HK1145676A1 - Method for the preparation of ivabradine sulfate and form i thereof - Google Patents

Method for the preparation of ivabradine sulfate and form i thereof

Info

Publication number
HK1145676A1
HK1145676A1 HK10111668.6A HK10111668A HK1145676A1 HK 1145676 A1 HK1145676 A1 HK 1145676A1 HK 10111668 A HK10111668 A HK 10111668A HK 1145676 A1 HK1145676 A1 HK 1145676A1
Authority
HK
Hong Kong
Prior art keywords
preparation
ivabradine sulfate
ivabradine
sulfate
Prior art date
Application number
HK10111668.6A
Other languages
English (en)
Inventor
Piaoyang Sun
Yongjiang Chen
Guangliang Yu
Original Assignee
Jiangsu Hengrui Medicine Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Hengrui Medicine Co filed Critical Jiangsu Hengrui Medicine Co
Publication of HK1145676A1 publication Critical patent/HK1145676A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK10111668.6A 2009-01-13 2010-12-15 Method for the preparation of ivabradine sulfate and form i thereof HK1145676A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN200910003042XA CN101774969B (zh) 2009-01-13 2009-01-13 硫酸伊伐布雷定及其i型结晶的制备方法

Publications (1)

Publication Number Publication Date
HK1145676A1 true HK1145676A1 (en) 2011-04-29

Family

ID=42339422

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10111668.6A HK1145676A1 (en) 2009-01-13 2010-12-15 Method for the preparation of ivabradine sulfate and form i thereof

Country Status (6)

Country Link
US (1) US8541405B2 (xx)
EP (1) EP2388248B1 (xx)
JP (1) JP5640017B2 (xx)
CN (1) CN101774969B (xx)
HK (1) HK1145676A1 (xx)
WO (1) WO2010081342A1 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2528026T3 (es) 2007-05-30 2015-02-03 Ind-Swift Laboratories Limited Sales de oxalato de ivabridina cristalino y polimorfos de los mismos
US9440924B2 (en) 2011-08-02 2016-09-13 Sandoz Ag Acetone solvate of ivabradine hydrochloride
CZ2013767A3 (cs) 2013-10-02 2015-04-29 Zentiva, K.S. Pevná forma Ivabradin hydrochloridu a (S)-mandlové kyseliny a její farmaceutická kompozice
CZ305436B6 (cs) 2014-07-10 2015-09-16 Zentiva, K.S. Pevná forma Ivabradin hydrochloridu a (R)-mandlové kyseliny a její farmaceutická kompozice
GB201621771D0 (en) * 2016-12-20 2017-02-01 Biogena (A P I) Ltd New salts of compounds and uses thereof
IT202000025312A1 (it) 2020-10-26 2022-04-26 Cambrex Profarmaco Milano S R L Processi per la preparazione di polimorfi di ivabradina hcl

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3519735A1 (de) * 1985-06-01 1986-12-04 Dr. Karl Thomae Gmbh, 7950 Biberach Neue heteroaromatische aminderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
EP0204349A3 (de) * 1985-06-01 1990-01-03 Dr. Karl Thomae GmbH Neue heteroaromatische Aminderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
FR2681862B1 (fr) 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
JP2005066615A (ja) 2003-08-21 2005-03-17 Daihen Corp 消耗電極ガスシールドアーク溶接の溶接開始時アーク長制御方法
FR2882554B1 (fr) 2005-02-28 2007-05-04 Servier Lab Forme critalline beta d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882555B1 (fr) 2005-02-28 2007-05-04 Servier Lab Forme cristalline gamma du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882553B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882556B1 (fr) 2005-02-28 2007-05-04 Servier Lab Forme cristalline gamma d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2891826B1 (fr) 2005-10-11 2007-12-28 Servier Lab Forme cristalline 6 du chlorhydrate de l'ivabradine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2891827B1 (fr) 2005-10-11 2007-12-28 Servier Lab Forme cristalline deltad du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
ES2528026T3 (es) * 2007-05-30 2015-02-03 Ind-Swift Laboratories Limited Sales de oxalato de ivabridina cristalino y polimorfos de los mismos
FR2932800B1 (fr) * 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
FR2933975B1 (fr) * 2008-07-17 2011-02-18 Servier Lab Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable.
FR2935381B1 (fr) * 2008-08-29 2010-12-17 Servier Lab Nouveau procede de resolution des enantiomerees du (3,4-dimethoxy-bicyclo°4.2.0!octa-1,3,5-trien-7-yl)nitrile et application a la synthese de l'ivabradine

Also Published As

Publication number Publication date
CN101774969A (zh) 2010-07-14
EP2388248A4 (en) 2012-06-13
EP2388248A1 (en) 2011-11-23
US8541405B2 (en) 2013-09-24
JP5640017B2 (ja) 2014-12-10
JP2012515141A (ja) 2012-07-05
EP2388248B1 (en) 2015-07-29
CN101774969B (zh) 2012-07-04
WO2010081342A1 (zh) 2010-07-22
US20110275614A1 (en) 2011-11-10

Similar Documents

Publication Publication Date Title
EP2430112A4 (en) MATERIALS AND METHOD FOR PRODUCING NANOVERIC MATERIALS
EP2506967A4 (en) NANOPARTICLE COMPOSITION AND METHODS OF PREPARATION
TWI366890B (en) Method of manufacturing through-silicon-via and through-silicon-via structure
IL219486A0 (en) Fibrous structures and methods for making same
EP2646610A4 (en) LIQUID-THICK FILM AND MANUFACTURING METHOD THEREFOR
PL2459867T3 (pl) Dysza i sposób jej wytwarzania
EP2520288A4 (en) METHOD FOR PRODUCING A SOLID PREPARATION AND PREPARATION THEREOF PRODUCED BY THIS PROCESS
HK1164832A1 (en) Piceatannol-containing composition and method of producing piceatannol- containing composition
EP2373834A4 (en) COMPOSITE MATERIAL AND METHOD FOR PREPARING THE SAME
TWI371765B (en) Transformer structure and manufacturing method thereof
EP2519100A4 (en) INTERMEDIATE COMPOUNDS AND METHODS FOR THE PREPARATION OF TAPENTADOL AND RELATED COMPOUNDS
EP2513263A4 (en) DIESEL COMPOSITION AND PROCESS FOR PREPARING THE SAME
EP2535324A4 (en) 5-NORBORN-2-SPIRO-A-CYCLOALKANONEA 'SPIRO-2' '- 5' '- NORBORNES AND METHOD FOR THE PRODUCTION THEREOF
HRP20190015T1 (hr) Paneli od žbuke i postupci njihove proizvodnje
EP2459029A4 (en) MONOBLOCK STRUCTURES FOR SEAT AND METHOD OF FORMING THE SAME
EP2411465A4 (en) PROCESS FOR PREPARING A HETEROPHASIC COPOLYMER AND USES THEREOF
EP2465983A4 (en) METHOD FOR FORMING FABRIC AND FABRIC
HK1148560A1 (en) Mould for galvanoplasty and method of fabricating the same
HK1145676A1 (en) Method for the preparation of ivabradine sulfate and form i thereof
EP2394979A4 (en) INTERMEDIATE OF CILASTATIN AND METHOD FOR PREPARING THE SAME
EP2395972A4 (en) PARTICULATE COMPOSITION AND METHOD FOR PRODUCING THE SAME
EP2521141A4 (en) CORROSION-RESISTANT MAGNET AND METHOD FOR MANUFACTURING THE SAME
ZA201204133B (en) Health-beneficial preparation and production method
EP2366424A4 (en) AIR-PERMEABLE STRUCTURE AND METHOD OF FORMING AIR-PERMEABLE STRUCTURE
EP2649217A4 (en) ARTICLE AND METHOD FOR ITS MANUFACTURE AND USE

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230107