GR852098B - - Google Patents

Info

Publication number
GR852098B
GR852098B GR852098A GR850102098A GR852098B GR 852098 B GR852098 B GR 852098B GR 852098 A GR852098 A GR 852098A GR 850102098 A GR850102098 A GR 850102098A GR 852098 B GR852098 B GR 852098B
Authority
GR
Greece
Prior art keywords
collagen
hydroxylase
fibrosuppressants
clq
immunosuppressants
Prior art date
Application number
GR852098A
Other languages
English (en)
Inventor
Volkmar Gunzler
Hartmut Dr Hanauske-Abel
Jurgen Dr Mohr
Georg Dr Tschank
Kari Prof Dr Kivirikko
Kari Dr Majama
Dietrich Dr Brocks
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of GR852098B publication Critical patent/GR852098B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR852098A 1984-08-31 1985-08-29 GR852098B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843432094 DE3432094A1 (de) 1984-08-31 1984-08-31 Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase

Publications (1)

Publication Number Publication Date
GR852098B true GR852098B (el) 1986-01-02

Family

ID=6244394

Family Applications (1)

Application Number Title Priority Date Filing Date
GR852098A GR852098B (el) 1984-08-31 1985-08-29

Country Status (13)

Country Link
US (1) US4717727A (el)
EP (1) EP0176741B1 (el)
JP (1) JPH0641412B2 (el)
AT (1) ATE38222T1 (el)
AU (1) AU588826B2 (el)
CA (1) CA1246456A (el)
DE (2) DE3432094A1 (el)
DK (1) DK166127C (el)
ES (1) ES8609255A1 (el)
GR (1) GR852098B (el)
IE (1) IE58599B1 (el)
PT (1) PT81058B (el)
ZA (1) ZA856646B (el)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5512586A (en) * 1987-02-10 1996-04-30 Hoechst Aktiengesellschaft Medicaments based on pyridine-2,4- and 2,5-dicarboxylic acid amides
DE3703959A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
DE3703962A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
US5238948A (en) * 1987-02-10 1993-08-24 Hoechst Aktiengesellschaft Pyridine-2,4- and -2,5-dicarboxylic acid derivatives and medicaments based on these compounds
DE3703963A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
GB8702890D0 (en) * 1987-02-10 1987-03-18 Zyma Sa Heterocyclic compounds
DE3707429A1 (de) * 1987-03-07 1988-09-15 Hoechst Ag Substituierte pyridin-2,4-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen
US5271939A (en) * 1988-10-03 1993-12-21 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US4939135A (en) * 1988-10-03 1990-07-03 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5124392A (en) * 1988-10-03 1992-06-23 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5360611A (en) * 1988-10-03 1994-11-01 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following ultraviolet laser irradiation
DE3924093A1 (de) 1989-07-20 1991-02-07 Hoechst Ag N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
DE3930696A1 (de) * 1989-09-14 1991-03-28 Hoechst Ag Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel
DE3938805A1 (de) * 1989-11-23 1991-05-29 Hoechst Ag Pyridin-2,4- und 2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
ZA91291B (en) * 1990-01-16 1991-09-25 Hoechst Ag Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof
DE4020570A1 (de) 1990-06-28 1992-01-02 Hoechst Ag 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung
DE4030999A1 (de) * 1990-10-01 1992-04-09 Hoechst Ag 4- oder 5-substituierte pyridin-2-carbonsaeuren, verfahren zu deren herstellung sowie deren verwendung als arzneimittel
YU9492A (sh) * 1991-02-05 1995-03-27 Hoechst Ag. 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals
DE4233124A1 (de) * 1992-10-02 1994-04-07 Hoechst Ag Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US5624893A (en) * 1993-10-14 1997-04-29 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
EP0878480A1 (en) * 1997-05-14 1998-11-18 H.W. Prof. Dr. Müller A method for the improvement of neuronal regeneration
EP1268639A1 (en) * 2000-02-11 2003-01-02 Huntsman International Llc Fatty acid and polyolefin wax release agent
US7598278B2 (en) * 2002-04-11 2009-10-06 L'oreal Administration of pyridinedicarboxylic acid compounds for stimulating or inducing the growth of human keratinous fibers and/or arresting their loss
WO2005020977A1 (en) * 2003-08-21 2005-03-10 Wisconsin Alumni Research Foundation Alpha-ketoglutarate potentiators of insulin secretion
FR2987742B1 (fr) 2012-03-09 2014-09-26 Oreal Procede de traitement pour la protection et la reparation des fibres keratiniques mettant en œuvre des polysaccharides oxydes
FR3010309B1 (fr) 2013-09-12 2017-03-10 Oreal Procede de traitement des fibres keratiniques avec un polysaccharide et un compose de sphingosine
FR3010308B1 (fr) * 2013-09-12 2016-11-25 Oreal Procede de traitement des fibres keratiniques avec un compose d'acide pyridine dicarboxylique
FR3010312B1 (fr) * 2013-09-12 2015-09-11 Oreal Procede de traitement des fibres keratiniques avec un polysaccharide et un compose d'acide pyridine dicarboxylique
FR3030248B1 (fr) 2014-12-22 2018-03-23 L'oreal Association derive d'acide pyridine-dicarboxylique/agent anti-oxydant particulier
US10788201B2 (en) * 2018-10-03 2020-09-29 Samuel Harriat Solar powered boiler assembly

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2809146A (en) * 1954-09-21 1957-10-08 Phillips Petroleum Co Method of destroying bacteria employing mercuric-chloride complexes of pyridine
US2852519A (en) * 1954-12-27 1958-09-16 Phillips Petroleum Co Method for producing esters of heterocyclic nitrogen carboxylic acids
FR3795M (fr) * 1964-09-09 1965-12-27 Metabio Soc Médicaments a base d'acide quinoléique.
FR2123141A6 (en) * 1971-01-25 1972-09-08 Aries Robert Organophosphorus pesticidal compsns - stabilized by esters of pyridine dicarboxylic acids
DE3002989A1 (de) * 1980-01-29 1981-07-30 Hoechst Ag, 6000 Frankfurt Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels

Also Published As

Publication number Publication date
AU588826B2 (en) 1989-09-28
ES546527A0 (es) 1986-07-16
US4717727A (en) 1988-01-05
IE58599B1 (en) 1993-10-20
PT81058A (de) 1985-09-01
DK166127C (da) 1993-08-09
ZA856646B (en) 1986-05-28
DK397785D0 (da) 1985-08-30
JPH0641412B2 (ja) 1994-06-01
DE3565832D1 (en) 1988-12-01
JPS6160655A (ja) 1986-03-28
ATE38222T1 (de) 1988-11-15
PT81058B (pt) 1987-11-11
AU4692885A (en) 1986-03-06
DE3432094A1 (de) 1986-03-06
DK397785A (da) 1986-03-01
CA1246456A (en) 1988-12-13
IE852150L (en) 1986-02-28
EP0176741B1 (de) 1988-10-26
DK166127B (da) 1993-03-15
EP0176741A1 (de) 1986-04-09
ES8609255A1 (es) 1986-07-16

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