HK1158192A1 - Piperidine gpcr agonists - Google Patents
Piperidine gpcr agonistsInfo
- Publication number
- HK1158192A1 HK1158192A1 HK11112523.8A HK11112523A HK1158192A1 HK 1158192 A1 HK1158192 A1 HK 1158192A1 HK 11112523 A HK11112523 A HK 11112523A HK 1158192 A1 HK1158192 A1 HK 1158192A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- gpcr agonists
- piperidine
- piperidine gpcr
- agonists
- obesity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0812640A GB0812640D0 (en) | 2008-07-10 | 2008-07-10 | Compounds |
GB0902796A GB0902796D0 (en) | 2009-02-20 | 2009-02-20 | Compounds |
PCT/GB2009/050826 WO2010004344A1 (fr) | 2008-07-10 | 2009-07-10 | Agonistes des récepteurs couplés aux protéines g (gpcr) piperidines |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1158192A1 true HK1158192A1 (en) | 2012-07-13 |
Family
ID=41077623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11112523.8A HK1158192A1 (en) | 2008-07-10 | 2011-11-18 | Piperidine gpcr agonists |
Country Status (8)
Country | Link |
---|---|
US (1) | US20110230507A1 (fr) |
EP (1) | EP2321308B9 (fr) |
JP (1) | JP2011527332A (fr) |
CN (1) | CN102089301A (fr) |
AT (1) | ATE557024T1 (fr) |
ES (1) | ES2387865T3 (fr) |
HK (1) | HK1158192A1 (fr) |
WO (1) | WO2010004344A1 (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0904284D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
GB0904287D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
GB0904285D0 (en) | 2009-03-12 | 2009-04-22 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
WO2010149685A1 (fr) | 2009-06-24 | 2010-12-29 | Boehringer Ingelheim International Gmbh | Nouveaux composés, composition pharmaceutique et procédés s'y rapportant |
AU2010264720A1 (en) | 2009-06-24 | 2011-12-08 | Boehringer Ingelheim International Gmbh | New compounds, pharmaceutical composition and methods relating thereto |
US20130109703A1 (en) | 2010-03-18 | 2013-05-02 | Boehringer Ingelheim International Gmbh | Combination of a GPR119 Agonist and the DPP-IV Inhibitor Linagliptin for Use in the Treatment of Diabetes and Related Conditions |
GB201006166D0 (en) | 2010-04-14 | 2010-05-26 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
GB201006167D0 (en) | 2010-04-14 | 2010-05-26 | Prosidion Ltd | Compounds for the treatment of metabolic disorders |
MX2012013465A (es) | 2010-05-17 | 2013-12-02 | Array Biopharma Inc | Lactamas sustituidas con piperidinilo como moduladores de gpr119. |
TW201209054A (en) | 2010-05-28 | 2012-03-01 | Prosidion Ltd | Novel compounds |
US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
JP2013537234A (ja) * | 2010-09-17 | 2013-09-30 | アレイ バイオファーマ、インコーポレイテッド | Gpr119モジュレーターとしてのピペリジニル置換ラクタム |
GB201114389D0 (en) | 2011-08-22 | 2011-10-05 | Prosidion Ltd | Novel compounds |
AR083904A1 (es) | 2010-11-18 | 2013-04-10 | Prosidion Ltd | Derivados de 1,4-pirrolidinas disustituidos y 3-il-aminas y sus usos en el tratamiento de desordenes metabolicos |
CA2831334A1 (fr) | 2011-04-08 | 2012-10-11 | Merck Sharp & Dohme Corp. | Composes a cyclopropyle substitue, compositions contenant de tels composes et methodes de traitement |
US9006228B2 (en) | 2011-06-16 | 2015-04-14 | Merck Sharp & Dohme Corp. | Substituted cyclopropyl compounds, compositions containing such compounds, and methods of treatment |
WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
EP2760862B1 (fr) | 2011-09-27 | 2015-10-21 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
WO2013048916A1 (fr) | 2011-09-30 | 2013-04-04 | Merck Sharp & Dohme Corp. | Composés de cyclopropyle substitués, compositions contenant ces composés et méthodes de traitement |
WO2013062838A1 (fr) | 2011-10-24 | 2013-05-02 | Merck Sharp & Dohme Corp. | Composés de pipéridinyle substitués utilisés comme agonistes du récepteur gpr119 |
AU2012339870B2 (en) | 2011-11-15 | 2017-06-29 | Merck Sharp & Dohme Corp. | Substituted cyclopropyl compounds useful as GPR119 agonists |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6100042A (en) * | 1993-03-31 | 2000-08-08 | Cadus Pharmaceutical Corporation | Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor |
ZA977103B (en) * | 1996-08-09 | 1999-02-08 | Eisai Co Ltd | Benzopiperidine derivatives |
US6221660B1 (en) * | 1999-02-22 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding SNORF25 receptor |
DOP2006000008A (es) * | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
NZ564759A (en) * | 2005-06-30 | 2011-08-26 | Prosidion Ltd | GPCR agonists |
GB0700122D0 (en) * | 2007-01-04 | 2007-02-14 | Prosidion Ltd | GPCR agonists |
EA016507B1 (ru) * | 2007-01-04 | 2012-05-30 | Прозидион Лимитед | Пиперидиновые агонисты gpcr |
GB0812648D0 (en) * | 2008-07-10 | 2008-08-20 | Prosidion Ltd | Compounds |
-
2009
- 2009-07-10 EP EP09785304A patent/EP2321308B9/fr not_active Not-in-force
- 2009-07-10 CN CN2009801269900A patent/CN102089301A/zh active Pending
- 2009-07-10 WO PCT/GB2009/050826 patent/WO2010004344A1/fr active Application Filing
- 2009-07-10 US US13/003,567 patent/US20110230507A1/en not_active Abandoned
- 2009-07-10 JP JP2011517246A patent/JP2011527332A/ja not_active Withdrawn
- 2009-07-10 AT AT09785304T patent/ATE557024T1/de active
- 2009-07-10 ES ES09785304T patent/ES2387865T3/es active Active
-
2011
- 2011-11-18 HK HK11112523.8A patent/HK1158192A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2011527332A (ja) | 2011-10-27 |
EP2321308A1 (fr) | 2011-05-18 |
US20110230507A1 (en) | 2011-09-22 |
ATE557024T1 (de) | 2012-05-15 |
CN102089301A (zh) | 2011-06-08 |
ES2387865T3 (es) | 2012-10-03 |
WO2010004344A1 (fr) | 2010-01-14 |
EP2321308B9 (fr) | 2012-08-08 |
EP2321308B1 (fr) | 2012-05-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20160710 |