (en) 2015-08-06
JP2015525412A (ja) 2015-09-03
EP2864915B8 (en) 2022-06-15
EP2864915A1 (en) 2015-04-29

Similar Documents

Publication Publication Date Title
HK1211360A1 (zh) 與基於網絡的生物標記簽名相關的系統和方法
GB2509400B (en) Rigid-stem lead-in-method and system
PL2833119T3 (pl) Układ do badania parametrów dynamicznych
GB2504570B (en) Microtome having an auto-rocking mode
GB2507498B (en) Secure computing environment
GB201508155D0 (en) Compact dehumidifiers and associated systems and methods
BR112014031384A2 (pt) métodos e sistemas
HK1210302A1 (zh) 用於增強型微小借貸的新系統和處理
HK1210643A1 (zh) 先進的數據庫系統和方法
EP2860366A4 (en) ENGINE SYSTEM
EP2828615A4 (en) LASER GRAMMING SYSTEM AND METHOD
IL238317B (en) Piping systems and methods
HK1212390A1 (zh) 試驗方法和系統
HK1209202A1 (zh) 用於生成生物標誌物簽名的系統和方法
GB201306147D0 (en) Novel biomarker signature and uses thereof
GB201318039D0 (en) Engine system
GB2503080B (en) An engine system
SG11201500259XA (en) Methods and systems for order matching
DE102013112830A8 (de) Turboladersystem
EP2883014A4 (en) THREAT SIMULATION SYSTEM
EP2877978A4 (en) SYSTEMS AND METHODS FOR NETWORK PROBLEM SOLVING
GB201203111D0 (en) Turbocharger
EP2989581A4 (en) Location signatures
GB2498400B (en) Turbocharger arrangement
ZA201305877B (en) Methods and systems for an engine

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230615