HK1166645A1 - Enzymatic synthesis of carba-nad carba-nad - Google Patents
Enzymatic synthesis of carba-nad carba-nadInfo
- Publication number
- HK1166645A1 HK1166645A1 HK12107334.6A HK12107334A HK1166645A1 HK 1166645 A1 HK1166645 A1 HK 1166645A1 HK 12107334 A HK12107334 A HK 12107334A HK 1166645 A1 HK1166645 A1 HK 1166645A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- carba
- nad
- enzymatic synthesis
- enzymatic
- synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09166457 | 2009-07-27 | ||
| PCT/EP2010/004523 WO2011012270A1 (en) | 2009-07-27 | 2010-07-23 | Enzymatic synthesis of carba-nad |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1166645A1 true HK1166645A1 (en) | 2012-11-02 |
Family
ID=41412946
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12107334.6A HK1166645A1 (en) | 2009-07-27 | 2012-07-25 | Enzymatic synthesis of carba-nad carba-nad |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8580949B2 (xx) |
| EP (1) | EP2459728B1 (xx) |
| JP (1) | JP5540096B2 (xx) |
| CN (1) | CN102471793B (xx) |
| CA (1) | CA2769155C (xx) |
| ES (1) | ES2425631T3 (xx) |
| HK (1) | HK1166645A1 (xx) |
| WO (1) | WO2011012270A1 (xx) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2425631T3 (es) * | 2009-07-27 | 2013-10-16 | F. Hoffmann-La Roche Ag | Síntesis enzimática de carba-NAD |
| CN103347858B (zh) * | 2011-01-26 | 2016-09-14 | 霍夫曼-拉罗奇有限公司 | 制备n-取代的吡啶鎓化合物的方法和物质 |
| CN102605026B (zh) * | 2012-03-06 | 2013-04-17 | 苏州汉酶生物技术有限公司 | 一种氧化型辅酶i的制备方法 |
| CN102605027B (zh) * | 2012-03-06 | 2013-04-17 | 苏州汉酶生物技术有限公司 | 一种氧化型辅酶ii的酶催化制备方法 |
| CN103233051B (zh) * | 2012-12-19 | 2016-01-27 | 浙江嘉华化工有限公司 | 一种化学生物合成法规模化制备尼克酰胺腺嘌呤二核苷酸的方法 |
| KR101750638B1 (ko) | 2012-12-20 | 2017-06-23 | 에프. 호프만-라 로슈 아게 | 체액의 샘플을 분석하는 방법 |
| KR101789893B1 (ko) | 2012-12-20 | 2017-11-20 | 에프. 호프만-라 로슈 아게 | 의학적 측정 곡선들을 평가하기 위한 방법 |
| EP2781919A1 (en) | 2013-03-19 | 2014-09-24 | Roche Diagniostics GmbH | Method / device for generating a corrected value of an analyte concentration in a sample of a body fluid |
| CN105247069A (zh) | 2013-06-04 | 2016-01-13 | 豪夫迈·罗氏有限公司 | 用于fret的新化合物及与其相关的方法 |
| CN106884028B (zh) * | 2015-12-16 | 2020-10-16 | 中国科学院大连化学物理研究所 | 酶促合成烟酰胺尿嘧啶二核苷酸的方法 |
| CN106884029B (zh) * | 2015-12-16 | 2020-10-30 | 中国科学院大连化学物理研究所 | 酶促合成烟酰胺胞嘧啶二核苷酸的方法 |
| CN108350439A (zh) | 2015-12-21 | 2018-07-31 | 豪夫迈·罗氏有限公司 | 来自粪产碱菌的突变体3-羟基丁酸脱氢酶及其相关方法和用途 |
| WO2017137491A1 (en) | 2016-02-09 | 2017-08-17 | Roche Diabetes Care Gmbh | Mutant 3-hydroxybutyrate dehydrogenase from rhodobacter sphaeroides as well as methods and uses involving the same |
| CN109804240A (zh) | 2016-10-05 | 2019-05-24 | 豪夫迈·罗氏有限公司 | 用于多分析物诊断测试元件的检测试剂和电极布置以及其使用方法 |
| EP3339431A1 (en) | 2016-12-22 | 2018-06-27 | Roche Diabetes Care GmbH | Glucose dehydrogenase variants with improved properties |
| EP3759231B1 (en) | 2018-02-28 | 2023-10-18 | F. Hoffmann-La Roche AG | Biocompatibility coating for continuous analyte measurement |
| CN112437813B (zh) * | 2019-06-27 | 2023-03-03 | 邦泰生物工程(深圳)有限公司 | 酶法工业化生产nad的方法 |
| CN112437811B (zh) * | 2019-06-27 | 2023-05-05 | 邦泰生物工程(深圳)有限公司 | 一种重组nad合成酶及其基因和应用 |
| CN111424064A (zh) * | 2020-04-20 | 2020-07-17 | 比瑞博生物科技(北京)有限公司 | 一种基于酶法的高纯度nmn制备工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102005035461A1 (de) * | 2005-07-28 | 2007-02-15 | Roche Diagnostics Gmbh | Stabile NAD/NADH-Derivate |
| JP2010215488A (ja) * | 2009-02-17 | 2010-09-30 | Sumitomo Chemical Co Ltd | チタン酸アルミニウム系セラミックス |
| EP2398909B1 (de) * | 2009-02-19 | 2015-07-22 | F. Hoffmann-La Roche AG | Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten |
| ES2425631T3 (es) * | 2009-07-27 | 2013-10-16 | F. Hoffmann-La Roche Ag | Síntesis enzimática de carba-NAD |
| EP2292751A1 (de) * | 2009-08-20 | 2011-03-09 | Roche Diagnostics GmbH | Stabilisierung von Enzymen mit stabilen Coenzymen |
| EP2287605A1 (de) * | 2009-08-20 | 2011-02-23 | Roche Diagnostics GmbH | Vereinfachte Magazinierung integrierter Systeme |
-
2010
- 2010-07-23 ES ES10742423T patent/ES2425631T3/es active Active
- 2010-07-23 WO PCT/EP2010/004523 patent/WO2011012270A1/en active Application Filing
- 2010-07-23 CA CA2769155A patent/CA2769155C/en active Active
- 2010-07-23 CN CN201080033434.1A patent/CN102471793B/zh active Active
- 2010-07-23 JP JP2012522013A patent/JP5540096B2/ja active Active
- 2010-07-23 EP EP10742423.6A patent/EP2459728B1/en active Active
-
2012
- 2012-01-25 US US13/358,146 patent/US8580949B2/en active Active
- 2012-07-25 HK HK12107334.6A patent/HK1166645A1/xx unknown
-
2013
- 2013-10-03 US US14/045,565 patent/US20140142291A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US8580949B2 (en) | 2013-11-12 |
| US20120130062A1 (en) | 2012-05-24 |
| CA2769155A1 (en) | 2011-02-03 |
| CN102471793A (zh) | 2012-05-23 |
| ES2425631T3 (es) | 2013-10-16 |
| CN102471793B (zh) | 2014-04-30 |
| JP5540096B2 (ja) | 2014-07-02 |
| EP2459728B1 (en) | 2013-06-05 |
| EP2459728A1 (en) | 2012-06-06 |
| JP2013500026A (ja) | 2013-01-07 |
| WO2011012270A1 (en) | 2011-02-03 |
| US20140142291A1 (en) | 2014-05-22 |
| WO2011012270A8 (en) | 2012-02-23 |
| CA2769155C (en) | 2015-04-28 |
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