BE872912A - 2-desoxyfortimicine b, utile notamment comme antibiotique, et procede et intermediaires pour sa fabrication - Google Patents

2-desoxyfortimicine b, utile notamment comme antibiotique, et procede et intermediaires pour sa fabrication

Info

Publication number
BE872912A
BE872912A BE192438A BE192438A BE872912A BE 872912 A BE872912 A BE 872912A BE 192438 A BE192438 A BE 192438A BE 192438 A BE192438 A BE 192438A BE 872912 A BE872912 A BE 872912A
Authority
BE
Belgium
Prior art keywords
desoxyfortimicin
intermediaries
antibiotic
useful
manufacturing
Prior art date
Application number
BE192438A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of BE872912A publication Critical patent/BE872912A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BE192438A 1977-12-21 1978-12-20 2-desoxyfortimicine b, utile notamment comme antibiotique, et procede et intermediaires pour sa fabrication BE872912A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/863,009 US4169198A (en) 1977-12-21 1977-12-21 2-Deoxyfortimicin B

Publications (1)

Publication Number Publication Date
BE872912A true BE872912A (fr) 1979-06-20

Family

ID=25340005

Family Applications (1)

Application Number Title Priority Date Filing Date
BE192438A BE872912A (fr) 1977-12-21 1978-12-20 2-desoxyfortimicine b, utile notamment comme antibiotique, et procede et intermediaires pour sa fabrication

Country Status (10)

Country Link
US (2) US4169198A (fr)
JP (1) JPS5498742A (fr)
AR (1) AR223468A1 (fr)
AU (1) AU522269B2 (fr)
BE (1) BE872912A (fr)
CA (1) CA1109071A (fr)
DE (1) DE2855349A1 (fr)
FR (2) FR2412558A1 (fr)
GB (1) GB2010838B (fr)
GR (1) GR65215B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4192867A (en) * 1977-12-21 1980-03-11 Abbott Laboratories 2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives
US4312858A (en) * 1978-07-13 1982-01-26 Kowa Company, Ltd. Antibiotic KA-7038 and compositions containing same
US4331804A (en) * 1979-03-29 1982-05-25 Abbott Laboratories 2-Epi-fortimicin A and derivatives
US4230846A (en) * 1979-09-26 1980-10-28 Abbott Laboratories 1,5-Carbamates of fortimicin B and derivatives
US4232147A (en) * 1979-09-26 1980-11-04 Abbott Laboratories 4-N-Acylfortimicin B-1,5-carbamates
US4282211A (en) * 1979-09-26 1981-08-04 Abbott Laboratories 1-Epi-2-deoxyfortimicin B and derivatives
US4252972A (en) * 1979-09-26 1981-02-24 Abbott Laboratories Fortimicin B-1,2:4,5-bis-carbamates
US4275193A (en) * 1979-09-26 1981-06-23 Abbott Laboratories 4,5-Carbamates of fortimicin B
US4250304A (en) * 1979-09-26 1981-02-10 Abbott Laboratories 2-Deoxy-2-substituted fortimicin A and B and derivatives
US4263429A (en) * 1979-09-26 1981-04-21 Abbott Laboratories 1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate
US4431799A (en) * 1979-09-26 1984-02-14 Abbott Laboratories 6'-Modified fortimicin compounds
US4251516A (en) * 1979-09-26 1981-02-17 Abbott Laboratories 2-Deoxy-3-O-Demethylfortimicins
US4360666A (en) * 1979-11-06 1982-11-23 Abbott Laboratories 2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives and intermediates therefor
EP0044477B1 (fr) * 1980-07-15 1984-02-08 Kowa Company, Ltd. Procédé de préparation d'antibiotiques et antibiotiques ainsi obtenus
JPS5740496A (en) * 1980-08-22 1982-03-06 Microbial Chem Res Found Low toxic derivative of istamycin antibiotic
US4418193A (en) * 1982-04-09 1983-11-29 Abbott Laboratories Method of producing 2-epi-fortimicin A
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931400A (en) * 1973-04-17 1976-01-06 Abbott Laboratories Fortimicin B and process for production thereof
JPS5145675B2 (fr) * 1973-07-23 1976-12-04

Also Published As

Publication number Publication date
GB2010838A (en) 1979-07-04
GB2010838B (en) 1983-01-06
AU4119478A (en) 1980-05-08
US4273924A (en) 1981-06-16
CA1109071A (fr) 1981-09-15
FR2412558A1 (fr) 1979-07-20
DE2855349A1 (de) 1979-07-05
JPS5498742A (en) 1979-08-03
FR2431507A1 (fr) 1980-02-15
AR223468A1 (es) 1981-08-31
AU522269B2 (en) 1982-05-27
GR65215B (en) 1980-07-30
US4169198A (en) 1979-09-25

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