GR65215B - Method for the preparation of 2-deoxyfortimicin b and intermediates therefor - Google Patents

Method for the preparation of 2-deoxyfortimicin b and intermediates therefor

Info

Publication number
GR65215B
GR65215B GR57744A GR780157744A GR65215B GR 65215 B GR65215 B GR 65215B GR 57744 A GR57744 A GR 57744A GR 780157744 A GR780157744 A GR 780157744A GR 65215 B GR65215 B GR 65215B
Authority
GR
Greece
Prior art keywords
deoxyfortimicin
preparation
intermediates therefor
intermediates
therefor
Prior art date
Application number
GR57744A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of GR65215B publication Critical patent/GR65215B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR57744A 1977-12-21 1978-11-28 Method for the preparation of 2-deoxyfortimicin b and intermediates therefor GR65215B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/863,009 US4169198A (en) 1977-12-21 1977-12-21 2-Deoxyfortimicin B

Publications (1)

Publication Number Publication Date
GR65215B true GR65215B (en) 1980-07-30

Family

ID=25340005

Family Applications (1)

Application Number Title Priority Date Filing Date
GR57744A GR65215B (en) 1977-12-21 1978-11-28 Method for the preparation of 2-deoxyfortimicin b and intermediates therefor

Country Status (10)

Country Link
US (2) US4169198A (el)
JP (1) JPS5498742A (el)
AR (1) AR223468A1 (el)
AU (1) AU522269B2 (el)
BE (1) BE872912A (el)
CA (1) CA1109071A (el)
DE (1) DE2855349A1 (el)
FR (2) FR2412558A1 (el)
GB (1) GB2010838B (el)
GR (1) GR65215B (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4192867A (en) * 1977-12-21 1980-03-11 Abbott Laboratories 2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives
US4312858A (en) * 1978-07-13 1982-01-26 Kowa Company, Ltd. Antibiotic KA-7038 and compositions containing same
US4331804A (en) * 1979-03-29 1982-05-25 Abbott Laboratories 2-Epi-fortimicin A and derivatives
US4263429A (en) * 1979-09-26 1981-04-21 Abbott Laboratories 1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate
US4250304A (en) * 1979-09-26 1981-02-10 Abbott Laboratories 2-Deoxy-2-substituted fortimicin A and B and derivatives
US4275193A (en) * 1979-09-26 1981-06-23 Abbott Laboratories 4,5-Carbamates of fortimicin B
US4230846A (en) * 1979-09-26 1980-10-28 Abbott Laboratories 1,5-Carbamates of fortimicin B and derivatives
US4232147A (en) * 1979-09-26 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B-1,5-carbamates
US4252972A (en) * 1979-09-26 1981-02-24 Abbott Laboratories Fortimicin B-1,2:4,5-bis-carbamates
US4431799A (en) * 1979-09-26 1984-02-14 Abbott Laboratories 6'-Modified fortimicin compounds
US4251516A (en) * 1979-09-26 1981-02-17 Abbott Laboratories 2-Deoxy-3-O-Demethylfortimicins
US4282211A (en) * 1979-09-26 1981-08-04 Abbott Laboratories 1-Epi-2-deoxyfortimicin B and derivatives
US4360666A (en) * 1979-11-06 1982-11-23 Abbott Laboratories 2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives and intermediates therefor
DE3162169D1 (en) * 1980-07-15 1984-03-15 Kowa Co Process for production of antibiotics, and novel antibiotics produced thereby
JPS5740496A (en) * 1980-08-22 1982-03-06 Microbial Chem Res Found Low toxic derivative of istamycin antibiotic
US4418193A (en) * 1982-04-09 1983-11-29 Abbott Laboratories Method of producing 2-epi-fortimicin A
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5145675B2 (el) * 1973-07-23 1976-12-04
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof

Also Published As

Publication number Publication date
BE872912A (fr) 1979-06-20
US4273924A (en) 1981-06-16
AU4119478A (en) 1980-05-08
FR2412558A1 (fr) 1979-07-20
US4169198A (en) 1979-09-25
GB2010838A (en) 1979-07-04
GB2010838B (en) 1983-01-06
DE2855349A1 (de) 1979-07-05
JPS5498742A (en) 1979-08-03
AR223468A1 (es) 1981-08-31
AU522269B2 (en) 1982-05-27
CA1109071A (en) 1981-09-15
FR2431507A1 (fr) 1980-02-15

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