HK1208598A1 - 治療疼痛的方法及組合物 - Google Patents

治療疼痛的方法及組合物

Info

Publication number
HK1208598A1
HK1208598A1 HK15109316.1A HK15109316A HK1208598A1 HK 1208598 A1 HK1208598 A1 HK 1208598A1 HK 15109316 A HK15109316 A HK 15109316A HK 1208598 A1 HK1208598 A1 HK 1208598A1
Authority
HK
Hong Kong
Prior art keywords
compositions
methods
treating pain
pain
treating
Prior art date
Application number
HK15109316.1A
Other languages
English (en)
Inventor
陳志成
林雲蓮
方俊民
陳儀莊
林家靖
陳威男
林君榮
Original Assignee
Academia Sinica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Academia Sinica filed Critical Academia Sinica
Publication of HK1208598A1 publication Critical patent/HK1208598A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8988—Gastrodia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
HK15109316.1A 2012-02-11 2015-09-23 治療疼痛的方法及組合物 HK1208598A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261597742P 2012-02-11 2012-02-11
PCT/US2013/025580 WO2013120078A1 (en) 2012-02-11 2013-02-11 Methods and compositions for treating pain

Publications (1)

Publication Number Publication Date
HK1208598A1 true HK1208598A1 (zh) 2016-03-11

Family

ID=48948096

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109316.1A HK1208598A1 (zh) 2012-02-11 2015-09-23 治療疼痛的方法及組合物

Country Status (6)

Country Link
US (2) US20150038445A1 (zh)
EP (1) EP2849566B1 (zh)
CN (2) CN107252433A (zh)
HK (1) HK1208598A1 (zh)
TW (2) TW201603814A (zh)
WO (1) WO2013120078A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013120078A1 (en) 2012-02-11 2013-08-15 Academia Sinica Methods and compositions for treating pain
WO2015061426A1 (en) * 2013-10-23 2015-04-30 Academia Sinica Compounds for use in prevention and treatment of neurodegenerative diseases and pain
TWI668007B (zh) * 2014-11-11 2019-08-11 中央研究院 用於預防及治療神經退化疾病及疼痛之化合物
TWI650328B (zh) * 2014-11-11 2019-02-11 中央研究院 用於預防及治療神經退化疾病及疼痛之化合物
CN108329372B (zh) * 2017-01-20 2022-07-26 浙江省亚热带作物研究所 N6-(2-羟乙基)腺苷及其衍生物在制备治疗痛风药物中的应用
CN110799517A (zh) * 2017-01-27 2020-02-14 中央研究院 用于预防及治疗疼痛的具有止痛效果的化合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679650A (en) * 1993-11-24 1997-10-21 Fukunaga; Atsuo F. Pharmaceutical compositions including mixtures of an adenosine compound and a catecholamine
US6180616B1 (en) * 1990-05-10 2001-01-30 Atsuo F. Fukunaga Use of purine receptor agonists to alleviate or normalize physiopathologically excited sensory nerve function
US5677290A (en) * 1990-05-10 1997-10-14 Fukunaga; Atsuo F. Therapeutic use of adenosine compounds as surgical anesthetics
US6004945A (en) * 1990-05-10 1999-12-21 Fukunaga; Atsuo F. Use of adenosine compounds to relieve pain
SE9401499D0 (sv) * 1994-05-02 1994-05-02 Item Dev Ab New method of treatment
AU3255097A (en) * 1996-07-05 1998-02-02 Novo Nordisk A/S Novel (n)-alkoxyadenine derivatives acting as cytokine inhibitors
US6110902A (en) 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
GB9813554D0 (en) * 1998-06-23 1998-08-19 Glaxo Group Ltd Chemical compounds
US7825102B2 (en) * 2004-07-28 2010-11-02 Can-Fite Biopharma Ltd. Treatment of dry eye conditions
US7351434B2 (en) * 2006-04-07 2008-04-01 Academia Sinica Therapeutic Gastrodia extracts
US8129357B2 (en) * 2006-04-07 2012-03-06 Academia Sinica Method of making and using an adenosine analogue
WO2008000745A2 (en) * 2006-06-27 2008-01-03 Biovitrum Ab (Publ) Adenosine derivatives for the treatment of pain
BRPI0907248A2 (pt) 2008-01-09 2019-02-26 Pgxhealth, Llc tratamento intratecal de dor neuropática com agonistas a2ar
US20120295863A1 (en) * 2009-11-13 2012-11-22 Yun-Lian Lin Dual-Action Compounds Targeting Adenosine A2A Receptor and Adenosine Transporter for Prevention and Treatment of Neurodegenerative Diseases
CN102812033B (zh) * 2009-12-10 2015-11-25 中国医学科学院药物研究所 N6-取代腺苷衍生物和n6-取代腺嘌呤衍生物及其用途
US9132131B2 (en) * 2011-04-21 2015-09-15 Saint Louis University Use of adenosine A3 receptor agonists for treatment of neuropathic pain
WO2013120078A1 (en) 2012-02-11 2013-08-15 Academia Sinica Methods and compositions for treating pain

Also Published As

Publication number Publication date
EP2849566A1 (en) 2015-03-25
US20150038445A1 (en) 2015-02-05
EP2849566A4 (en) 2015-08-19
WO2013120078A1 (en) 2013-08-15
TW201336500A (zh) 2013-09-16
TW201603814A (zh) 2016-02-01
EP2849566B1 (en) 2018-04-04
CN107252433A (zh) 2017-10-17
US10117890B2 (en) 2018-11-06
US20170224716A1 (en) 2017-08-10
TWI494111B (zh) 2015-08-01
CN104363757A (zh) 2015-02-18
CN104363757B (zh) 2017-05-24

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