HK1128293A1 - 古菌醣脂合成佐劑 - Google Patents

古菌醣脂合成佐劑

Info

Publication number
HK1128293A1
HK1128293A1 HK09104105.5A HK09104105A HK1128293A1 HK 1128293 A1 HK1128293 A1 HK 1128293A1 HK 09104105 A HK09104105 A HK 09104105A HK 1128293 A1 HK1128293 A1 HK 1128293A1
Authority
HK
Hong Kong
Prior art keywords
glycolipid adjuvants
synthetic archaeal
archaeal
synthetic
glycolipid
Prior art date
Application number
HK09104105.5A
Other languages
English (en)
Inventor
Dennis Sprott
Dennis Whitfield
Lakshmi Krishnan
Original Assignee
Nat Res Council Canada
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Council Canada filed Critical Nat Res Council Canada
Publication of HK1128293A1 publication Critical patent/HK1128293A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/06Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical being a hydroxyalkyl group esterified by a fatty acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55583Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588Adjuvants of undefined constitution
    • A61K2039/55594Adjuvants of undefined constitution from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
HK09104105.5A 2006-03-30 2009-05-05 古菌醣脂合成佐劑 HK1128293A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78717006P 2006-03-30 2006-03-30
US79122506P 2006-04-12 2006-04-12
PCT/CA2007/000530 WO2007112567A1 (en) 2006-03-30 2007-03-30 Synthetic archaeal glycolipid adjuvants

Publications (1)

Publication Number Publication Date
HK1128293A1 true HK1128293A1 (zh) 2009-10-23

Family

ID=38563043

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09104105.5A HK1128293A1 (zh) 2006-03-30 2009-05-05 古菌醣脂合成佐劑

Country Status (5)

Country Link
US (1) US8936793B2 (zh)
EP (1) EP1999137B1 (zh)
CA (1) CA2647060C (zh)
HK (1) HK1128293A1 (zh)
WO (1) WO2007112567A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1897557A1 (en) * 2006-09-07 2008-03-12 Helmholtz-Zentrum für Infektionsforschung GmbH Use of glycolipids as adjuvants
ITMI20130949A1 (it) * 2013-06-10 2014-12-11 Consiglio Nazionale Ricerche Uso e preparazione di glicolipidi come adiuvanti in vaccini
CA2946679A1 (en) * 2014-05-08 2015-11-12 Immunexcite, Inc. Immunomodulating .beta.-1,6-d-glucans
CA2954740C (en) 2014-07-11 2022-10-18 National Research Council Of Canada Sulfated-glycolipids as adjuvants for vaccines
FR3052361B1 (fr) 2016-06-09 2019-08-23 Centre National De La Recherche Scientifique Diethers d’archaea lipides synthetiques
EP3525817A4 (en) 2016-10-11 2020-09-16 The Governors of the University of Alberta IMMUNOGENIC HEPATITIS C VIRUS COMPOSITIONS WITH A CYCLIC DINUCLEOTIDE OR ARCHAEOSOME AS ADJUVANS AND METHOD OF USE THEREOF
EP3708151A1 (en) 2019-03-15 2020-09-16 Technische Universität Wien Method for producing a composition comprising archaeal lipids from a sulfolobus cell culture
EP4342460A1 (en) 2022-09-21 2024-03-27 NovoArc GmbH Lipid nanoparticle with nucleic acid cargo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6132789A (en) * 1995-12-15 2000-10-17 National Research Council Of Canada Archaeosomes, archaeosomes containing coenzyme Q10, and other types of liposomes containing coenzyme Q10 as adjuvants and as delivery vehicles
ES2320971T3 (es) * 1999-10-12 2009-06-01 National Research Council Of Canada Arqueosomas como adjuvantes y vehiculos para vacunas acelulares para inducir respuestas de linfocitos t cototoxicos.

Also Published As

Publication number Publication date
CA2647060C (en) 2014-10-21
US20100316657A1 (en) 2010-12-16
EP1999137A4 (en) 2013-04-10
US8936793B2 (en) 2015-01-20
EP1999137B1 (en) 2016-03-30
CA2647060A1 (en) 2007-10-11
WO2007112567A1 (en) 2007-10-11
EP1999137A1 (en) 2008-12-10

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