HK1043367A1 - Benzoylguanidine derivatives with advantageous properties, method for producing them and their use in the production of medicaments. - Google Patents
Benzoylguanidine derivatives with advantageous properties, method for producing them and their use in the production of medicaments.Info
- Publication number
- HK1043367A1 HK1043367A1 HK02105065A HK02105065A HK1043367A1 HK 1043367 A1 HK1043367 A1 HK 1043367A1 HK 02105065 A HK02105065 A HK 02105065A HK 02105065 A HK02105065 A HK 02105065A HK 1043367 A1 HK1043367 A1 HK 1043367A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- medicaments
- producing
- production
- advantageous properties
- benzoylguanidine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843489A DE19843489B4 (en) | 1998-09-22 | 1998-09-22 | Benzoylguanidine derivatives having advantageous properties, processes for their preparation and their use in the preparation of medicaments, and pharmaceutical compositions containing them |
| PCT/EP1999/006857 WO2000017176A2 (en) | 1998-09-22 | 1999-09-16 | Benzoylguanidine derivatives with advantageous properties, method for producing them and their use in the production of medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HK1043367A1 true HK1043367A1 (en) | 2002-09-13 |
| HK1043367B HK1043367B (en) | 2005-02-25 |
Family
ID=7881872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK02105065.7A HK1043367B (en) | 1998-09-22 | 2002-07-08 | Benzoylguanidine derivatives with advantageous properties, method for producing them and their use in the production of medicaments |
Country Status (35)
| Country | Link |
|---|---|
| EP (1) | EP1165534B1 (en) |
| JP (1) | JP3817425B2 (en) |
| KR (1) | KR100621821B1 (en) |
| CN (1) | CN1166654C (en) |
| AR (1) | AR023668A1 (en) |
| AT (1) | ATE288425T1 (en) |
| AU (1) | AU764819C (en) |
| BG (1) | BG64985B1 (en) |
| BR (1) | BR9913107A (en) |
| CA (1) | CA2345006C (en) |
| CO (1) | CO5150207A1 (en) |
| CZ (1) | CZ300158B6 (en) |
| DE (2) | DE19843489B4 (en) |
| EA (1) | EA004687B1 (en) |
| EE (1) | EE04749B1 (en) |
| EG (1) | EG23757A (en) |
| ES (1) | ES2237951T3 (en) |
| HK (1) | HK1043367B (en) |
| HR (1) | HRP20010194B1 (en) |
| HU (1) | HU228955B1 (en) |
| ID (1) | ID27759A (en) |
| IL (1) | IL141805A (en) |
| MY (1) | MY121362A (en) |
| NO (1) | NO317993B1 (en) |
| NZ (1) | NZ511167A (en) |
| PE (1) | PE20001085A1 (en) |
| PL (1) | PL195291B1 (en) |
| PT (1) | PT1165534E (en) |
| RS (1) | RS49971B (en) |
| SA (1) | SA99200474B1 (en) |
| SK (1) | SK285578B6 (en) |
| TR (1) | TR200100801T2 (en) |
| TW (1) | TWI221841B (en) |
| WO (1) | WO2000017176A2 (en) |
| ZA (1) | ZA200101212B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10106970A1 (en) * | 2001-02-15 | 2002-08-29 | Boehringer Ingelheim Pharma | New benzoylguanidine salt |
| US6730678B2 (en) * | 2001-02-15 | 2004-05-04 | Boehringer Ingelheim Pharma Kg | Benzoylguanidine salt and hydrates thereof |
| US6982256B2 (en) | 2001-09-07 | 2006-01-03 | Boehringer Ingelheim Pharma Kg | Tolerance of 4-(4-(2-pyrrolylcarbonyl)-1-piperazinyl)-3-trifluoromethyl-benzoylguanidine in intravenous administration |
| DE10144030A1 (en) * | 2001-09-07 | 2003-03-27 | Boehringer Ingelheim Pharma | Composition containing 4-piperazino-benzoylguanidine derivative, useful e.g. for treating cardiac infarction, containing component to improve local tolerance, e.g. beta-cyclodextrin derivative or polymer |
| FR2871157A1 (en) * | 2004-06-04 | 2005-12-09 | Aventis Pharma Sa | BIARYL AROMATIC PRODUCTS, COMPOSITIONS CONTAINING SAME AND USE THEREOF |
| CA2730116A1 (en) * | 2008-07-08 | 2010-01-14 | Boehringer Ingelheim International Gmbh | Pyrrolidinyl and piperidinyl compounds useful as nhe-1 inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19601303A1 (en) * | 1996-01-16 | 1997-07-17 | Boehringer Ingelheim Kg | Novel benzoylguanidine derivatives, process for their preparation and their use in the manufacture of medicaments |
-
1998
- 1998-09-22 DE DE19843489A patent/DE19843489B4/en not_active Expired - Fee Related
-
1999
- 1999-08-17 SA SA99200474A patent/SA99200474B1/en unknown
- 1999-09-16 EE EEP200100178A patent/EE04749B1/en not_active IP Right Cessation
- 1999-09-16 EA EA200100317A patent/EA004687B1/en not_active IP Right Cessation
- 1999-09-16 PT PT99952453T patent/PT1165534E/en unknown
- 1999-09-16 DE DE59911568T patent/DE59911568D1/en not_active Expired - Lifetime
- 1999-09-16 WO PCT/EP1999/006857 patent/WO2000017176A2/en active IP Right Grant
- 1999-09-16 EP EP99952453A patent/EP1165534B1/en not_active Expired - Lifetime
- 1999-09-16 RS YUP-215/01A patent/RS49971B/en unknown
- 1999-09-16 CZ CZ20011047A patent/CZ300158B6/en not_active IP Right Cessation
- 1999-09-16 CA CA002345006A patent/CA2345006C/en not_active Expired - Fee Related
- 1999-09-16 TR TR2001/00801T patent/TR200100801T2/en unknown
- 1999-09-16 ID IDW20010663A patent/ID27759A/en unknown
- 1999-09-16 SK SK396-2001A patent/SK285578B6/en not_active IP Right Cessation
- 1999-09-16 AU AU64659/99A patent/AU764819C/en not_active Ceased
- 1999-09-16 HU HU0200225A patent/HU228955B1/en not_active IP Right Cessation
- 1999-09-16 ES ES99952453T patent/ES2237951T3/en not_active Expired - Lifetime
- 1999-09-16 CN CNB998111430A patent/CN1166654C/en not_active Expired - Fee Related
- 1999-09-16 BR BR9913107-2A patent/BR9913107A/en not_active IP Right Cessation
- 1999-09-16 AT AT99952453T patent/ATE288425T1/en active
- 1999-09-16 PL PL99347234A patent/PL195291B1/en unknown
- 1999-09-16 IL IL14180599A patent/IL141805A/en not_active IP Right Cessation
- 1999-09-16 KR KR1020017003627A patent/KR100621821B1/en not_active IP Right Cessation
- 1999-09-16 JP JP2000574086A patent/JP3817425B2/en not_active Expired - Fee Related
- 1999-09-16 NZ NZ511167A patent/NZ511167A/en not_active IP Right Cessation
- 1999-09-20 MY MYPI99004064A patent/MY121362A/en unknown
- 1999-09-20 PE PE1999000949A patent/PE20001085A1/en not_active Application Discontinuation
- 1999-09-21 CO CO99059852A patent/CO5150207A1/en unknown
- 1999-09-22 EG EG118099A patent/EG23757A/en active
- 1999-09-22 AR ARP990104775A patent/AR023668A1/en not_active Ceased/Invalidation/Refusal/Rejection/Nullification
- 1999-09-22 TW TW088116279A patent/TWI221841B/en not_active IP Right Cessation
-
2001
- 2001-02-13 ZA ZA200101212A patent/ZA200101212B/en unknown
- 2001-03-09 BG BG105326A patent/BG64985B1/en active Active
- 2001-03-15 HR HR20010194A patent/HRP20010194B1/en not_active IP Right Cessation
- 2001-03-21 NO NO20011428A patent/NO317993B1/en not_active IP Right Cessation
-
2002
- 2002-07-08 HK HK02105065.7A patent/HK1043367B/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20100916 |