GR851199B - - Google Patents

Info

Publication number
GR851199B
GR851199B GR851199A GR850101199A GR851199B GR 851199 B GR851199 B GR 851199B GR 851199 A GR851199 A GR 851199A GR 850101199 A GR850101199 A GR 850101199A GR 851199 B GR851199 B GR 851199B
Authority
GR
Greece
Application number
GR851199A
Inventor
Nellikunja J Prakash
Sai P Sunkara
David M Stemerick
Michael L Edwards
Original Assignee
Merrell Dow Pharmaceyticals In
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceyticals In filed Critical Merrell Dow Pharmaceyticals In
Publication of GR851199B publication Critical patent/GR851199B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR851199A 1984-05-17 1985-05-16 GR851199B (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61122584A 1984-05-17 1984-05-17
US71848385A 1985-04-04 1985-04-04

Publications (1)

Publication Number Publication Date
GR851199B true GR851199B (el) 1985-11-25

Family

ID=27086467

Family Applications (1)

Application Number Title Priority Date Filing Date
GR851199A GR851199B (el) 1984-05-17 1985-05-16

Country Status (7)

Country Link
EP (1) EP0162413A2 (el)
AU (1) AU567613B2 (el)
DK (1) DK217585A (el)
GR (1) GR851199B (el)
HU (1) HUT40564A (el)
NZ (1) NZ212053A (el)
PH (1) PH22351A (el)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342945A (en) * 1986-12-02 1994-08-30 University Of Florida Research Foundation, Inc. Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
US5091576A (en) * 1986-12-02 1992-02-25 University Of Florida Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives
NZ223340A (en) * 1987-02-03 1991-03-26 Merrell Dow Pharma Polyamine derivatives and pharmaceutical compositions
US5753714A (en) * 1987-02-03 1998-05-19 Merrell Pharmaceuticals Inc. Polyamine derivatives
ZA887410B (en) * 1987-10-08 1989-06-28 Merrell Dow Pharma Polyamine derivatives as antineoplastic agents
US5719193A (en) * 1989-05-23 1998-02-17 Merrell Pharmaceuticals, Inc. Method of potentiating cell-mediated immunity utilizing polyamine derivatives
ZA903804B (en) * 1989-05-23 1991-03-27 Merrell Dow Pharma A method of potentiating cell-mediated immunity utilizing polyamine derivatives
US5561136A (en) * 1990-12-13 1996-10-01 Merrell Pharmaceuticals Inc. Method of treating cancer by conjunctive therapy with N,N'-bis[ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent
FR2706254B1 (fr) * 1993-06-17 1995-08-25 Univ Rennes Composition à usage alimentaire et/ou pharmaceutique pauvre en polyamines.
FR2706255B1 (fr) * 1993-06-17 1995-10-27 Univ Rennes Composition à usage alimentaire et/ou pharmaceutique pauvre en polyamines et applications thérapeutiques.
US5516807A (en) * 1994-10-25 1996-05-14 Warner-Lambert Company Method for treating vascular proliferative disorders following balloon angioplasty
US6166079A (en) * 1996-09-25 2000-12-26 Board Of Regents, The University Of Texas System DFMO for the treatment or prevention of cervical intraepithelial neoplasia
US6235794B1 (en) * 1997-04-03 2001-05-22 University Of Florida Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment
US7087648B1 (en) 1997-10-27 2006-08-08 The Regents Of The University Of California Methods for modulating macrophage proliferation using polyamine analogs
US8198334B2 (en) 1997-10-27 2012-06-12 Pathologica Llc Methods for modulating macrophage proliferation in ocular disease using polyamine analogs
HUP0400494A3 (en) 2000-03-24 2004-08-30 Mediquest Therapeutics Inc Sea Polyamine analogues as cytotoxic agents and pharmaceutical compositions containing them
MXPA03011538A (es) * 2001-06-14 2004-03-09 Otsuka Pharma Co Ltd Composicion medicinal que sustancialmente no causaria dano a la mucosa intestinal.
WO2003013245A1 (en) 2001-08-07 2003-02-20 Wisconsin Alumni Research Foundation Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
WO2012151554A1 (en) * 2011-05-04 2012-11-08 President And Fellows Of Harvard College Polyamines for treating biofilms
CN104072624B (zh) * 2014-05-15 2016-05-18 温州医科大学 一种多胺改性高分子药物及其制备方法与作为抗肿瘤药物的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1705783A (en) * 1982-06-16 1984-01-16 Intreprinderea De Medicamente "Biofarm" Medicine for the treatment of the neoplazic disease

Also Published As

Publication number Publication date
AU567613B2 (en) 1987-11-26
HUT40564A (en) 1987-01-28
PH22351A (en) 1988-08-12
AU4249885A (en) 1985-11-21
NZ212053A (en) 1988-02-29
EP0162413A2 (en) 1985-11-27
DK217585D0 (da) 1985-05-15
DK217585A (da) 1985-11-18

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