GR78364B - - Google Patents

Info

Publication number
GR78364B
GR78364B GR67785A GR820167785A GR78364B GR 78364 B GR78364 B GR 78364B GR 67785 A GR67785 A GR 67785A GR 820167785 A GR820167785 A GR 820167785A GR 78364 B GR78364 B GR 78364B
Authority
GR
Greece
Application number
GR67785A
Other languages
Greek (el)
Inventor
M H Peters
C D Jones
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/331,046 external-priority patent/US4380635A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR78364B publication Critical patent/GR78364B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR67785A 1981-04-03 1982-04-02 GR78364B (US07902200-20110308-C00004.png)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24633381A 1981-04-03 1981-04-03
US24633581A 1981-04-03 1981-04-03
US33104581A 1981-12-16 1981-12-16
US06/331,046 US4380635A (en) 1981-04-03 1981-12-16 Synthesis of acylated benzothiophenes

Publications (1)

Publication Number Publication Date
GR78364B true GR78364B (US07902200-20110308-C00004.png) 1984-09-26

Family

ID=27500218

Family Applications (1)

Application Number Title Priority Date Filing Date
GR67785A GR78364B (US07902200-20110308-C00004.png) 1981-04-03 1982-04-02

Country Status (13)

Country Link
EP (1) EP0062505B1 (US07902200-20110308-C00004.png)
BG (1) BG37378A3 (US07902200-20110308-C00004.png)
DE (1) DE3264853D1 (US07902200-20110308-C00004.png)
DK (1) DK151382A (US07902200-20110308-C00004.png)
ES (1) ES511123A0 (US07902200-20110308-C00004.png)
FI (1) FI821161L (US07902200-20110308-C00004.png)
GB (1) GB2096608B (US07902200-20110308-C00004.png)
GR (1) GR78364B (US07902200-20110308-C00004.png)
HU (1) HU191084B (US07902200-20110308-C00004.png)
IL (1) IL65379A0 (US07902200-20110308-C00004.png)
PL (1) PL130584B1 (US07902200-20110308-C00004.png)
PT (1) PT74693B (US07902200-20110308-C00004.png)
RO (1) RO84584B (US07902200-20110308-C00004.png)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4117512A1 (de) * 1991-05-25 1992-11-26 Schering Ag 2-phenylbenzo(b)furane und -thiophene, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
USRE39049E1 (en) 1992-07-28 2006-03-28 Eli Lilly And Company Methods for inhibiting bone loss
TW366342B (en) 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
USRE38968E1 (en) 1992-07-28 2006-02-07 Eli Lilly And Company Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl-4-[2-(piperidin-1-yl) ethoxyphenylimethanone hydrochloride
US5462949A (en) * 1993-12-21 1995-10-31 Eli Lilly And Company Methods of inhibiting fertility in women
US5478847A (en) 1994-03-02 1995-12-26 Eli Lilly And Company Methods of use for inhibiting bone loss and lowering serum cholesterol
CA2145614A1 (en) * 1994-03-31 1995-10-01 Jeffrey A. Dodge Intermediates and processes for preparing benzothiophene compounds
US5523416A (en) * 1994-07-22 1996-06-04 Eli Lilly And Company Process for preparing 3-(4-aminoethoxy-benzoyl) benzo (B)-thiophenes
US5731436A (en) * 1994-08-31 1998-03-24 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
US5631369A (en) * 1994-08-31 1997-05-20 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceutical agents
CO4410191A1 (es) 1994-09-19 1997-01-09 Lilly Co Eli SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS
US5629425A (en) * 1994-09-19 1997-05-13 Eli Lilly And Company Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene
IL117276A (en) * 1995-02-28 2001-10-31 Lilly Co Eli Benziophene compounds, their preparation and their related compositions
US6395755B1 (en) * 1995-03-10 2002-05-28 Eli Lilly And Company Benzothiophene pharmaceutical compounds
WO1996032937A1 (en) * 1995-04-21 1996-10-24 Eli Lilly And Company Benzothiophenes with novel basic side chains
CN1068883C (zh) * 1995-06-07 2001-07-25 伊莱利利公司 乙烯次磺酸衍生物的合成方法
US5606076A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes
CA2249406A1 (en) * 1996-03-19 1997-09-25 Eli Lilly And Company Synthesis of 3-¬4-(2-aminoethoxy)-benzoyl|-2-aryl-6-hydroxy-benzo¬b|thiophenes
AR013321A1 (es) * 1996-09-25 2000-12-27 Lilly Co Eli Procedimiento para preparar 2-(4-alcoxifenil)-6-alcoxi-benzo[b]tiofenos.
US5916916A (en) * 1996-10-10 1999-06-29 Eli Lilly And Company 1-aryloxy-2-arylnaphthyl compounds, intermediates, compositions, and methods
CN1253556A (zh) * 1997-04-30 2000-05-17 伊莱利利公司 制备苯并噻吩的方法
CA2236254A1 (en) * 1997-04-30 1998-10-30 David Warren Hoard Process for preparing benzo¬b|thiophenes
CA2231013A1 (en) * 1997-04-30 1998-10-30 Eli Lilly And Company Process for preparing benzoic acid derivative intermediates and benzothiophene pharmaceuticals
JP2001524114A (ja) * 1997-04-30 2001-11-27 イーライ・リリー・アンド・カンパニー ベンゾ[b]チオフェン類の製造における中間体および方法
CN1254280A (zh) * 1997-04-30 2000-05-24 伊莱利利公司 用于制备取代的苯并[b]噻吩的区域选择性烷基化方法
AU7261498A (en) * 1997-04-30 1998-11-24 Eli Lilly And Company Intermediates and processes for preparing benzo{b}thiophenes
WO2004029046A2 (en) 2002-09-30 2004-04-08 A/S Gea Farmaceutisk Fabrik Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these
IT1403083B1 (it) * 2010-10-25 2013-10-04 Fidia Farmaceutici Nuova forma polimorfa di raloxifene cloridrato

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947470A (en) * 1974-06-20 1976-03-30 Smithkline Corporation Substituted benzofurans and benzothiophenes
US4001426A (en) * 1974-10-17 1977-01-04 Smithkline Corporation Substituted benzofurans and benzothiophenes
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents

Also Published As

Publication number Publication date
BG37378A3 (en) 1985-05-15
DE3264853D1 (en) 1985-08-29
RO84584A (ro) 1984-07-17
FI821161A0 (fi) 1982-04-02
ES8304116A1 (es) 1983-02-16
EP0062505A1 (en) 1982-10-13
PL130584B1 (en) 1984-08-31
IL65379A0 (en) 1982-05-31
GB2096608A (en) 1982-10-20
DK151382A (da) 1982-10-04
FI821161L (fi) 1982-10-04
GB2096608B (en) 1985-06-12
ES511123A0 (es) 1983-02-16
EP0062505B1 (en) 1985-07-24
PT74693B (en) 1985-01-08
HU191084B (en) 1987-01-28
PL235751A1 (US07902200-20110308-C00004.png) 1982-11-22
RO84584B (ro) 1984-09-30
PT74693A (en) 1982-05-01

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