HK1122025A1 - - Google Patents

Info

Publication number
HK1122025A1
HK1122025A1 HK09102334.2A HK09102334A HK1122025A1 HK 1122025 A1 HK1122025 A1 HK 1122025A1 HK 09102334 A HK09102334 A HK 09102334A HK 1122025 A1 HK1122025 A1 HK 1122025A1
Authority
HK
Hong Kong
Prior art keywords
optionally substituted
alkoxy
disesae
atopic
hydrate
Prior art date
Application number
HK09102334.2A
Inventor
Kazuki Miyazaki
Kazutomi Kusano
Yasutaka Takase
Osamu Asano
Manabu Shirato
Hisashi Wakita
Naoto Ishii
Takao Saeki
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP2007/053066 external-priority patent/WO2007097317A1/en
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of HK1122025A1 publication Critical patent/HK1122025A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A compound represented by the following formula, salt thereof or hydrate thereof, can effectively relieve itch caused by atopic disesae or the like: wherein R represents hydroxyl, C1-6 alkoxy optionally substituted with C1-6 alkoxy, or amino optionally substituted with C1-6 alkyl.
HK09102334.2A 2006-02-21 2009-03-11 HK1122025A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006043273 2006-02-21
PCT/JP2007/053066 WO2007097317A1 (en) 2006-02-21 2007-02-20 4-(3-benzoylaminophenyl)-6,7-dimethoxy-2- methylaminoquinazoline derivative

Publications (1)

Publication Number Publication Date
HK1122025A1 true HK1122025A1 (en) 2009-05-08

Family

ID=42137992

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09102334.2A HK1122025A1 (en) 2006-02-21 2009-03-11

Country Status (18)

Country Link
JP (1) JP4778550B2 (en)
KR (1) KR101278852B1 (en)
AT (1) ATE517875T1 (en)
BR (1) BRPI0708098B8 (en)
CY (1) CY1112554T1 (en)
DK (1) DK1992622T3 (en)
ES (1) ES2368089T3 (en)
HK (1) HK1122025A1 (en)
HR (1) HRP20110604T1 (en)
IL (1) IL193322A (en)
JO (1) JO2726B1 (en)
MY (1) MY146275A (en)
NZ (1) NZ569936A (en)
PT (1) PT1992622E (en)
RS (1) RS51969B (en)
RU (1) RU2431632C2 (en)
SI (1) SI1992622T1 (en)
TW (1) TWI404709B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008099887A1 (en) 2007-02-16 2008-08-21 Eisai R & D Management Co., Ltd. Crystal, amorphous form and salt of methyl n-[3-(6,7-dimethoxy- 2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid
EP2189450B1 (en) 2007-08-17 2011-12-21 Eisai R&D Management Co., Ltd. Method for producing quinazoline derivative
JP5060561B2 (en) 2007-08-17 2012-10-31 エーザイ・アール・アンド・ディー・マネジメント株式会社 New topical preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR015966A1 (en) * 1997-10-17 2001-05-30 Smithkline Beecham Corp USE OF A PDE4 INHIBITOR COMPOUND FOR THE PREPARATION OF A USEFUL MEDICINAL PRODUCT FOR PRURITE TREATMENT
JPH11209350A (en) 1998-01-26 1999-08-03 Eisai Co Ltd Nitrogen-containing heterocyclic derivative and medicine containing the same

Also Published As

Publication number Publication date
RU2431632C2 (en) 2011-10-20
RS51969B (en) 2012-02-29
PT1992622E (en) 2011-09-19
TW200812980A (en) 2008-03-16
SI1992622T1 (en) 2011-11-30
KR20080094811A (en) 2008-10-24
CY1112554T1 (en) 2016-02-10
TWI404709B (en) 2013-08-11
DK1992622T3 (en) 2011-09-05
MY146275A (en) 2012-07-31
IL193322A (en) 2014-04-30
BRPI0708098B8 (en) 2021-05-25
JO2726B1 (en) 2013-09-15
ES2368089T3 (en) 2011-11-14
KR101278852B1 (en) 2013-07-01
JP4778550B2 (en) 2011-09-21
BRPI0708098B1 (en) 2019-08-06
HRP20110604T1 (en) 2011-09-30
ATE517875T1 (en) 2011-08-15
NZ569936A (en) 2010-07-30
IL193322A0 (en) 2009-05-04
BRPI0708098A2 (en) 2011-05-17
RU2008137654A (en) 2010-03-27
JPWO2007097317A1 (en) 2009-07-16

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150220