HK1164869A1 - Azabicyclo compound and salt thereof - Google Patents
Azabicyclo compound and salt thereofInfo
- Publication number
- HK1164869A1 HK1164869A1 HK12105624.9A HK12105624A HK1164869A1 HK 1164869 A1 HK1164869 A1 HK 1164869A1 HK 12105624 A HK12105624 A HK 12105624A HK 1164869 A1 HK1164869 A1 HK 1164869A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- salt
- azabicyclo compound
- azabicyclo
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009164196 | 2009-07-10 | ||
| PCT/JP2010/004466 WO2011004610A1 (en) | 2009-07-10 | 2010-07-09 | Azabicyclo compound and salt thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1164869A1 true HK1164869A1 (en) | 2012-09-28 |
Family
ID=43429037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK12105624.9A HK1164869A1 (en) | 2009-07-10 | 2012-06-08 | Azabicyclo compound and salt thereof |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8779142B2 (en) |
| EP (1) | EP2452940B1 (en) |
| JP (1) | JP5227456B2 (en) |
| KR (1) | KR101609412B1 (en) |
| CN (2) | CN104710420B (en) |
| AU (1) | AU2010269674B2 (en) |
| BR (1) | BRPI1013999B1 (en) |
| CA (1) | CA2767556C (en) |
| DK (1) | DK2452940T3 (en) |
| ES (1) | ES2527222T3 (en) |
| HK (1) | HK1164869A1 (en) |
| MX (1) | MX2012000487A (en) |
| MY (1) | MY152972A (en) |
| PL (1) | PL2452940T3 (en) |
| PT (1) | PT2452940E (en) |
| RU (1) | RU2565078C2 (en) |
| SG (1) | SG177306A1 (en) |
| TW (1) | TWI460177B (en) |
| WO (1) | WO2011004610A1 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012009510A1 (en) * | 2010-07-15 | 2012-01-19 | Bristol-Myers Squibb Company | Azaindazole compounds |
| JP2013542259A (en) * | 2010-11-12 | 2013-11-21 | ブリストル−マイヤーズ スクイブ カンパニー | Substituted azaindazole compounds |
| ES2589557T3 (en) * | 2011-01-07 | 2016-11-15 | Taiho Pharmaceutical Co., Ltd. | New indole or indazole derivatives and salts thereof |
| WO2012093708A1 (en) * | 2011-01-07 | 2012-07-12 | 大鵬薬品工業株式会社 | Novel bicyclic compound or salt thereof |
| EP2760870B1 (en) | 2011-09-27 | 2016-05-04 | Bristol-Myers Squibb Company | Substituted bicyclic heteroaryl compounds |
| JP6242885B2 (en) | 2012-06-27 | 2017-12-06 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 5-azaindazole compounds and methods of use |
| PT3037424T (en) * | 2013-08-22 | 2017-12-18 | Taiho Pharmaceutical Co Ltd | Novel quinoline-substituted compound |
| US9694001B2 (en) | 2013-09-30 | 2017-07-04 | Taiho Pharmaceutical Co., Ltd. | Combination therapy using azabicyclo compound for cancer |
| WO2015050235A1 (en) | 2013-10-02 | 2015-04-09 | 大鵬薬品工業株式会社 | RESISTANT MUTANT 90 kDA HEAT SHOCK PROTEIN |
| KR102412146B1 (en) * | 2015-02-11 | 2022-06-22 | 주식회사 아이엔테라퓨틱스 | Sodium channel blockers |
| CN107531707B (en) | 2015-05-12 | 2020-01-10 | 大鹏药品工业株式会社 | Crystal of aza-bicyclic compound |
| JOP20190073A1 (en) | 2016-10-31 | 2019-04-07 | Taiho Pharmaceutical Co Ltd | Selective inhibitor of exon 20 insertion mutant egfr |
| CN108976150B (en) * | 2017-06-05 | 2022-11-18 | 重庆博腾制药科技股份有限公司 | Preparation method of 3-ethyl-4-fluorobenzonitrile |
| CA3068580A1 (en) | 2017-06-30 | 2019-01-03 | Taiho Pharmaceutical Co., Ltd. | Chemotherapy for cancer using azabicyclo compound |
| ES2972895T3 (en) | 2017-09-01 | 2024-06-17 | Taiho Pharmaceutical Co Ltd | Selective inhibitor of EGFR mutant in exon 18 and/or exon 21 |
| SG11202002316PA (en) * | 2017-09-15 | 2020-04-29 | Taiho Pharmaceutical Co Ltd | Prophylactic and/or therapeutic agent for diseases involving ido expression |
| WO2019220512A1 (en) | 2018-05-14 | 2019-11-21 | 大鵬薬品工業株式会社 | Method for treating malignant tumor with aza bicyclic compound |
| CN116615422A (en) * | 2020-10-14 | 2023-08-18 | 珃诺生物医药科技(杭州)有限公司 | Methods and compositions for targeting protein degradation |
| CN114685492A (en) * | 2020-12-31 | 2022-07-01 | 杭州领业医药科技有限公司 | TAS-116 crystal form, preparation method, pharmaceutical composition and application thereof |
| WO2022166796A1 (en) * | 2021-02-05 | 2022-08-11 | 上海齐鲁制药研究中心有限公司 | Pyrimidine or pyridine and heterocyclic adenosine receptor inhibitor, preparation method therefor and use thereof |
| CN117003754A (en) * | 2022-04-28 | 2023-11-07 | 腾讯科技（深圳）有限公司 | Pyrrolo [2,3-d ] pyrimidine or pyrazolo [3,4-d ] pyrimidine derivatives and uses thereof |
| CN115960100B (en) * | 2022-12-28 | 2023-08-18 | 北京康立生医药技术开发有限公司 | Synthesis method of Pi Mite xib drug for treating gastrointestinal stromal tumor |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5451566A (en) * | 1993-11-17 | 1995-09-19 | Zeneca Limited | Herbicidal pyrrolopyridine compounds |
| WO2005028434A2 (en) | 2003-09-18 | 2005-03-31 | Conforma Therapeutics Corporation | Novel heterocyclic compounds as hsp90-inhibitors |
| CA2557004A1 (en) * | 2003-12-19 | 2005-06-30 | Glaxo Group Limited | Pyrazolo [3,4-b] pyridine compounds, and their use as phosphodiesterase inhibitors |
| GB0425035D0 (en) | 2004-11-12 | 2004-12-15 | Novartis Ag | Organic compounds |
| RU2387653C2 (en) * | 2005-05-16 | 2010-04-27 | Айрм Ллк | Compounds and compositions as protein kinase inhibitors |
| EP1934185A1 (en) * | 2005-08-12 | 2008-06-25 | Synta Pharmaceuticals Corporation | Pyrazole compounds that modulate hsp90 activity |
| WO2007035620A2 (en) | 2005-09-16 | 2007-03-29 | Serenex, Inc. | Carbazole derivatives |
| US20080119457A1 (en) | 2006-08-24 | 2008-05-22 | Serenex, Inc. | Benzene, Pyridine, and Pyridazine Derivatives |
| GB0617161D0 (en) * | 2006-08-31 | 2006-10-11 | Vernalis R&D Ltd | Enzyme inhibitors |
| JP5401329B2 (en) * | 2007-03-20 | 2014-01-29 | キュリス，インコーポレイテッド | Condensed aminopyridines as HSP90 inhibitors |
| ES2395114T3 (en) * | 2007-03-27 | 2013-02-08 | Synta Pharmaceuticals Corporation | Triazinone and diazinone derivatives useful as Hsp90 inhibitors |
| RU2011142151A (en) * | 2009-03-19 | 2013-04-27 | Санофи | HSP90 INDAZOL INHIBITORS DERIVATIVES CONTAINING THEIR COMPOSITIONS AND USE |
| ES2589557T3 (en) | 2011-01-07 | 2016-11-15 | Taiho Pharmaceutical Co., Ltd. | New indole or indazole derivatives and salts thereof |
| WO2012093708A1 (en) | 2011-01-07 | 2012-07-12 | 大鵬薬品工業株式会社 | Novel bicyclic compound or salt thereof |
-
2010
- 2010-07-09 MX MX2012000487A patent/MX2012000487A/en active IP Right Grant
- 2010-07-09 CN CN201510129170.4A patent/CN104710420B/en active Active
- 2010-07-09 RU RU2012104700/04A patent/RU2565078C2/en active
- 2010-07-09 KR KR1020127000485A patent/KR101609412B1/en active IP Right Grant
- 2010-07-09 TW TW099122759A patent/TWI460177B/en active
- 2010-07-09 PL PL10796921T patent/PL2452940T3/en unknown
- 2010-07-09 US US13/378,527 patent/US8779142B2/en active Active
- 2010-07-09 AU AU2010269674A patent/AU2010269674B2/en active Active
- 2010-07-09 ES ES10796921.4T patent/ES2527222T3/en active Active
- 2010-07-09 CN CN201080031144.3A patent/CN102471335B/en active Active
- 2010-07-09 EP EP10796921.4A patent/EP2452940B1/en active Active
- 2010-07-09 SG SG2011094851A patent/SG177306A1/en unknown
- 2010-07-09 DK DK10796921.4T patent/DK2452940T3/en active
- 2010-07-09 WO PCT/JP2010/004466 patent/WO2011004610A1/en active Application Filing
- 2010-07-09 CA CA2767556A patent/CA2767556C/en active Active
- 2010-07-09 JP JP2011521828A patent/JP5227456B2/en active Active
- 2010-07-09 MY MYPI2011005616 patent/MY152972A/en unknown
- 2010-07-09 BR BRPI1013999-0A patent/BRPI1013999B1/en active IP Right Grant
- 2010-07-09 PT PT107969214T patent/PT2452940E/en unknown
-
2012
- 2012-06-08 HK HK12105624.9A patent/HK1164869A1/en unknown
-
2014
- 2014-04-01 US US14/242,063 patent/US9273045B2/en active Active
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