HK1177452A1 - Fluoro-substituted 2-aryl-3,5-dicyano-4-indazolyl-6-methyl-1,4- dihydropyridines and uses thereof 2--3,5--4--6--1,4- - Google Patents
Fluoro-substituted 2-aryl-3,5-dicyano-4-indazolyl-6-methyl-1,4- dihydropyridines and uses thereof 2--3,5--4--6--1,4-Info
- Publication number
- HK1177452A1 HK1177452A1 HK13102938.6A HK13102938A HK1177452A1 HK 1177452 A1 HK1177452 A1 HK 1177452A1 HK 13102938 A HK13102938 A HK 13102938A HK 1177452 A1 HK1177452 A1 HK 1177452A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dihydropyridines
- dicyano
- indazolyl
- fluoro
- aryl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09175642 | 2009-11-11 | ||
PCT/EP2010/066983 WO2011069761A1 (en) | 2009-11-11 | 2010-11-08 | Fluoro-substituted 2-aryl-3,5-dicyano-4-indazolyl-6-methyl-1,4-dihydropyridines and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1177452A1 true HK1177452A1 (en) | 2013-08-23 |
Family
ID=43629143
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK13102938.6A HK1177452A1 (en) | 2009-11-11 | 2013-03-08 | Fluoro-substituted 2-aryl-3,5-dicyano-4-indazolyl-6-methyl-1,4- dihydropyridines and uses thereof 2--3,5--4--6--1,4- |
Country Status (8)
Country | Link |
---|---|
US (1) | US9018234B2 (ja) |
EP (1) | EP2499124B1 (ja) |
JP (1) | JP5753182B2 (ja) |
CN (1) | CN102666525B (ja) |
CA (1) | CA2777907C (ja) |
ES (1) | ES2549132T3 (ja) |
HK (1) | HK1177452A1 (ja) |
WO (1) | WO2011069761A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104513253A (zh) | 2013-10-01 | 2015-04-15 | 南京波尔泰药业科技有限公司 | 用于治疗增殖性疾病的大环化合物 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3635977A (en) | 1969-11-03 | 1972-01-18 | American Cyanamid Co | Certain 6-trifluoromethylcytosines and thiocytosines their synthesis and their use in the synthesis of uracisls and thiouracil |
EP1720855A4 (en) | 2004-03-02 | 2008-12-17 | Smithkline Beecham Corp | HEMMER OF ACT ACTIVITY |
CA2589777A1 (en) | 2004-12-13 | 2006-06-22 | Irm Llc | Compounds and compositions as modulators of steroidal receptors and calcium channel activities |
CA2603676A1 (en) | 2005-01-07 | 2006-07-13 | Roskamp Research Llc | Compounds for inhibiting beta-amyloid production and methods of identifying the compounds |
CL2007003609A1 (es) | 2006-12-14 | 2008-07-25 | Bayer Schering Pharma Ag | Compuestos derivados de dihidropiridinas sustituidas; proceso de preparacion; compuestos intermediarios; composicion farmaceutica; proceso para producir la composicion farmaceutica; y uso en el tratamiento de una enfermedad mejorada con la inhibicion |
-
2010
- 2010-11-08 WO PCT/EP2010/066983 patent/WO2011069761A1/en active Application Filing
- 2010-11-08 CN CN201080050319.5A patent/CN102666525B/zh not_active Expired - Fee Related
- 2010-11-08 CA CA2777907A patent/CA2777907C/en not_active Expired - Fee Related
- 2010-11-08 EP EP10775812.0A patent/EP2499124B1/en not_active Not-in-force
- 2010-11-08 US US13/509,047 patent/US9018234B2/en not_active Expired - Fee Related
- 2010-11-08 JP JP2012538292A patent/JP5753182B2/ja not_active Expired - Fee Related
- 2010-11-08 ES ES10775812.0T patent/ES2549132T3/es active Active
-
2013
- 2013-03-08 HK HK13102938.6A patent/HK1177452A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2777907A1 (en) | 2011-06-16 |
CA2777907C (en) | 2017-08-29 |
CN102666525B (zh) | 2015-01-28 |
US20130005773A1 (en) | 2013-01-03 |
ES2549132T3 (es) | 2015-10-23 |
EP2499124B1 (en) | 2015-08-19 |
JP5753182B2 (ja) | 2015-07-22 |
WO2011069761A1 (en) | 2011-06-16 |
US9018234B2 (en) | 2015-04-28 |
JP2013510814A (ja) | 2013-03-28 |
CN102666525A (zh) | 2012-09-12 |
EP2499124A1 (en) | 2012-09-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20191108 |