HK1041273B - 產生代表特定細胞類型的單克隆抗體的組合物和方法 - Google Patents

產生代表特定細胞類型的單克隆抗體的組合物和方法

Info

Publication number
HK1041273B
HK1041273B HK02102576.6A HK02102576A HK1041273B HK 1041273 B HK1041273 B HK 1041273B HK 02102576 A HK02102576 A HK 02102576A HK 1041273 B HK1041273 B HK 1041273B
Authority
HK
Hong Kong
Prior art keywords
monoclonal antibodies
cell type
present
specific cell
antigens
Prior art date
Application number
HK02102576.6A
Other languages
English (en)
Other versions
HK1041273A1 (en
Inventor
Jennie P Mather
Laura N Bald
Penelope R Roberts
Jean-Philippe F Stephan
Original Assignee
Macrogenics West Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Macrogenics West Inc filed Critical Macrogenics West Inc
Publication of HK1041273A1 publication Critical patent/HK1041273A1/xx
Publication of HK1041273B publication Critical patent/HK1041273B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK02102576.6A 1998-12-22 2002-04-08 產生代表特定細胞類型的單克隆抗體的組合物和方法 HK1041273B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21853998A 1998-12-22 1998-12-22
PCT/US1999/030741 WO2000037503A1 (en) 1998-12-22 1999-12-22 Compositions and methods for generating monoclonal antibodies representative of a specific cell type

Publications (2)

Publication Number Publication Date
HK1041273A1 HK1041273A1 (en) 2002-07-05
HK1041273B true HK1041273B (zh) 2007-05-18

Family

ID=22815514

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102576.6A HK1041273B (zh) 1998-12-22 2002-04-08 產生代表特定細胞類型的單克隆抗體的組合物和方法

Country Status (11)

Country Link
US (1) US20040146990A1 (zh)
EP (1) EP1141026B1 (zh)
JP (2) JP2002538772A (zh)
CN (1) CN1258539C (zh)
AT (1) ATE346865T1 (zh)
AU (1) AU776675B2 (zh)
CA (1) CA2352471A1 (zh)
DE (1) DE69934250T2 (zh)
DK (1) DK1141026T3 (zh)
HK (1) HK1041273B (zh)
WO (1) WO2000037503A1 (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR177400A0 (en) 2000-11-29 2000-12-21 Cancerprobe Pty Ltd Probes for identifying cancer-specific antigens
CA2475356A1 (en) 2002-02-12 2003-08-21 Raven Biotechnologies, Inc. Human fetal bladder-derived epithelial cells
CA2597198C (en) 2005-02-04 2016-06-21 Raven Biotechnologies, Inc. Antibodies that bind to epha2 and methods of use thereof
US20100015638A1 (en) * 2005-03-31 2010-01-21 Susumu Uchiyama Method for production of antibody directed against cell membrane surface antigen epitope and assaying method
JP2009519714A (ja) * 2005-12-16 2009-05-21 マーク ヴァイセンタール、ラリー 内皮細胞を含む微小凝集体
US7943666B2 (en) * 2006-07-24 2011-05-17 Trinity Laboratories, Inc. Esters of capsaicin for treating pain
EP2550529B1 (en) 2010-03-23 2021-11-17 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding
DE102010039018B4 (de) 2010-08-06 2013-02-28 Technische Universität Dresden Anti-La Antikörper und ihre Anwendung zum Immunotargeting
EP2771349B1 (en) 2011-09-16 2020-02-26 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding
EP2965087B1 (en) * 2013-03-06 2018-10-17 General Electric Company Methods of analyzing an h&e stained biological sample
WO2017146127A1 (ja) * 2016-02-24 2017-08-31 積水メディカル株式会社 イムノクロマトグラフィーを利用した癌胎児性フィブロネクチンの検出方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487829A (en) * 1982-03-23 1984-12-11 Massachusetts Institute Of Technology Production and use of monoclonal antibodies against adenoviruses
US5364785A (en) * 1990-02-09 1994-11-15 Genentech, Inc. Method of isolating lung cell line
WO1994011404A1 (en) * 1992-11-19 1994-05-26 Dana-Farber Cancer Institute Antibodies for gm-csf receptor and uses thereof
US5721139A (en) * 1995-05-10 1998-02-24 Genentech, Inc. Isolating and culturing schwann cells
US5714385A (en) * 1995-05-10 1998-02-03 Genentech, Inc. Media for culturing schwann cells
IL122233A (en) * 1996-12-06 2001-04-30 Akzo Nobel Nv Method of generating monoclonal antibodies to cell wall and pharmaceutical preparations and diagnostic agents containing them
US6004528A (en) * 1997-09-18 1999-12-21 Bergstein; Ivan Methods of cancer diagnosis and therapy targeted against the cancer stemline

Also Published As

Publication number Publication date
JP4426627B2 (ja) 2010-03-03
HK1041273A1 (en) 2002-07-05
AU2211300A (en) 2000-07-12
AU776675B2 (en) 2004-09-16
EP1141026B1 (en) 2006-11-29
ATE346865T1 (de) 2006-12-15
JP2002538772A (ja) 2002-11-19
DK1141026T3 (da) 2007-03-26
US20040146990A1 (en) 2004-07-29
CN1350549A (zh) 2002-05-22
DE69934250T2 (de) 2007-05-24
DE69934250D1 (de) 2007-01-11
CA2352471A1 (en) 2000-06-29
JP2009001562A (ja) 2009-01-08
WO2000037503A1 (en) 2000-06-29
EP1141026A1 (en) 2001-10-10
CN1258539C (zh) 2006-06-07

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20121222