HK1038749A1 - 2-piperazino alkylamino benzoazole derivatives: dopamine receptor subtype specific ligands - Google Patents
2-piperazino alkylamino benzoazole derivatives: dopamine receptor subtype specific ligandsInfo
- Publication number
- HK1038749A1 HK1038749A1 HK02100301.2A HK02100301A HK1038749A1 HK 1038749 A1 HK1038749 A1 HK 1038749A1 HK 02100301 A HK02100301 A HK 02100301A HK 1038749 A1 HK1038749 A1 HK 1038749A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- piperazino
- alkylamino
- dopamine receptor
- receptor subtype
- specific ligands
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16357398A | 1998-09-30 | 1998-09-30 | |
| PCT/US1999/022791 WO2000018767A2 (en) | 1998-09-30 | 1999-09-30 | 2-piperazino alkylamino benzoazole derivatives: dopamine receptor subtype specific ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1038749A1 true HK1038749A1 (en) | 2002-03-28 |
Family
ID=22590612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK02100301.2A HK1038749A1 (en) | 1998-09-30 | 2002-01-15 | 2-piperazino alkylamino benzoazole derivatives: dopamine receptor subtype specific ligands |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1117663A2 (en) |
| JP (1) | JP2002525373A (en) |
| CN (1) | CN1325397A (en) |
| AU (1) | AU6280199A (en) |
| CA (1) | CA2345944A1 (en) |
| HK (1) | HK1038749A1 (en) |
| WO (1) | WO2000018767A2 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1303272B1 (en) | 2000-06-21 | 2008-02-13 | F. Hoffmann-La Roche Ag | Benzothiazole derivatives for the treatment of alzheimer's disease and parkinson's disease |
| US6713499B2 (en) * | 2001-12-12 | 2004-03-30 | Hoffman-La Roche Inc. | 7-Amino-benzothiazole derivatives |
| GB0203299D0 (en) * | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel compounds |
| TW200400035A (en) | 2002-03-28 | 2004-01-01 | Glaxo Group Ltd | Novel compounds |
| US7087761B2 (en) | 2003-01-07 | 2006-08-08 | Hoffmann-La Roche Inc. | Cyclization process for substituted benzothiazole derivatives |
| WO2005021547A2 (en) * | 2003-08-28 | 2005-03-10 | Pharmaxis Pty Ltd. | Heterocyclic cannabinoid cb2 receptor antagonists |
| BRPI0415767A (en) * | 2003-10-24 | 2006-12-26 | Hoffmann La Roche | ccr-3 receptor antagonists |
| AU2005247567B2 (en) | 2004-05-24 | 2010-09-02 | F. Hoffmann-La Roche Ag | 4-hydroxy-4-methyl-piperidine-1-carboxylic acid (4-methoxy-7-morpholin-4-yl-benzothiazol-2-yl)-amide |
| FR2877005A1 (en) * | 2004-10-22 | 2006-04-28 | Bioprojet Soc Civ Ile | NEW ARYLPIPERAZINE DERIVATIVES |
| US7459563B2 (en) | 2004-11-05 | 2008-12-02 | Hoffmann-La Roche Inc. | Process for the preparation of isonicotinic acid derivatives |
| BRPI0609719B8 (en) | 2005-03-23 | 2021-05-25 | Hoffmann La Roche | acetylenyl-pyrazole-pyrimidine derivatives as mgbur2 antagonists |
| BRPI0616571A2 (en) | 2005-09-27 | 2011-06-21 | Hoffmann La Roche | oxadiazolyl pyrazol pyridimines as mglur2 antagonists, process for their preparation, pharmaceutical composition containing them and use thereof |
| EP2938597B1 (en) * | 2012-12-27 | 2016-10-26 | Alzprotect | Sulphate salts of n-(3-(4-(3-(diisobutylamino)propyl)piperazin-1-yl)propyl)-1h-benzo[d]imidazol-2-amine, preparation thereof and use of the same |
| CN105753811A (en) * | 2016-03-31 | 2016-07-13 | 湖南工程学院 | Dopamine D4 receptor ligand and preparation method thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9306578D0 (en) * | 1993-03-30 | 1993-05-26 | Merck Sharp & Dohme | Therapeutic agents |
| AU5982696A (en) * | 1995-06-05 | 1996-12-24 | Neurogen Corporation | 1-(n'-(arylalkylaminoalkyl)) aminoisoindoles as dopamine rec eptor ligands |
| TW593290B (en) * | 1996-05-10 | 2004-06-21 | Janssen Pharmaceutica Nv | Alkylaminobenzothiazole and -benzoxazole derivatives |
| EP0991642A1 (en) * | 1997-06-13 | 2000-04-12 | Neurogen Corporation | 2-aminoalkylaminoquinolines as dopamine d4 ligands |
| WO1999023092A2 (en) * | 1997-10-31 | 1999-05-14 | Neurogen Corporation | 3-aminoalkylamino-2h-1,4-benzoxa(thia-)zines and pharmaceutical compositions containing them |
-
1999
- 1999-09-30 CN CN99813074A patent/CN1325397A/en active Pending
- 1999-09-30 WO PCT/US1999/022791 patent/WO2000018767A2/en not_active Application Discontinuation
- 1999-09-30 JP JP2000572226A patent/JP2002525373A/en active Pending
- 1999-09-30 EP EP99950068A patent/EP1117663A2/en not_active Withdrawn
- 1999-09-30 CA CA002345944A patent/CA2345944A1/en not_active Abandoned
- 1999-09-30 AU AU62801/99A patent/AU6280199A/en not_active Abandoned
-
2002
- 2002-01-15 HK HK02100301.2A patent/HK1038749A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000018767A2 (en) | 2000-04-06 |
| JP2002525373A (en) | 2002-08-13 |
| EP1117663A2 (en) | 2001-07-25 |
| WO2000018767A3 (en) | 2000-07-27 |
| WO2000018767A9 (en) | 2001-04-19 |
| CA2345944A1 (en) | 2000-04-06 |
| AU6280199A (en) | 2000-04-17 |
| CN1325397A (en) | 2001-12-05 |
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