HK1062557A1 - Compositions for delivering bisphosphonates - Google Patents
Compositions for delivering bisphosphonatesInfo
- Publication number
- HK1062557A1 HK1062557A1 HK04105477.7A HK04105477A HK1062557A1 HK 1062557 A1 HK1062557 A1 HK 1062557A1 HK 04105477 A HK04105477 A HK 04105477A HK 1062557 A1 HK1062557 A1 HK 1062557A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- compositions
- bisphosphonates
- delivering
- delivering bisphosphonates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/60—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/44—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/58—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C235/64—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring with carbon atoms of carboxamide groups and singly-bound oxygen atoms, bound in ortho-position to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physical Education & Sports Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27267601P | 2001-03-01 | 2001-03-01 | |
PCT/US2002/006295 WO2002070438A2 (fr) | 2001-03-01 | 2002-03-01 | Compositions permettant l'administration de biophosphonates |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1062557A1 true HK1062557A1 (en) | 2004-11-12 |
Family
ID=23040792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK04105477.7A HK1062557A1 (en) | 2001-03-01 | 2004-07-23 | Compositions for delivering bisphosphonates |
Country Status (14)
Country | Link |
---|---|
US (1) | US7309698B2 (fr) |
EP (1) | EP1372667B1 (fr) |
JP (1) | JP4354698B2 (fr) |
KR (1) | KR20030083725A (fr) |
CN (1) | CN1492763B (fr) |
AU (1) | AU2002254082B2 (fr) |
BR (1) | BR0207871A (fr) |
CA (1) | CA2438848C (fr) |
HK (1) | HK1062557A1 (fr) |
MX (1) | MXPA03007837A (fr) |
NZ (1) | NZ527157A (fr) |
RU (1) | RU2309945C2 (fr) |
WO (1) | WO2002070438A2 (fr) |
ZA (1) | ZA200305606B (fr) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL126318A (en) | 1996-03-29 | 2004-09-27 | Emisphere Tech Inc | Compounds and compositions for delivering active agents and some novel carrier compounds |
US6358504B1 (en) * | 1997-02-07 | 2002-03-19 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US8119159B2 (en) * | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
US20070148228A1 (en) * | 1999-02-22 | 2007-06-28 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
CA2452056C (fr) * | 2001-07-02 | 2011-11-01 | Elan Corporation, Plc. | Compositions de particules de matiere bioactive dispersees dans une matiere encapsulante solide continue |
PL371264A1 (en) * | 2001-12-21 | 2005-06-13 | The Procter & Gamble Company | Method for the treatment of bone disorders |
WO2003072195A2 (fr) * | 2002-02-20 | 2003-09-04 | Eli Lilly And Company | Methode d'administration de molecules peptidiques du type glucagon (glp-1) |
ES2532393T3 (es) * | 2002-05-10 | 2015-03-26 | F. Hoffmann-La Roche Ag | Acidos bisfosfónicos para tratamiento y prevención de osteoporosis |
RU2315603C2 (ru) * | 2002-12-20 | 2008-01-27 | Ф.Хоффманн-Ля Рош Аг | Композиция с высокой дозой ибандроната |
US20060286129A1 (en) * | 2003-12-19 | 2006-12-21 | Emisphere Technologies, Inc. | Oral GLP-1 formulations |
ES2729825T3 (es) * | 2004-05-06 | 2019-11-06 | Emisphere Tech Inc | Formas poliméricas cristalinas de N-[8-(2-hidroxibenzoil)amino]caprilato monosódico |
EP2279732B1 (fr) | 2004-05-14 | 2019-03-20 | Emisphere Technologies, Inc. | Composés et compositions pour la distribution d'agents actifs |
EP1750721A4 (fr) | 2004-05-19 | 2012-10-31 | Emisphere Tech Inc | Formulations topiques à base d'acide cromoglycique |
US20080132527A1 (en) | 2004-05-19 | 2008-06-05 | Emisphere Technologies, Inc. | Compositions For Delivering Acyclovir |
US7645459B2 (en) | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of bisphosphonates |
US7645460B2 (en) * | 2004-05-24 | 2010-01-12 | The Procter & Gamble Company | Dosage forms of risedronate |
US20080286359A1 (en) * | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
US20080287400A1 (en) * | 2004-05-24 | 2008-11-20 | Richard John Dansereau | Low Dosage Forms Of Risedronate Or Its Salts |
BRPI0513101A (pt) * | 2004-07-12 | 2008-04-29 | Emisphere Tech Inc | forma unitária de dosagem para administração bucal, uso da forma unitária de dosagem e método para preparar a forma unitária de dosagem |
JP2008509145A (ja) | 2004-08-03 | 2008-03-27 | エミスフィアー テクノロジーズ インコーポレイテッド | 抗糖尿病性経口インスリン−ビグアニドの組み合わせ |
ES2535311T3 (es) | 2004-12-29 | 2015-05-08 | Emisphere Technologies, Inc. | Formulaciones farmacéuticas de sales de galio |
WO2006076692A1 (fr) | 2005-01-12 | 2006-07-20 | Emisphere Technologies, Inc. | Compositions pour l'administration orale de l'hormone parathyroide |
EP1865935B1 (fr) * | 2005-02-17 | 2011-06-08 | Hadasit Medical Research Services and Development Ltd. | Bisphosphonates pour le traitement de l'endometriose |
WO2007011958A2 (fr) | 2005-07-15 | 2007-01-25 | Emisphere Technologies, Inc. | Formes posologiques intra-buccales de glucagon |
US20070049557A1 (en) * | 2005-08-24 | 2007-03-01 | Hashim Ahmed | Solid pharmaceutical dosage forms comprising bisphosphonates and modified amino acid carriers |
CN101437522A (zh) * | 2006-04-07 | 2009-05-20 | 默里昂研究Ⅲ有限公司 | 包含增强剂的固体口服剂型 |
WO2007121318A2 (fr) | 2006-04-12 | 2007-10-25 | Emisphere Technologies, Inc. | Préparations destinées à l'administration d'insuline |
US8771712B2 (en) | 2006-05-09 | 2014-07-08 | Emisphere Technologies, Inc. | Topical administration of acyclovir |
WO2008003050A2 (fr) | 2006-06-28 | 2008-01-03 | Emisphere Technologies, Inc. | Formulations de nitrate de gallium |
US20080139514A1 (en) * | 2006-11-29 | 2008-06-12 | Subhash Pandurang Gore | Diphosphonic acid pharmaceutical compositions |
EP3050568B1 (fr) | 2007-03-13 | 2020-12-02 | JDS Therapeutics, LLC | Procédés et compositions pour la libération prolongée de chrome |
WO2009002867A2 (fr) | 2007-06-26 | 2008-12-31 | Nutrition 21, Inc. | Forme posologique à unités multiples contenant un agent thérapeutique en combinaison avec un complément alimentaire |
WO2009137078A1 (fr) * | 2008-05-07 | 2009-11-12 | Merrion Research Iii Limited | Compositions de peptides et leurs procédés de préparation |
EP2400851A4 (fr) * | 2009-02-25 | 2012-09-05 | Merrion Res Iii Ltd | Composition contenant un bisphosphonate et administration d'un médicament à base de bisphosphonate |
US9169279B2 (en) | 2009-07-31 | 2015-10-27 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
WO2011014766A2 (fr) | 2009-07-31 | 2011-02-03 | Thar Pharmaceuticals, Inc. | Procédé de cristallisation et biodisponibilité |
WO2011017346A2 (fr) | 2009-08-03 | 2011-02-10 | Emisphere Technologies, Inc. | Composition de naproxène à action rapide avec effets gastro-intestinaux réduits |
US8882740B2 (en) * | 2009-12-23 | 2014-11-11 | Stryker Trauma Gmbh | Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone |
US20110182985A1 (en) * | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
WO2011120033A1 (fr) * | 2010-03-26 | 2011-09-29 | Merrion Research Iii Limited | Compositions pharmaceutiques d'inhibiteurs de facteur xa sélectifs destinées à une administration orale |
US9340565B2 (en) | 2010-11-24 | 2016-05-17 | Thar Pharmaceuticals, Inc. | Crystalline forms |
EP2661273A4 (fr) | 2011-01-07 | 2014-06-04 | Merrion Res Iii Ltd | Compositions pharmaceutiques de fer pour administration orale |
CN105749253A (zh) | 2011-03-01 | 2016-07-13 | Jds治疗有限公司 | 用于预防和治疗糖尿病、低血糖症及相关病症的胰岛素和铬组合物 |
US9993427B2 (en) | 2013-03-14 | 2018-06-12 | Biorest Ltd. | Liposome formulation and manufacture |
CN107205948B (zh) | 2015-01-29 | 2021-12-14 | 诺和诺德股份有限公司 | 包含glp-1激动剂和肠溶衣的片剂 |
US11865121B2 (en) | 2016-02-11 | 2024-01-09 | Nutrition21, LLC | Chromium containing compositions for improving health and fitness |
WO2017208070A1 (fr) | 2016-05-31 | 2017-12-07 | Grünenthal GmbH | Acide bisphosphonique et coformeurs avec lysine, glycine, nicotinamide pour le traitement de la polyarthrite psoriasique |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1187828B (it) * | 1985-05-24 | 1987-12-23 | Gentili Ist Spa | Composizione farmaceutica a base di difosfonati per il trattamento dell aretrosi |
US5650386A (en) * | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
US5866536A (en) * | 1995-03-31 | 1999-02-02 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
CN1151836C (zh) * | 1995-03-31 | 2004-06-02 | 艾米斯菲尔技术有限公司 | 用作传送活性剂的化合物和组合物 |
US5616571A (en) * | 1995-06-06 | 1997-04-01 | Merck & Co., Inc. | Bisphosphonates prevent bone loss associated with immunosuppressive therapy |
IL126318A (en) * | 1996-03-29 | 2004-09-27 | Emisphere Tech Inc | Compounds and compositions for delivering active agents and some novel carrier compounds |
US5776888A (en) * | 1997-02-07 | 1998-07-07 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
US5773647A (en) * | 1997-02-07 | 1998-06-30 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
WO2000006184A1 (fr) * | 1998-07-27 | 2000-02-10 | Emisphere Technologies, Inc. | Administration de substances actives par la voie pulmonaire |
AU3378100A (en) * | 1999-02-26 | 2000-09-14 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
SE9901272D0 (sv) | 1999-04-09 | 1999-04-09 | Astra Ab | New improved formulation |
MXPA02004092A (es) | 1999-11-05 | 2003-02-12 | Emisphere Tech Inc | Compuestos y composiciones de acido fenilaminocarboxilico para administrar agentes activos. |
JP4850379B2 (ja) * | 1999-12-16 | 2012-01-11 | エミスフェアー・テクノロジーズ・インク | 活性剤を輸送するための化合物及び組成物 |
AU2001281483A1 (en) * | 2000-03-21 | 2001-10-03 | Emisphere Technologies, Inc. | Method of preparing alkylated salicylamides via a dicarboxylate intermediate |
US7495030B2 (en) * | 2000-09-06 | 2009-02-24 | Emisphere Technologies, Inc. | (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents |
-
2002
- 2002-03-01 CA CA2438848A patent/CA2438848C/fr not_active Expired - Fee Related
- 2002-03-01 WO PCT/US2002/006295 patent/WO2002070438A2/fr active IP Right Grant
- 2002-03-01 MX MXPA03007837A patent/MXPA03007837A/es active IP Right Grant
- 2002-03-01 AU AU2002254082A patent/AU2002254082B2/en not_active Ceased
- 2002-03-01 CN CN02805184XA patent/CN1492763B/zh not_active Expired - Fee Related
- 2002-03-01 EP EP02723294.1A patent/EP1372667B1/fr not_active Expired - Lifetime
- 2002-03-01 NZ NZ527157A patent/NZ527157A/xx not_active IP Right Cessation
- 2002-03-01 RU RU2003129165/04A patent/RU2309945C2/ru not_active IP Right Cessation
- 2002-03-01 BR BR0207871-6A patent/BR0207871A/pt not_active IP Right Cessation
- 2002-03-01 JP JP2002569763A patent/JP4354698B2/ja not_active Expired - Fee Related
- 2002-03-01 US US10/468,622 patent/US7309698B2/en not_active Expired - Fee Related
- 2002-03-01 KR KR10-2003-7011431A patent/KR20030083725A/ko not_active Application Discontinuation
-
2003
- 2003-07-21 ZA ZA200305606A patent/ZA200305606B/en unknown
-
2004
- 2004-07-23 HK HK04105477.7A patent/HK1062557A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2002070438A2 (fr) | 2002-09-12 |
JP2004528303A (ja) | 2004-09-16 |
MXPA03007837A (es) | 2004-03-16 |
KR20030083725A (ko) | 2003-10-30 |
BR0207871A (pt) | 2004-06-22 |
US20040147484A1 (en) | 2004-07-29 |
US7309698B2 (en) | 2007-12-18 |
CN1492763B (zh) | 2012-05-23 |
EP1372667A4 (fr) | 2007-03-14 |
ZA200305606B (en) | 2004-08-25 |
CN1492763A (zh) | 2004-04-28 |
NZ527157A (en) | 2005-04-29 |
EP1372667B1 (fr) | 2014-10-15 |
CA2438848A1 (fr) | 2002-09-12 |
EP1372667A2 (fr) | 2004-01-02 |
RU2003129165A (ru) | 2005-03-27 |
WO2002070438A3 (fr) | 2003-04-24 |
AU2002254082B2 (en) | 2007-05-24 |
RU2309945C2 (ru) | 2007-11-10 |
CA2438848C (fr) | 2011-05-03 |
JP4354698B2 (ja) | 2009-10-28 |
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PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20170301 |