HK1043945B - 含氯雷他定和偽麻黃碱的藥物膠囊組合物 - Google Patents

含氯雷他定和偽麻黃碱的藥物膠囊組合物

Info

Publication number
HK1043945B
HK1043945B HK02105460.8A HK02105460A HK1043945B HK 1043945 B HK1043945 B HK 1043945B HK 02105460 A HK02105460 A HK 02105460A HK 1043945 B HK1043945 B HK 1043945B
Authority
HK
Hong Kong
Prior art keywords
pseudoephedrine
pellets
pharmaceutically acceptable
loratadine
pharmaceutical capsule
Prior art date
Application number
HK02105460.8A
Other languages
English (en)
Other versions
HK1043945A1 (en
Inventor
趙恆範
朴映準
金賢洙
Original Assignee
株式會社柳韓洋行
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式會社柳韓洋行 filed Critical 株式會社柳韓洋行
Publication of HK1043945A1 publication Critical patent/HK1043945A1/xx
Publication of HK1043945B publication Critical patent/HK1043945B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
HK02105460.8A 1999-02-23 2002-07-24 含氯雷他定和偽麻黃碱的藥物膠囊組合物 HK1043945B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19990005873 1999-02-23
PCT/KR2000/000130 WO2000050015A1 (en) 1999-02-23 2000-02-18 Pharmaceutical capsule compositions containing loratadine and pseudoephedrine

Publications (2)

Publication Number Publication Date
HK1043945A1 HK1043945A1 (en) 2002-10-04
HK1043945B true HK1043945B (zh) 2005-02-08

Family

ID=19574799

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02105460.8A HK1043945B (zh) 1999-02-23 2002-07-24 含氯雷他定和偽麻黃碱的藥物膠囊組合物

Country Status (10)

Country Link
US (1) US6251427B1 (zh)
EP (1) EP1154762B1 (zh)
JP (1) JP3645816B2 (zh)
CN (1) CN1161112C (zh)
AT (1) ATE253354T1 (zh)
AU (1) AU2697100A (zh)
DE (1) DE60006362T2 (zh)
ES (1) ES2204517T3 (zh)
HK (1) HK1043945B (zh)
WO (1) WO2000050015A1 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506783B1 (en) * 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6555139B2 (en) 1999-06-28 2003-04-29 Wockhardt Europe Limited Preparation of micron-size pharmaceutical particles by microfluidization
WO2001021161A2 (en) * 1999-09-21 2001-03-29 Schering Corporation Use of desloratadine for treating allergic and inflammatory conditions
CN1518448A (zh) * 2001-06-20 2004-08-04 ���鹫˾ 用于治疗鼻充血和鼻塞的抗组胺剂
FR2830447B1 (fr) * 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
MXPA04009968A (es) 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de principio (s) activo (s).
US20040033257A1 (en) * 2002-05-30 2004-02-19 Strides Inc. Pharmaceutical formulation in a drug delivery system and process for preparing the same
PE20050202A1 (es) * 2003-05-12 2005-05-14 Dasan Medichen Co Ltd La composicion farmaceutica de liberacion controlada de pseudoefredina o sus sales
DK1660047T3 (en) 2003-08-13 2014-03-10 Biocon Ltd MICROPARTICALLY FATIC ACID SALT SOLID DOSAGE FORMS FOR THERAPEUTIC AGENTS
CA2537477C (en) * 2003-09-03 2013-05-14 Boehringer Ingelheim International Gmbh Capsules containing active substance pellets with different release profiles
US20070190125A1 (en) 2004-03-03 2007-08-16 Constantine Georgiades Positioning feature for aiding use of film or strip product
PE20080313A1 (es) * 2006-06-01 2008-04-10 Schering Corp Formulaciones de liberacion pulsada de fenilefrina y composiciones farmaceuticas
NZ573173A (en) 2006-06-01 2012-03-30 Msd Consumer Care Inc Phenylephrine pharmaceutical formulation and compositions for colonic absorption
BRPI0712960A2 (pt) * 2006-06-30 2012-04-17 Teva Pharma compostos farmacêuticos que incluem uma combinação de piperidinoalcanol e descongestionante
JP5668317B2 (ja) * 2009-04-24 2015-02-12 大正製薬株式会社 プソイドエフェドリン含有製剤粒子
US20110218209A1 (en) * 2010-03-06 2011-09-08 Paul Daniel Yered Nutrient delievry drug composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2738303A (en) * 1952-07-18 1956-03-13 Smith Kline French Lab Sympathomimetic preparation
US4173626A (en) * 1978-12-11 1979-11-06 Merck & Co., Inc. Sustained release indomethacin
US5314697A (en) * 1992-10-23 1994-05-24 Schering Corporation Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
KR960006917A (ko) 1994-08-13 1996-03-22 김태훈 테르페나딘과-염산슈도에페드린 복합 펠렛(pellet) 조성물
WO1998018470A1 (en) * 1996-10-31 1998-05-07 Schering Corporation Composition, for the treatment of asthma, containing loratadine and a decongestant
US5840329A (en) * 1997-05-15 1998-11-24 Bioadvances Llc Pulsatile drug delivery system

Also Published As

Publication number Publication date
DE60006362D1 (de) 2003-12-11
JP2002537323A (ja) 2002-11-05
DE60006362T2 (de) 2004-08-26
WO2000050015A1 (en) 2000-08-31
ES2204517T3 (es) 2004-05-01
CN1161112C (zh) 2004-08-11
HK1043945A1 (en) 2002-10-04
JP3645816B2 (ja) 2005-05-11
CN1341014A (zh) 2002-03-20
AU2697100A (en) 2000-09-14
US6251427B1 (en) 2001-06-26
ATE253354T1 (de) 2003-11-15
EP1154762B1 (en) 2003-11-05
EP1154762A1 (en) 2001-11-21

Similar Documents

Publication Publication Date Title
HK1043945A1 (en) Pharmaceutical capsule compositions containing loratadine and pseudoephedrine.
IL111647A (en) Pharmaceutical compositions comprising microencapsulated 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles and their preparation
EP2266542A3 (en) Controlled release nanoparticulate compositions
CA2264238A1 (fr) Forme galenique a liberation prolongee de milnacipran
UA88056C2 (uk) Дозована форма оксикодону, що вводиться один раз на день
EP2036558A3 (en) Orally administrable opioid formulations having extended duration of effect
AU7143796A (en) Controlled release matrix for pharmaceuticals
NZ311145A (en) Controlled release formulations containing a poorly soluble drug in a solid dispersion with a hydrophilic poloxamer
IE831799L (en) Controlled release naproxen and naproxen sodium tablets.
IL119684A (en) Long lasting release nifedipine preparation in form of press coated tablets
CA2126611A1 (en) Opiod Formulations Having Extended Controlled Release
DK0923934T3 (da) Modified release-matrixformulering af cefaclor og cephalexin
ES8502333A1 (es) Un procedimiento para la preparacion de una tableta farmaceutica
WO2004108162A3 (en) Controlled release pharmaceutical composition
CZ225596A3 (en) Film-coated tablets of paracetamol and domperidon
PT885014E (pt) Composicoes farmaceuticas contendo polimeros orto ester tamponados
CA2240281A1 (en) Modified release oral pharmaceutical composition containing 5-asa and method for the treatment of bowel diseases
DE60035579D1 (de) Multipartikuläre arzneizusammensetzungen mit gesteuerter wirkstoffabgabe enthaltend selektive inhibitoren der serotoninwiederaufnahme
WO2006011001A3 (en) Controlled release compositions of divalproex sodium
CA2243988A1 (en) Pharmaceutical compositions containing buffered ortho ester polymers

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080218