HK1200482A1 - 利用藥物分子伴侶改善生物製劑的生產和純化 - Google Patents
利用藥物分子伴侶改善生物製劑的生產和純化Info
- Publication number
- HK1200482A1 HK1200482A1 HK14113034.5A HK14113034A HK1200482A1 HK 1200482 A1 HK1200482 A1 HK 1200482A1 HK 14113034 A HK14113034 A HK 14113034A HK 1200482 A1 HK1200482 A1 HK 1200482A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- biologics
- purification
- utilization
- improve manufacturing
- pharmacological chaperones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2445—Beta-glucosidase (3.2.1.21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01021—Beta-glucosidase (3.2.1.21)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18125509P | 2009-05-26 | 2009-05-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1200482A1 true HK1200482A1 (zh) | 2015-08-07 |
Family
ID=43223053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK14113034.5A HK1200482A1 (zh) | 2009-05-26 | 2013-01-08 | 利用藥物分子伴侶改善生物製劑的生產和純化 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20110070643A1 (zh) |
| EP (1) | EP2435459B1 (zh) |
| JP (1) | JP5805630B2 (zh) |
| CN (2) | CN102574887A (zh) |
| AU (1) | AU2010254092B2 (zh) |
| CA (1) | CA2763464C (zh) |
| ES (1) | ES2585584T3 (zh) |
| HK (1) | HK1200482A1 (zh) |
| IL (1) | IL216543A (zh) |
| WO (1) | WO2010138608A1 (zh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2533050T6 (pl) | 2006-05-16 | 2016-05-31 | Amicus Therapeutics Inc | Możliwości leczenia choroby Fabry'ego |
| HUE051377T2 (hu) | 2008-02-12 | 2021-03-01 | Amicus Therapeutics Inc | Eljárás betegségek gyógyászati chaperonnal történõ kezelésére adott válasz elõrejelzésére |
| BR112018013151A2 (pt) | 2015-12-30 | 2018-12-18 | Amicus Therapeutics Inc | alfa-glicosidase ácida aumentada para o tratamento da doença de pompe |
| PT3957320T (pt) * | 2015-12-30 | 2023-11-23 | Amicus Therapeutics Inc | Alfa-glicosidase ácida aumentada para o tratamento da doença de pompe |
| JP2017195786A (ja) * | 2016-04-25 | 2017-11-02 | 国立大学法人 熊本大学 | 細胞内酵素タンパク質の構造異常の正常化方法、細胞内酵素タンパク質の構造異常の検出方法、及び、遺伝性代謝病の治療方法ならびにその治療効果の予測・評価方法 |
| WO2018222655A1 (en) | 2017-05-30 | 2018-12-06 | Amicus Therapeutics, Inc. | Methods of treating fabry patients having renal impairment |
| CN108828121B (zh) * | 2018-06-14 | 2020-06-05 | 华润三九医药股份有限公司 | 一种白树药材中α-高野尻霉素的含量检测方法 |
| US11833164B2 (en) | 2019-08-07 | 2023-12-05 | Amicus Therapeutics, Inc. | Methods of treating Fabry disease in patients having a mutation in the GLA gene |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6274597B1 (en) * | 1998-06-01 | 2001-08-14 | Mount Sinai School Of Medicine Of New York University | Method of enhancing lysosomal α-Galactosidase A |
| US7842470B2 (en) * | 2001-10-09 | 2010-11-30 | Oregon Health & Science University | Method for pharmacoperones correction of GnRHR mutant protein misfolding |
| AU2004208990B2 (en) * | 2003-01-29 | 2010-11-11 | Oregon Health & Science University | Restoring function to gonadotropin releasing hormone receptor mutants |
| PT2441467E (pt) * | 2003-01-31 | 2015-10-12 | Sinai School Medicine | Terapia combinada para o tratamento de transtornos associados a uma deficiência proteica |
| US7446098B2 (en) * | 2003-02-18 | 2008-11-04 | Mount Sinai School Of Medicine Of New York University | Combination therapy for treating protein deficiencies |
| WO2007150064A2 (en) * | 2006-06-23 | 2007-12-27 | Amicus Therapeutics, Inc. | METHOD FOR THE TREATMENT OF NEUROLOGICAL DISORDERS BY ENHANCING THE ACTIVITY OF β-GLUCOCEREBROSIDASE |
| WO2008054947A2 (en) * | 2006-10-02 | 2008-05-08 | The Brigham And Women's Hospital, Inc. | Structure of acid beta-glucosidase and methods for identifying therapeutic agents |
| AU2008240205A1 (en) * | 2007-04-13 | 2008-10-23 | Amicus Therapeutics, Inc. | Use of substrates as pharmacological chaperones |
-
2010
- 2010-05-26 CA CA2763464A patent/CA2763464C/en not_active Expired - Fee Related
- 2010-05-26 AU AU2010254092A patent/AU2010254092B2/en not_active Ceased
- 2010-05-26 CN CN2010800289187A patent/CN102574887A/zh active Pending
- 2010-05-26 EP EP10781143.2A patent/EP2435459B1/en active Active
- 2010-05-26 CN CN201410325462.0A patent/CN104164412A/zh active Pending
- 2010-05-26 WO PCT/US2010/036225 patent/WO2010138608A1/en active Application Filing
- 2010-05-26 JP JP2012513221A patent/JP5805630B2/ja active Active
- 2010-05-26 ES ES10781143.2T patent/ES2585584T3/es active Active
- 2010-05-26 US US12/788,068 patent/US20110070643A1/en not_active Abandoned
-
2011
- 2011-11-23 IL IL216543A patent/IL216543A/en active IP Right Grant
-
2013
- 2013-01-08 HK HK14113034.5A patent/HK1200482A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2763464A1 (en) | 2010-12-02 |
| JP2012527900A (ja) | 2012-11-12 |
| CN102574887A (zh) | 2012-07-11 |
| AU2010254092A1 (en) | 2011-12-15 |
| WO2010138608A1 (en) | 2010-12-02 |
| EP2435459B1 (en) | 2016-05-04 |
| IL216543A (en) | 2015-11-30 |
| EP2435459A4 (en) | 2014-01-15 |
| JP5805630B2 (ja) | 2015-11-04 |
| ES2585584T3 (es) | 2016-10-06 |
| IL216543A0 (en) | 2012-02-29 |
| US20110070643A1 (en) | 2011-03-24 |
| CN104164412A (zh) | 2014-11-26 |
| EP2435459A1 (en) | 2012-04-04 |
| CA2763464C (en) | 2018-11-06 |
| AU2010254092B2 (en) | 2015-11-12 |
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