CY1112554T1 - 4- (3-benzoylaminophenyl) -6,7-dimethoxy-2-methyl-quinazoline derivative - Google Patents

4- (3-benzoylaminophenyl) -6,7-dimethoxy-2-methyl-quinazoline derivative

Info

Publication number
CY1112554T1
CY1112554T1 CY20111100969T CY111100969T CY1112554T1 CY 1112554 T1 CY1112554 T1 CY 1112554T1 CY 20111100969 T CY20111100969 T CY 20111100969T CY 111100969 T CY111100969 T CY 111100969T CY 1112554 T1 CY1112554 T1 CY 1112554T1
Authority
CY
Cyprus
Prior art keywords
benzoylaminophenyl
dimethoxy
methyl
quinazoline derivative
optionally substituted
Prior art date
Application number
CY20111100969T
Other languages
Greek (el)
Inventor
Kazuki Miyazaki
Kazutomi Kusano
Yasutaka Takase
Osamu Asano
Manabu Shirato
Hisashi Wakita
Naoto Ishii
Takao Saeki
Original Assignee
Eisai R&D Management Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP07714569A external-priority patent/EP1992622B1/en
Application filed by Eisai R&D Management Co., Ltd filed Critical Eisai R&D Management Co., Ltd
Publication of CY1112554T1 publication Critical patent/CY1112554T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A compound represented by the following formula, salt thereof or hydrate thereof, can effectively relieve itch caused by atopic disesae or the like: wherein R represents hydroxyl, C1-6 alkoxy optionally substituted with C1-6 alkoxy, or amino optionally substituted with C1-6 alkyl.
CY20111100969T 2006-02-21 2011-10-10 4- (3-benzoylaminophenyl) -6,7-dimethoxy-2-methyl-quinazoline derivative CY1112554T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006043273 2006-02-21
EP07714569A EP1992622B1 (en) 2006-02-21 2007-02-20 4-(3-benzoylaminophenyl)-6,7-dimethoxy-2- methylaminoquinazoline derivative

Publications (1)

Publication Number Publication Date
CY1112554T1 true CY1112554T1 (en) 2016-02-10

Family

ID=42137992

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20111100969T CY1112554T1 (en) 2006-02-21 2011-10-10 4- (3-benzoylaminophenyl) -6,7-dimethoxy-2-methyl-quinazoline derivative

Country Status (18)

Country Link
JP (1) JP4778550B2 (en)
KR (1) KR101278852B1 (en)
AT (1) ATE517875T1 (en)
BR (1) BRPI0708098B8 (en)
CY (1) CY1112554T1 (en)
DK (1) DK1992622T3 (en)
ES (1) ES2368089T3 (en)
HK (1) HK1122025A1 (en)
HR (1) HRP20110604T1 (en)
IL (1) IL193322A (en)
JO (1) JO2726B1 (en)
MY (1) MY146275A (en)
NZ (1) NZ569936A (en)
PT (1) PT1992622E (en)
RS (1) RS51969B (en)
RU (1) RU2431632C2 (en)
SI (1) SI1992622T1 (en)
TW (1) TWI404709B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008215411B2 (en) 2007-02-16 2012-11-22 Eisai R & D Management Co., Ltd. Crystal, amorphous form and salt of methyl N-[3-(6,7-dimethoxy- 2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid
WO2009025238A1 (en) 2007-08-17 2009-02-26 Eisai R & D Management Co., Ltd. Method for producing quinazoline derivative
US8513269B2 (en) 2007-08-17 2013-08-20 Eisai R&D Management Co., Ltd. Preparation for external use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR015966A1 (en) * 1997-10-17 2001-05-30 Smithkline Beecham Corp USE OF A PDE4 INHIBITOR COMPOUND FOR THE PREPARATION OF A USEFUL MEDICINAL PRODUCT FOR PRURITE TREATMENT
JPH11209350A (en) 1998-01-26 1999-08-03 Eisai Co Ltd Nitrogen-containing heterocyclic derivative and medicine containing the same

Also Published As

Publication number Publication date
HRP20110604T1 (en) 2011-09-30
TWI404709B (en) 2013-08-11
ATE517875T1 (en) 2011-08-15
RU2431632C2 (en) 2011-10-20
NZ569936A (en) 2010-07-30
KR20080094811A (en) 2008-10-24
BRPI0708098A2 (en) 2011-05-17
RS51969B (en) 2012-02-29
ES2368089T3 (en) 2011-11-14
KR101278852B1 (en) 2013-07-01
MY146275A (en) 2012-07-31
RU2008137654A (en) 2010-03-27
JPWO2007097317A1 (en) 2009-07-16
TW200812980A (en) 2008-03-16
JO2726B1 (en) 2013-09-15
PT1992622E (en) 2011-09-19
JP4778550B2 (en) 2011-09-21
SI1992622T1 (en) 2011-11-30
IL193322A (en) 2014-04-30
IL193322A0 (en) 2009-05-04
BRPI0708098B8 (en) 2021-05-25
BRPI0708098B1 (en) 2019-08-06
DK1992622T3 (en) 2011-09-05
HK1122025A1 (en) 2009-05-08

Similar Documents

Publication Publication Date Title
AR110313A2 (en) DERIVATIVES OF TIAZOL-2-IL-PIRROLIDINA
MY148703A (en) Polycyclic cinnamide derivatives
MY150507A (en) Polycyclic compound
HRP20120323T1 (en) Diarylhydantoin compounds
RS52255B (en) Nalmefene hydrochloride dihydrate
CY1111671T1 (en) Heterocyclic compound
HK1208868A1 (en) Novel ,2-dihydroquinoline derivative having substituted phenylchalcogeno lower alkyl group and ester-introduced phenyl group as substituents 2-
MY158982A (en) Heterocyclic compound
WO2009028629A1 (en) Heterocyclic compound and use thereof
RS53003B (en) C7-fluoro substituted tetracycline compounds
WO2005074603A3 (en) Aminobenzoxazoles as therapeutic agents
BRPI0914772A2 (en) 1,2-disubstituted heterocyclic compounds
MX342064B (en) Novel imidazo-oxazine compound or salt thereof.
WO2008019395A3 (en) Compounds for improving learning and memory
WO2006039250A3 (en) Chemokine-binding heterocyclic compound salts, and methods of use thereof
AU2012310674B2 (en) Radioactive fluorine labeled compound
EA201200891A1 (en) DERIVATIVES 3,4,4A, 10D-TETRAGIDRO-1H-TIOPIRANO [4,3-C] IZOHINOLINA
EA200801366A1 (en) DERIVATIVES 3,6-DIGIDRO-2-OXO-6N-1,3,4-TIADIAZINA
CY1112554T1 (en) 4- (3-benzoylaminophenyl) -6,7-dimethoxy-2-methyl-quinazoline derivative
WO2006078984A3 (en) Uses of methylphenidate derivatives
MY158199A (en) Substituted pyridine compound
RS53747B1 (en) Phenanthrenone compounds, compositions and methods
MX2010013184A (en) Heterocyclic compound.
TW200634000A (en) 2-(pyrazol-1-yl)pyridine derivatives
TW200640934A (en) Eudistomin derivatives