HK1164886A1 - 合成吡美莫司的化學酶法 - Google Patents
合成吡美莫司的化學酶法Info
- Publication number
- HK1164886A1 HK1164886A1 HK12105808.7A HK12105808A HK1164886A1 HK 1164886 A1 HK1164886 A1 HK 1164886A1 HK 12105808 A HK12105808 A HK 12105808A HK 1164886 A1 HK1164886 A1 HK 1164886A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pimecrolimus
- chemo
- synthesis
- enzymatic approach
- enzymatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2009A000908A IT1394309B1 (it) | 2009-05-22 | 2009-05-22 | Nuovo approccio chimico-enzimatico alla sintesi del pimecrolimus |
| PCT/IB2010/052218 WO2010134027A1 (en) | 2009-05-22 | 2010-05-19 | A chemo-enzymatic approach to the synthesis of pimecrolimus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1164886A1 true HK1164886A1 (zh) | 2012-09-28 |
Family
ID=41259629
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12105808.7A HK1164886A1 (zh) | 2009-05-22 | 2012-06-14 | 合成吡美莫司的化學酶法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8778636B2 (zh) |
| EP (2) | EP2706061B1 (zh) |
| JP (1) | JP5787880B2 (zh) |
| CN (1) | CN102439023B (zh) |
| AU (1) | AU2010250802B2 (zh) |
| CA (1) | CA2763034C (zh) |
| ES (2) | ES2548847T3 (zh) |
| HK (1) | HK1164886A1 (zh) |
| IL (1) | IL216444A (zh) |
| IT (1) | IT1394309B1 (zh) |
| WO (1) | WO2010134027A1 (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3459975A1 (en) | 2011-02-28 | 2019-03-27 | Cadena Bio, Inc. | Polymeric acid catalysts and uses thereof |
| US9238845B2 (en) | 2012-08-24 | 2016-01-19 | Midori Usa, Inc. | Methods of producing sugars from biomass feedstocks |
| CN103023906B (zh) * | 2012-12-20 | 2017-04-19 | 北京奇虎科技有限公司 | 针对远程过程调用协议进行状态跟踪的方法及系统 |
| EP3178824A1 (en) | 2015-12-08 | 2017-06-14 | Medichem, S.A. | Process for preparing pimecrolimus |
| CA3060330A1 (en) | 2017-05-01 | 2018-11-08 | Meda Pharma Gmbh & Co. Kg | Process to convert crude ascomycin into purified pimecrolimus |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69021833T2 (de) * | 1989-11-09 | 1996-03-21 | Sandoz Ag | Heteroatome enthaltende tricyclische Verbindungen. |
| SG152234A1 (en) * | 2004-04-14 | 2009-05-29 | Wyeth Corp | Regiospecific synthesis of rapamycin 42-ester derivatives |
| ITMI20041703A1 (it) | 2004-09-03 | 2004-12-03 | Poli Ind Chimica Spa | Metodo di preparazione del mofetil micofenolato per transesterificazione enzimatica |
| GT200500282A (es) | 2004-10-12 | 2006-05-04 | Heteroatomos conteniendo compuestos triciclicos. | |
| JP2007519758A (ja) | 2004-12-01 | 2007-07-19 | テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ | 結晶マクロライドの生成方法 |
| BRPI0708562A2 (pt) * | 2006-03-07 | 2011-06-07 | Wyeth Corp | processos para preparar conjugados de polietileno glicor de macrolìdeos imunossupressores, um macrolìdeo imunossupressor peguilado, uma rapamicina peguilada, um everolimus peguilado, um cci-779 peguilado e um tacrolimus peguilado, e, produto |
-
2009
- 2009-05-22 IT ITMI2009A000908A patent/IT1394309B1/it active
-
2010
- 2010-05-19 EP EP13193832.6A patent/EP2706061B1/en not_active Not-in-force
- 2010-05-19 CN CN201080022350.8A patent/CN102439023B/zh not_active Expired - Fee Related
- 2010-05-19 ES ES13193832.6T patent/ES2548847T3/es active Active
- 2010-05-19 ES ES10727887.1T patent/ES2548992T3/es active Active
- 2010-05-19 CA CA2763034A patent/CA2763034C/en not_active Expired - Fee Related
- 2010-05-19 WO PCT/IB2010/052218 patent/WO2010134027A1/en active Application Filing
- 2010-05-19 EP EP10727887.1A patent/EP2432791B1/en not_active Not-in-force
- 2010-05-19 AU AU2010250802A patent/AU2010250802B2/en not_active Ceased
- 2010-05-19 US US13/261,036 patent/US8778636B2/en not_active Expired - Fee Related
- 2010-05-19 JP JP2012511394A patent/JP5787880B2/ja not_active Expired - Fee Related
-
2011
- 2011-11-17 IL IL216444A patent/IL216444A/en not_active IP Right Cessation
-
2012
- 2012-06-14 HK HK12105808.7A patent/HK1164886A1/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL216444A0 (en) | 2012-02-29 |
| JP5787880B2 (ja) | 2015-09-30 |
| EP2706061A1 (en) | 2014-03-12 |
| AU2010250802A1 (en) | 2011-12-15 |
| EP2706061B1 (en) | 2015-07-08 |
| CA2763034A1 (en) | 2010-11-25 |
| JP2012527229A (ja) | 2012-11-08 |
| WO2010134027A1 (en) | 2010-11-25 |
| CA2763034C (en) | 2017-08-29 |
| IL216444A (en) | 2015-11-30 |
| US20120064575A1 (en) | 2012-03-15 |
| US8778636B2 (en) | 2014-07-15 |
| EP2432791A1 (en) | 2012-03-28 |
| CN102439023B (zh) | 2015-01-07 |
| ES2548992T3 (es) | 2015-10-22 |
| ES2548847T3 (es) | 2015-10-21 |
| ITMI20090908A1 (it) | 2010-11-23 |
| IT1394309B1 (it) | 2012-06-06 |
| EP2432791B1 (en) | 2015-07-08 |
| AU2010250802B2 (en) | 2014-05-22 |
| CN102439023A (zh) | 2012-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190518 |