HK1052864A1 - Use of pdgf receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy - Google Patents
Use of pdgf receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathyInfo
- Publication number
- HK1052864A1 HK1052864A1 HK03103784A HK03103784A HK1052864A1 HK 1052864 A1 HK1052864 A1 HK 1052864A1 HK 03103784 A HK03103784 A HK 03103784A HK 03103784 A HK03103784 A HK 03103784A HK 1052864 A1 HK1052864 A1 HK 1052864A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- sub
- treatment
- tyrosine kinase
- receptor tyrosine
- diabetic nephropathy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00810181 | 2000-03-03 | ||
PCT/EP2001/002340 WO2001064200A2 (en) | 2000-03-03 | 2001-03-01 | Use of pdgf receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1052864A1 true HK1052864A1 (en) | 2003-10-03 |
Family
ID=8174580
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03103784A HK1052864A1 (en) | 2000-03-03 | 2003-05-27 | Use of pdgf receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy |
Country Status (11)
Country | Link |
---|---|
US (1) | US7087608B2 (xx) |
EP (1) | EP1259242B1 (xx) |
JP (1) | JP2003525240A (xx) |
AT (1) | ATE369860T1 (xx) |
AU (2) | AU4832401A (xx) |
CA (1) | CA2401812C (xx) |
DE (1) | DE60129934T2 (xx) |
ES (1) | ES2291306T3 (xx) |
HK (1) | HK1052864A1 (xx) |
PT (1) | PT1259242E (xx) |
WO (1) | WO2001064200A2 (xx) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003000186A2 (en) | 2001-06-21 | 2003-01-03 | Ariad Pharmaceuticals, Inc. | Novel phenylamino-pyrimidines and uses thereof |
CA2452392A1 (en) | 2001-06-29 | 2003-01-16 | Ab Science | Use of tyrosine kinase inhibitors for treating inflammatory bowel diseases (ibd) |
WO2003002106A2 (en) | 2001-06-29 | 2003-01-09 | Ab Science | Use of tyrosine kinase inhibitions for treating allergic diseases |
PT1401415E (pt) | 2001-06-29 | 2006-09-29 | Ab Science | Utilizacao de derivados de n-fenil-2-pirimidino-amina para o tratamento de doencas inflamatorias |
EP1434991B1 (en) | 2001-06-29 | 2007-10-17 | AB Science | New potent, selective and non toxic c-kit inhibitors |
PL369123A1 (en) * | 2001-08-25 | 2005-04-18 | Arakis Ltd. | The use of anthroquinones in the treatment of kidney disease |
US7332330B2 (en) * | 2001-09-11 | 2008-02-19 | Renamed Biologics, Inc. | Device for maintaining vascularization near an implant |
WO2003057165A2 (en) | 2002-01-04 | 2003-07-17 | The Rockefeller University | COMPOSITIONS AND METHODS FOR PREVENTION AND TREATMENT OF AMYLOID-β PEPTIDE-RELATED DISORDERS |
US20050261283A1 (en) * | 2002-05-13 | 2005-11-24 | Vikas Sukhatme | Methods and compositions for the treatment of graft failure |
US8450302B2 (en) | 2002-08-02 | 2013-05-28 | Ab Science | 2-(3-aminoaryl) amino-4-aryl-thiazoles and their use as c-kit inhibitors |
JP4726486B2 (ja) | 2002-08-02 | 2011-07-20 | アブ サイエンス | 2−(3−アミノアリール)アミノ−4−アリール−チアゾールおよびそれらのc−kit阻害薬としての使用法 |
GB0222514D0 (en) | 2002-09-27 | 2002-11-06 | Novartis Ag | Organic compounds |
KR101102229B1 (ko) * | 2003-05-27 | 2012-01-05 | 닐스 리차드 웰쉬 | 당뇨병을 치료하기 위한 티로신 키나제 억제제의 용도 |
WO2005016323A2 (en) * | 2003-08-15 | 2005-02-24 | Ab Science | Use of c-kit inhibitors for treating type ii diabetes |
KR20170104639A (ko) | 2003-11-17 | 2017-09-15 | 노파르티스 아게 | 디펩티딜 펩티다제 ⅳ 억제제의 용도 |
WO2008093246A2 (en) | 2007-02-02 | 2008-08-07 | Vegenics Limited | Vegf receptor antagonist for treating organ transplant alloimmunity and arteriosclerosis |
MX353308B (es) | 2008-05-21 | 2018-01-08 | Ariad Pharma Inc | Derivados fosforosos como inhibidores de cinasa. |
US9273077B2 (en) | 2008-05-21 | 2016-03-01 | Ariad Pharmaceuticals, Inc. | Phosphorus derivatives as kinase inhibitors |
SG178279A1 (en) | 2009-08-05 | 2012-03-29 | Intra Cellular Therapies Inc | Novel regulatory proteins and inhibitors |
CA2832504C (en) | 2011-05-04 | 2019-10-01 | Ariad Pharmaceuticals, Inc. | Compounds for inhibiting cell proliferation in egfr-driven cancers |
JP6469567B2 (ja) | 2012-05-05 | 2019-02-13 | アリアド・ファーマシューティカルズ・インコーポレイテッド | Egfr発動性がんの細胞増殖阻害用化合物 |
US9611283B1 (en) | 2013-04-10 | 2017-04-04 | Ariad Pharmaceuticals, Inc. | Methods for inhibiting cell proliferation in ALK-driven cancers |
CN107573322A (zh) * | 2017-09-06 | 2018-01-12 | 南京优科生物医药研究有限公司 | 伊马替尼双氮氧化物、其制备方法和用途 |
EA202192575A1 (ru) | 2019-03-21 | 2022-01-14 | Онксео | Соединения dbait в сочетании с ингибиторами киназ для лечения рака |
US20220229072A1 (en) | 2019-06-04 | 2022-07-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of cd9 as a biomarker and as a biotarget in glomerulonephritis or glomerulosclerosis |
JP2023500906A (ja) | 2019-11-08 | 2023-01-11 | インサーム(インスティテュ ナシオナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシェ メディカル) | キナーゼ阻害剤に対する獲得抵抗性を有するがんの処置方法 |
WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5093330A (en) | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
JP2602735B2 (ja) * | 1989-09-27 | 1997-04-23 | 株式会社大塚製薬工場 | 抗活性酸素剤 |
TW225528B (xx) | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
JP3810020B2 (ja) | 1993-04-22 | 2006-08-16 | 武田薬品工業株式会社 | 腎疾患の予防または治療剤 |
US5795910A (en) | 1994-10-28 | 1998-08-18 | Cor Therapeutics, Inc. | Method and compositions for inhibiting protein kinases |
US5721277A (en) | 1995-04-21 | 1998-02-24 | Sugen, Inc. | Compounds and methods for inhibiting hyper-proliferative cell growth |
CA2214393A1 (en) | 1996-09-02 | 1998-03-02 | Takeda Chemical Industries, Ltd. | Tricyclic compounds, their production and use |
JPH10182644A (ja) * | 1996-11-01 | 1998-07-07 | Takeda Chem Ind Ltd | 三環性化合物、その製造法及び剤 |
CO4950519A1 (es) | 1997-02-13 | 2000-09-01 | Novartis Ag | Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion |
CO4940418A1 (es) | 1997-07-18 | 2000-07-24 | Novartis Ag | Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso |
GB9809869D0 (en) | 1998-05-09 | 1998-07-08 | Medical Res Council | Inhibition of protein kinases |
PT1105136E (pt) | 1998-08-13 | 2007-12-03 | Novartis Ag | Método para tratar doenças oculares neovasculares |
-
2001
- 2001-01-03 US US10/220,214 patent/US7087608B2/en not_active Expired - Fee Related
- 2001-03-01 AU AU4832401A patent/AU4832401A/xx active Pending
- 2001-03-01 WO PCT/EP2001/002340 patent/WO2001064200A2/en active IP Right Grant
- 2001-03-01 DE DE60129934T patent/DE60129934T2/de not_active Expired - Lifetime
- 2001-03-01 ES ES01921298T patent/ES2291306T3/es not_active Expired - Lifetime
- 2001-03-01 AT AT01921298T patent/ATE369860T1/de active
- 2001-03-01 PT PT01921298T patent/PT1259242E/pt unknown
- 2001-03-01 JP JP2001563097A patent/JP2003525240A/ja not_active Ceased
- 2001-03-01 AU AU2001248324A patent/AU2001248324B2/en not_active Ceased
- 2001-03-01 EP EP01921298A patent/EP1259242B1/en not_active Expired - Lifetime
- 2001-03-01 CA CA002401812A patent/CA2401812C/en not_active Expired - Fee Related
-
2003
- 2003-05-27 HK HK03103784A patent/HK1052864A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1259242B1 (en) | 2007-08-15 |
CA2401812C (en) | 2009-06-09 |
WO2001064200A3 (en) | 2002-01-17 |
DE60129934D1 (de) | 2007-09-27 |
ES2291306T3 (es) | 2008-03-01 |
AU2001248324B2 (en) | 2005-09-15 |
JP2003525240A (ja) | 2003-08-26 |
WO2001064200A2 (en) | 2001-09-07 |
CA2401812A1 (en) | 2001-09-07 |
EP1259242A2 (en) | 2002-11-27 |
US7087608B2 (en) | 2006-08-08 |
ATE369860T1 (de) | 2007-09-15 |
AU4832401A (en) | 2001-09-12 |
DE60129934T2 (de) | 2008-05-08 |
PT1259242E (pt) | 2007-11-15 |
US20030186977A1 (en) | 2003-10-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20140301 |