GR37262B - Μεθοδος δια την παρασκευην νεων βιολογικως ενεργων παραγωγων της πιπεραζινης. - Google Patents
Μεθοδος δια την παρασκευην νεων βιολογικως ενεργων παραγωγων της πιπεραζινης.Info
- Publication number
- GR37262B GR37262B GR670137262A GR670137262A GR37262B GR 37262 B GR37262 B GR 37262B GR 670137262 A GR670137262 A GR 670137262A GR 670137262 A GR670137262 A GR 670137262A GR 37262 B GR37262 B GR 37262B
- Authority
- GR
- Greece
- Prior art keywords
- piperazine
- preparation
- biologically active
- group
- new biologically
- Prior art date
Links
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- -1 hydroxy- Chemical class 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- IYABWNGZIDDRAK-UHFFFAOYSA-N allene Chemical group C=C=C IYABWNGZIDDRAK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 150000004885 piperazines Chemical class 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL6603256A NL6603256A (https=) | 1966-03-12 | 1966-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR37262B true GR37262B (el) | 1969-05-10 |
Family
ID=19795968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR670137262A GR37262B (el) | 1966-03-12 | 1967-03-11 | Μεθοδος δια την παρασκευην νεων βιολογικως ενεργων παραγωγων της πιπεραζινης. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3534041A (https=) |
| BE (1) | BE695304A (https=) |
| BR (1) | BR6787719D0 (https=) |
| CH (1) | CH501647A (https=) |
| DE (2) | DE1695556C3 (https=) |
| DK (1) | DK124824B (https=) |
| ES (1) | ES337526A1 (https=) |
| FI (1) | FI51694C (https=) |
| FR (1) | FR6764M (https=) |
| GB (1) | GB1173783A (https=) |
| GR (1) | GR37262B (https=) |
| NL (2) | NL6603256A (https=) |
| SE (1) | SE331999B (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3714148A (en) * | 1968-10-15 | 1973-01-30 | Sumitomo Chemical Co | Process for preparing dibenzazocine derivatives and salts thereof |
| US4217452A (en) * | 1974-02-09 | 1980-08-12 | Akzona Incorporated | Synthesis for the preparation of tetracyclic compounds |
| NL179906C (nl) * | 1974-02-09 | 1986-12-01 | Akzo Nv | Werkwijze voor het bereiden van 1,2,3,4,10,14b-hexahydrodibenzo(c,f)pyrazino (1,2-a)azepine derivaten. |
| NL189199C (nl) * | 1975-04-05 | 1993-02-01 | Akzo Nv | Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten. |
| US4128641A (en) * | 1975-07-31 | 1978-12-05 | Hzi Research Center Inc. | Tetracyclic psychotropic drug |
| NL7610942A (nl) * | 1976-10-02 | 1978-04-04 | Akzo Nv | Werkwijze voor het bereiden van 1,4-diazepine derivaten. |
| NL7809726A (nl) * | 1978-09-26 | 1980-03-28 | Akzo Nv | Nieuwe tetracyclische verbindingen. |
| EP0055546B1 (en) * | 1980-12-31 | 1984-08-01 | Beecham Group Plc | Pentacyclic compounds, processes for their preparation and their use |
| EP0088575B1 (en) * | 1982-03-05 | 1986-12-30 | Beecham Group Plc | Pentacyclic compounds |
| EP0090552A3 (en) * | 1982-03-27 | 1984-04-25 | Beecham Group Plc | Pentacyclic compounds |
| EP0126343A1 (en) * | 1983-05-18 | 1984-11-28 | Beecham Group Plc | Treatment of diarrhoea |
| EP0134984B1 (en) * | 1983-07-16 | 1988-07-13 | Beecham Group Plc | Benzazepine and benzoxazepine derivatives |
| WO1988007997A1 (en) * | 1987-04-10 | 1988-10-20 | Monash University | 1,2,3,4,10,14b-HEXAHYDRODIBENZO[c,f]PYRAZINO-[1,2-a]AZEPINO DERIVATIVES AND 10-AZA, 10-OXA AND 10-THIA ANALOGUES |
| US5189161A (en) * | 1989-08-07 | 1993-02-23 | Hoechst Roussel Pharmaceuticals Inc. | Benzo(b)pyrrolobenzodiazepines |
| US5015738A (en) * | 1989-08-07 | 1991-05-14 | Hoechst-Roussel Pharmaceuticals Inc. | Benzo(b)pyrrolobenzodiazepines |
| EP0475482B1 (en) | 1990-09-13 | 1994-10-05 | Akzo Nobel N.V. | Stabilized solid chemical compositions |
| US5859012A (en) * | 1996-04-03 | 1999-01-12 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| WO1999016769A1 (en) * | 1997-09-26 | 1999-04-08 | Monash University | Resolution of optically-active compounds |
| US6548522B1 (en) | 1999-10-12 | 2003-04-15 | Hoffmann-La Roche Inc. | Method for treating conditions related to the glutamate receptor using carboxylic acid amide derivatives |
| US7355042B2 (en) * | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
| US6723445B2 (en) | 2001-12-31 | 2004-04-20 | Canon Kabushiki Kaisha | Organic light-emitting devices |
| AU2004271800A1 (en) | 2003-09-12 | 2005-03-24 | Pfizer Inc. | Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors |
| CN102633730A (zh) | 2004-12-03 | 2012-08-15 | 先灵公司 | 作为cb1拮抗剂的取代哌嗪 |
| EP2317316A3 (en) | 2005-07-08 | 2011-06-15 | Braincells, Inc. | Methods for identifying agent and conditions that modulate neurogenesis |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| JP2009514969A (ja) | 2005-11-09 | 2009-04-09 | コンビナトアールエックス インコーポレーティッド | 医学的状態を治療するための方法、組成物、およびキット |
| JP2009528266A (ja) | 2006-01-18 | 2009-08-06 | シェーリング コーポレイション | カンナビノイド受容体修飾因子 |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| JP2009536667A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | ５ｈｔ受容体介在性の神経新生 |
| US7858611B2 (en) * | 2006-05-09 | 2010-12-28 | Braincells Inc. | Neurogenesis by modulating angiotensin |
| EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2008083204A2 (en) * | 2006-12-28 | 2008-07-10 | Braincells, Inc. | Modulation of neurogenesis by melatoninergic ligands |
| AU2008204800A1 (en) * | 2007-01-11 | 2008-07-17 | Braincells, Inc. | Modulation of neurogenesis with use of modafinil |
| CA2692268A1 (en) | 2007-06-28 | 2009-01-08 | Intervet International B.V. | Substituted piperazines as cb1 antagonists |
| EP2288345B1 (en) | 2008-04-18 | 2015-06-10 | University College Dublin National University Of Ireland, Dublin | Psycho-pharmaceuticals |
| US9623000B2 (en) | 2008-07-31 | 2017-04-18 | Dekel Pharmaceuticals Ltd | Compositions and methods for treating inflammatory disorders |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3004975A (en) * | 1961-10-17 | Cochs | ||
| US3005789A (en) * | 1955-10-11 | 1961-10-24 | Gen Aniline & Film Corp | Drier composition |
| US3151116A (en) * | 1961-11-03 | 1964-09-29 | Ciba Geigy Corp | Certain 2-aza-indolo [2, 3-alpha] quinolizine compounds |
| US3328396A (en) * | 1961-11-09 | 1967-06-27 | Sterling Drug Inc | 3, 8-di-substituted-3, 8-diazabicyclo [3.2.1] octanes |
| US3196154A (en) * | 1962-05-17 | 1965-07-20 | Sterling Drug Inc | 3-substituted-9-methyl-3, 9-diazabicyclo [3.3.1] nonanes |
| US3317524A (en) * | 1965-02-04 | 1967-05-02 | American Home Prod | Substituted 1, 2, 3, 4-tetrahydro-pyrazino[1, 2-a]indoles |
| US3388128A (en) * | 1965-09-03 | 1968-06-11 | Allan R. Day | Substituted 1, 4-diazabicyclo [4. 4. 9] decanes |
-
0
- NL NL129434D patent/NL129434C/xx active
-
1966
- 1966-03-12 NL NL6603256A patent/NL6603256A/xx unknown
-
1967
- 1967-03-01 US US619867A patent/US3534041A/en not_active Expired - Lifetime
- 1967-03-03 ES ES337526A patent/ES337526A1/es not_active Expired
- 1967-03-09 GB GB01168/67A patent/GB1173783A/en not_active Expired
- 1967-03-09 DE DE1695556A patent/DE1695556C3/de not_active Expired
- 1967-03-09 DE DE1795836A patent/DE1795836C2/de not_active Expired
- 1967-03-10 BE BE695304D patent/BE695304A/xx not_active IP Right Cessation
- 1967-03-10 FI FI670729A patent/FI51694C/fi active
- 1967-03-10 CH CH353167A patent/CH501647A/de not_active IP Right Cessation
- 1967-03-10 BR BR187719/67A patent/BR6787719D0/pt unknown
- 1967-03-10 DK DK128567AA patent/DK124824B/da not_active IP Right Cessation
- 1967-03-11 GR GR670137262A patent/GR37262B/el unknown
- 1967-03-13 FR FR98531A patent/FR6764M/fr not_active Expired
- 1967-03-13 SE SE03430/67A patent/SE331999B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH501647A (de) | 1971-01-15 |
| ES337526A1 (es) | 1968-03-01 |
| NL6603256A (https=) | 1967-09-13 |
| DE1695556A1 (de) | 1972-01-20 |
| NL129434C (https=) | |
| BR6787719D0 (pt) | 1973-12-26 |
| DE1695556B2 (de) | 1980-10-30 |
| DE1695556C3 (de) | 1981-06-25 |
| FI51694B (https=) | 1976-11-30 |
| FR6764M (https=) | 1969-03-10 |
| FI51694C (fi) | 1977-03-10 |
| DK124824B (da) | 1972-11-27 |
| BE695304A (https=) | 1967-09-11 |
| GB1173783A (en) | 1969-12-10 |
| US3534041A (en) | 1970-10-13 |
| SE331999B (https=) | 1971-01-25 |
| DE1795836B1 (de) | 1977-11-24 |
| DE1795836C2 (de) | 1978-07-20 |
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