HK1042319B - 合成gagpol基因及其應用 - Google Patents

合成gagpol基因及其應用

Info

Publication number
HK1042319B
HK1042319B HK02103411.3A HK02103411A HK1042319B HK 1042319 B HK1042319 B HK 1042319B HK 02103411 A HK02103411 A HK 02103411A HK 1042319 B HK1042319 B HK 1042319B
Authority
HK
Hong Kong
Prior art keywords
gagpol genes
synthetic
genes
synthetic gagpol
generation
Prior art date
Application number
HK02103411.3A
Other languages
English (en)
Other versions
HK1042319A1 (en
Inventor
Ralf Wagner
Markus Graf
Ludwig Deml
Kurt Bieler
Original Assignee
Geneart Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8168767&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1042319(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geneart Ag filed Critical Geneart Ag
Publication of HK1042319A1 publication Critical patent/HK1042319A1/xx
Publication of HK1042319B publication Critical patent/HK1042319B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK02103411.3A 2000-05-18 2002-05-06 合成gagpol基因及其應用 HK1042319B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00110623A EP1156112B1 (en) 2000-05-18 2000-05-18 Synthetic gagpol genes and their uses

Publications (2)

Publication Number Publication Date
HK1042319A1 HK1042319A1 (en) 2002-08-09
HK1042319B true HK1042319B (zh) 2006-10-20

Family

ID=8168767

Family Applications (2)

Application Number Title Priority Date Filing Date
HK02103411.3A HK1042319B (zh) 2000-05-18 2002-05-06 合成gagpol基因及其應用
HK03105174A HK1053853A1 (en) 2000-05-18 2003-07-17 Sythetic gagpol genes and their uses

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK03105174A HK1053853A1 (en) 2000-05-18 2003-07-17 Sythetic gagpol genes and their uses

Country Status (10)

Country Link
US (3) US7378515B2 (zh)
EP (2) EP1156112B1 (zh)
CN (1) CN1429270A (zh)
AT (2) ATE318908T1 (zh)
AU (1) AU2001281781A1 (zh)
BR (1) BR0110706A (zh)
CA (1) CA2408433A1 (zh)
DE (2) DE60026199T2 (zh)
HK (2) HK1042319B (zh)
WO (1) WO2001088141A2 (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002022080A2 (en) * 2000-09-15 2002-03-21 Merck & Co., Inc. Enhanced first generation adenovirus vaccines expressing codon optimized hiv1-gag, pol, nef and modifications
EP1201750A1 (en) * 2000-10-26 2002-05-02 Genopoietic Synthetic viruses and uses thereof
MXPA04002631A (es) * 2001-09-20 2004-07-08 Glaxo Group Ltd Vacunas de adn optimizadas por codon gag-vih.
ES2429338T3 (es) 2002-12-23 2013-11-14 Vical Incorporated Vacuna basada en polinucleótidos optimizados por codones contra infección por citomegalovirus humano
DE10260805A1 (de) * 2002-12-23 2004-07-22 Geneart Gmbh Verfahren und Vorrichtung zum Optimieren einer Nucleotidsequenz zur Expression eines Proteins
US20050220816A1 (en) * 2004-03-31 2005-10-06 Advanced Bioscience Laboratories, Inc. Mutant viral nucleic acids and vaccine containing same
DE102004037611B4 (de) * 2004-08-03 2013-10-02 Geneart Ag Induzierbare Genexpression
JP4550115B2 (ja) * 2004-08-03 2010-09-22 ジーンアート・アクチエンゲゼルシャフト ＣｐＧ含量を変化させることにより遺伝子発現を調整する方法
ES2281252B1 (es) * 2005-07-27 2009-02-16 Consejo Superior De Investigaciones Cientificas Vectores recombinantes basados en el virus modificado de ankara (mva) como vacunas preventivas y terapeuticas contra el sida.
US8323891B2 (en) * 2008-08-01 2012-12-04 Claflin University miRNA triplex formations for the downregulation of viral replication
CA2793959C (en) 2010-03-25 2019-06-04 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
CA2832109C (en) 2011-06-10 2021-07-06 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
EP2620446A1 (en) 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
CA2865676C (en) 2012-04-17 2020-03-10 Stefan Klostermann Method for the expression of polypeptides using modified nucleic acids
JP2022538178A (ja) 2019-06-28 2022-08-31 エフ．ホフマン－ラ ロシュ アーゲー 抗体の製造方法
CA3161633A1 (en) 2019-11-14 2021-05-20 Aelix Therapeutics, S.L. Dosage regimens for vaccines

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69836206T2 (de) * 1997-02-07 2007-08-23 Merck & Co., Inc. Synthetische hiv gag gene
AU6139699A (en) * 1998-09-11 2000-04-03 Children's Medical Center Corporation Packaging cell lines for hiv-derived retroviral vector particles
WO2000039304A2 (en) * 1998-12-31 2000-07-06 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof

Also Published As

Publication number Publication date
EP1156112B1 (en) 2006-03-01
DE60026199D1 (de) 2006-04-27
EP1156112A1 (en) 2001-11-21
HK1042319A1 (en) 2002-08-09
CA2408433A1 (en) 2001-11-22
DE60121572D1 (de) 2006-08-31
WO2001088141A2 (en) 2001-11-22
ATE333503T1 (de) 2006-08-15
US20070293448A1 (en) 2007-12-20
US7378515B2 (en) 2008-05-27
US20130122585A1 (en) 2013-05-16
HK1053853A1 (en) 2003-11-07
ATE318908T1 (de) 2006-03-15
CN1429270A (zh) 2003-07-09
BR0110706A (pt) 2003-01-28
US20040152069A1 (en) 2004-08-05
EP1282712B1 (en) 2006-07-19
AU2001281781A1 (en) 2001-11-26
WO2001088141A3 (en) 2002-04-18
DE60121572T2 (de) 2007-06-28
DE60026199T2 (de) 2006-11-23
EP1282712A2 (en) 2003-02-12
US8287881B2 (en) 2012-10-16

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Legal Events

Date Code Title Description
PE Patent expired

Effective date: 20200517