HK1139982A1 - Modified proteases - Google Patents

Modified proteases

Info

Publication number
HK1139982A1
HK1139982A1 HK10105356.5A HK10105356A HK1139982A1 HK 1139982 A1 HK1139982 A1 HK 1139982A1 HK 10105356 A HK10105356 A HK 10105356A HK 1139982 A1 HK1139982 A1 HK 1139982A1
Authority
HK
Hong Kong
Prior art keywords
modified proteases
proteases
modified
Prior art date
Application number
HK10105356.5A
Other languages
Chinese (zh)
Inventor
David A Estell
Eugenio Ferrari
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39743046&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1139982(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of HK1139982A1 publication Critical patent/HK1139982A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C07K14/18—Togaviridae; Flaviviridae
    • C07K14/19—Rubella virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
HK10105356.5A 2007-03-12 2010-06-01 Modified proteases HK1139982A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90673407P 2007-03-12 2007-03-12
PCT/US2008/003291 WO2008112258A2 (en) 2007-03-12 2008-03-12 Modified proteases

Publications (1)

Publication Number Publication Date
HK1139982A1 true HK1139982A1 (en) 2010-09-30

Family

ID=39743046

Family Applications (1)

Application Number Title Priority Date Filing Date
HK10105356.5A HK1139982A1 (en) 2007-03-12 2010-06-01 Modified proteases

Country Status (10)

Country Link
US (2) US8779112B2 (en)
EP (1) EP2129779B2 (en)
JP (1) JP5867984B2 (en)
KR (1) KR20090129425A (en)
CN (2) CN103667323B (en)
AU (1) AU2008226792B2 (en)
CA (1) CA2680563A1 (en)
HK (1) HK1139982A1 (en)
RU (1) RU2496875C2 (en)
WO (1) WO2008112258A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008226792B2 (en) * 2007-03-12 2013-06-06 Danisco Us Inc. Modified proteases
WO2010056634A1 (en) * 2008-11-11 2010-05-20 Danisco Us Inc. Compositions and methods comprising a subtilisin variant
DK2421973T3 (en) * 2009-04-24 2018-07-30 Danisco Us Inc PROTEAS WITH MODIFIED PRO AREAS
AR076311A1 (en) * 2009-07-31 2011-06-01 Danisco Us Inc PROTEASES WITH MODIFIED PRE-PRO REGIONS
GB0915572D0 (en) * 2009-09-07 2009-10-07 Reckitt Benckiser Nv Detergent composition
US20110281327A1 (en) * 2010-04-15 2011-11-17 Danisco Us Inc. Compositions And Methods Comprising Variant Proteases
US20170298302A1 (en) * 2014-10-30 2017-10-19 Novozymes A/S Protease Variants and Polynucleotides Encoding Same
WO2016205710A1 (en) * 2015-06-17 2016-12-22 Danisco Us Inc. Proteases with modified propeptide regions
CN109055288B (en) * 2018-06-30 2020-06-23 浙江工业大学 Recombinant bacillus subtilis and application thereof
KR102316445B1 (en) * 2019-11-29 2021-10-26 씨제이제일제당 주식회사 A novel serine protease variant
AU2021285906A1 (en) * 2020-06-03 2023-02-02 Molecular Assemblies, Inc. Modified template-independent enzymes for polydeoxynucleotide synthesis
WO2023192953A1 (en) 2022-04-01 2023-10-05 Danisco Us Inc. Pro-region mutations enhancing protein production in gram-positive bacterial cells
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
CN114836408B (en) * 2022-05-28 2023-09-19 湖北大学 Alkaline protease containing propeptide mutant and application thereof

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4302544A (en) 1979-10-15 1981-11-24 University Of Rochester Asporogenous mutant of B. subtilis for use as host component of HV1 system
US4450235A (en) 1982-04-21 1984-05-22 Cpc International Inc. Asporogenic mutant of bacillus subtilis useful as a host in a host-vector system
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US5310675A (en) 1983-06-24 1994-05-10 Genencor, Inc. Procaryotic carbonyl hydrolases
EP0134048B2 (en) 1983-07-06 1996-08-14 Gist-Brocades N.V. Molecular cloning and expression in industrial microorganism species
US5264366A (en) 1984-05-29 1993-11-23 Genencor, Inc. Protease deficient bacillus
US5763257A (en) 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
EP0254735B2 (en) 1986-01-15 1998-06-17 Amgen Inc. METHOD FOR PRODUCTION OF THERMALLY STABLE AND pH STABLE SUBTILISIN ANALOGS
US4980288A (en) 1986-02-12 1990-12-25 Genex Corporation Subtilisin with increased thermal stability
BR8805647A (en) 1987-02-27 1989-10-31 Gist Brocades Nv PROCESS FOR MOLECULAR CLONING AND EXPRESSION OF GENES THAT CODE FOR PROTEOLYTIC ENZYMES
US4914031A (en) 1987-04-10 1990-04-03 Amgen, Inc. Subtilisin analogs
DK6488D0 (en) 1988-01-07 1988-01-07 Novo Industri As ENZYMES
CN1056187C (en) 1988-02-11 2000-09-06 金克克国际有限公司 Proteolytic enzymes and their use in detergents
US5665587A (en) 1989-06-26 1997-09-09 Novo Nordisk A/S Modified subtilisins and detergent compositions containing same
DK97190D0 (en) 1990-04-19 1990-04-19 Novo Nordisk As OXIDATION STABLE DETERGENT ENZYMER
US5482849A (en) 1990-12-21 1996-01-09 Novo Nordisk A/S Subtilisin mutants
WO1992019729A1 (en) 1991-05-01 1992-11-12 Novo Nordisk A/S Stabilized enzymes and detergent compositions
DE4411223A1 (en) 1994-03-31 1995-10-05 Solvay Enzymes Gmbh & Co Kg Use of alkaline proteases in commercial textile washing processes
WO1998055634A1 (en) 1997-06-04 1998-12-10 The Procter & Gamble Company Protease enzymes for tough cleaning and/or spot and film reduction and compositions incorporating same
MA25044A1 (en) 1997-10-23 2000-10-01 Procter & Gamble WASHING COMPOSITIONS CONTAINING MULTISUBSTITUTED PROTEASE VARIANTS.
RU2269572C2 (en) * 1997-10-23 2006-02-10 Джененкор Интернэшнл, Инк. Multisubstituted protease (variants)
CA2313950A1 (en) 1997-12-24 1999-07-08 James T. Kellis, Jr. An improved method of assaying for a preferred enzyme and /or preferred detergent composition
US6835550B1 (en) 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
US7109016B2 (en) * 2000-08-21 2006-09-19 Novozymes A/S Subtilase enzymes
AU2001279614B2 (en) * 2000-08-21 2006-08-17 Novozymes A/S Subtilase enzymes
DE10162728A1 (en) * 2001-12-20 2003-07-10 Henkel Kgaa New alkaline protease from Bacillus gibsonii (DSM 14393) and washing and cleaning agents containing this new alkaline protease
DE10163883A1 (en) * 2001-12-22 2003-07-10 Henkel Kgaa New alkaline protease from Bacillus sp. (DSM 14390) and detergents and cleaning agents containing this new alkaline protease
EP1530631B1 (en) * 2002-01-16 2013-08-07 Genencor International, Inc. Multiply-substituted protease variants
EP2339016B8 (en) * 2002-03-29 2016-01-27 Danisco US Inc. Enhanced production of subtilisins in Bacillus
JP4210548B2 (en) * 2002-06-26 2009-01-21 花王株式会社 Alkaline protease
JP5639324B2 (en) * 2003-08-06 2014-12-10 ユニバーシティー オブ メリーランド，カレッジ パーク Modified protease for affinity purification and processing of fusion proteins
KR20090031906A (en) * 2006-07-18 2009-03-30 다니스코 유에스 인크. Protease variants active over a broad temperature range
AU2008226792B2 (en) * 2007-03-12 2013-06-06 Danisco Us Inc. Modified proteases
DK2421973T3 (en) * 2009-04-24 2018-07-30 Danisco Us Inc PROTEAS WITH MODIFIED PRO AREAS

Also Published As

Publication number Publication date
AU2008226792B2 (en) 2013-06-06
RU2496875C2 (en) 2013-10-27
US20090075332A1 (en) 2009-03-19
CN103667323B (en) 2016-02-03
CN101641438A (en) 2010-02-03
US8779112B2 (en) 2014-07-15
EP2129779B2 (en) 2018-12-26
WO2008112258A3 (en) 2008-11-20
CA2680563A1 (en) 2008-09-18
EP2129779B1 (en) 2016-03-09
CN103667323A (en) 2014-03-26
CN101641438B (en) 2013-12-25
AU2008226792A1 (en) 2008-09-18
RU2009137600A (en) 2011-04-20
US9523088B2 (en) 2016-12-20
JP2010521152A (en) 2010-06-24
US20140295526A1 (en) 2014-10-02
JP5867984B2 (en) 2016-02-24
WO2008112258A2 (en) 2008-09-18
EP2129779A2 (en) 2009-12-09
KR20090129425A (en) 2009-12-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20180312