HK1203567A1 - Determining fetal dna percentage for twins dna - Google Patents

Determining fetal dna percentage for twins dna

Info

Publication number
HK1203567A1
HK1203567A1 HK15104100.2A HK15104100A HK1203567A1 HK 1203567 A1 HK1203567 A1 HK 1203567A1 HK 15104100 A HK15104100 A HK 15104100A HK 1203567 A1 HK1203567 A1 HK 1203567A1
Authority
HK
Hong Kong
Prior art keywords
dna
twins
percentage
determining fetal
fetal dna
Prior art date
Application number
HK15104100.2A
Other languages
English (en)
Chinese (zh)
Inventor
Yuk Ming Dennis Lo
Wai Kwun Rossa Chiu
Kwan Chee Chan
Tak Yeung Leung
Peiyong Jiang
Original Assignee
Univ Hong Kong Chinese
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Hong Kong Chinese filed Critical Univ Hong Kong Chinese
Publication of HK1203567A1 publication Critical patent/HK1203567A1/xx

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    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30Unsupervised data analysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/40Population genetics; Linkage disequilibrium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Evolutionary Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Data Mining & Analysis (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Software Systems (AREA)
  • Bioethics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Artificial Intelligence (AREA)
  • Databases & Information Systems (AREA)
  • Evolutionary Computation (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HK15104100.2A 2011-02-24 2014-06-20 Determining fetal dna percentage for twins dna HK1203567A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161446256P 2011-02-24 2011-02-24

Publications (1)

Publication Number Publication Date
HK1203567A1 true HK1203567A1 (en) 2015-10-30

Family

ID=47753591

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15104100.2A HK1203567A1 (en) 2011-02-24 2014-06-20 Determining fetal dna percentage for twins dna

Country Status (9)

Country Link
US (2) US10900080B2 (de)
EP (5) EP3489368B1 (de)
JP (2) JP5837622B2 (de)
CN (2) CN103492589B (de)
AU (1) AU2012311262C1 (de)
CA (2) CA3160848A1 (de)
HK (1) HK1203567A1 (de)
TW (1) TWI611186B (de)
WO (1) WO2013041921A1 (de)

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RS58879B1 (sr) 2009-11-05 2019-08-30 Univ Hong Kong Chinese Analiza genoma fetusa iz majčinskog biološkog uzorka
US11322224B2 (en) * 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
EP3489368B1 (de) 2011-02-24 2020-09-09 The Chinese University Of Hong Kong Molekulares testen mehrerer schwangerschaften
US10424394B2 (en) 2011-10-06 2019-09-24 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
WO2013173993A1 (zh) * 2012-05-23 2013-11-28 深圳华大基因健康科技有限公司 鉴定双胞胎类型的方法和系统
US10482994B2 (en) 2012-10-04 2019-11-19 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
TWI489305B (zh) * 2012-11-21 2015-06-21 Bgi Diagnosis Co Ltd 對胎兒遺傳異常的無創性檢測
KR102241051B1 (ko) 2013-02-28 2021-04-16 더 차이니즈 유니버시티 오브 홍콩 대량 동시 rna 서열분석에 의한 모체 혈장 전사물 분석
CN105121660B (zh) * 2013-03-15 2018-09-28 香港中文大学 确定多胎妊娠的胎儿基因组
EP3011051B1 (de) 2013-06-21 2019-01-30 Sequenom, Inc. Verfahren zur nichtinvasiven beurteilung genetischer variationen
AU2016295712B2 (en) * 2015-07-20 2022-06-02 The Chinese University Of Hong Kong Methylation pattern analysis of haplotypes in tissues in DNA mixture
EP3518974A4 (de) 2016-09-29 2020-05-27 Myriad Women's Health, Inc. Nichtinvasives pränatales screening unter verwendung von dynamischer iterativer tiefenoptimierung
US11441174B2 (en) 2017-06-02 2022-09-13 Affymetrix, Inc. Array-based methods for analysing mixed samples using differently labelled allele-specific probes
EP3631008A1 (de) 2017-06-02 2020-04-08 Affymetrix, Inc. Array-basiertes verfahren zur analyse von gemischten proben unter verwendung unterschiedlich markierter allelspezifischer sonden
WO2018223057A1 (en) * 2017-06-02 2018-12-06 Affymetrix, Inc. Array-based methods for analysing mixed samples using different allele-specific labels, in particular for detection of fetal aneuploidies
SG11201911530RA (en) 2017-06-20 2020-01-30 Illumina Inc Methods for accurate computational decomposition of dna mixtures from contributors of unknown genotypes
CN112634986A (zh) * 2019-09-24 2021-04-09 厦门希吉亚生物科技有限公司 一种基于孕妇外周血对双胞胎合子性质的无创鉴定方法
KR102162831B1 (ko) 2019-12-26 2020-10-08 주식회사 마크로젠 혼합 모델을 이용한 쌍태아의 접합성 타입 결정 방법 및 분석 장치
EP4266315A1 (de) * 2020-12-16 2023-10-25 Seedna Inc. Verfahren zur berechnung des zuverlässigkeitswerts eines signals von polymorphismusloci
CN114214425B (zh) * 2020-12-23 2024-01-19 上海亿康医学检验所有限公司 一种鉴定核酸样本的亲本倾向性的方法或装置
CN113981062B (zh) * 2021-10-14 2024-02-20 武汉蓝沙医学检验实验室有限公司 以非生父和母亲dna评估胎儿dna浓度的方法及应用
WO2023120783A1 (ko) * 2021-12-24 2023-06-29 주식회사 마크로젠 혼합 모델을 이용한 쌍태아의 접합성 타입 결정 방법 및 분석 장치

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GB9704444D0 (en) 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
US6013449A (en) 1997-11-26 2000-01-11 The United States Of America As Represented By The Department Of Health And Human Services Probe-based analysis of heterozygous mutations using two-color labelling
WO2002055985A2 (en) 2000-11-15 2002-07-18 Roche Diagnostics Corp Methods and reagents for identifying rare fetal cells in the material circulation
US6927028B2 (en) 2001-08-31 2005-08-09 Chinese University Of Hong Kong Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA
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Also Published As

Publication number Publication date
CN106011237B (zh) 2019-12-13
JP2016034282A (ja) 2016-03-17
WO2013041921A1 (en) 2013-03-28
CN103492589A (zh) 2014-01-01
EP2678451B1 (de) 2017-04-26
AU2012311262C1 (en) 2017-06-29
EP3489368B1 (de) 2020-09-09
US10900080B2 (en) 2021-01-26
US20130059733A1 (en) 2013-03-07
TW201243326A (en) 2012-11-01
EP3489368A1 (de) 2019-05-29
JP2014507158A (ja) 2014-03-27
US20210095340A1 (en) 2021-04-01
CA2827873C (en) 2022-08-16
CN106011237A (zh) 2016-10-12
EP2860265A1 (de) 2015-04-15
TWI611186B (zh) 2018-01-11
CA3160848A1 (en) 2013-03-28
EP2678451A4 (de) 2014-10-22
CA2827873A1 (en) 2013-03-28
CN103492589B (zh) 2016-06-15
EP3202921A1 (de) 2017-08-09
EP2682887A2 (de) 2014-01-08
EP2678451A1 (de) 2014-01-01
AU2012311262B2 (en) 2014-10-09
JP5837622B2 (ja) 2015-12-24
EP3202921B1 (de) 2019-02-13
EP2860265B1 (de) 2016-10-26
JP6068598B2 (ja) 2017-01-25
AU2012311262A1 (en) 2013-05-02

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