GR3024008T3 - Dopamine receptor ligands and imaging agents - Google Patents

Dopamine receptor ligands and imaging agents

Info

Publication number
GR3024008T3
GR3024008T3 GR970401663T GR970401663T GR3024008T3 GR 3024008 T3 GR3024008 T3 GR 3024008T3 GR 970401663 T GR970401663 T GR 970401663T GR 970401663 T GR970401663 T GR 970401663T GR 3024008 T3 GR3024008 T3 GR 3024008T3
Authority
GR
Greece
Prior art keywords
imaging agents
receptor ligands
dopamine receptor
receptors
ofuran
Prior art date
Application number
GR970401663T
Other languages
English (en)
Inventor
Hank F Kung
Raymond Murphy
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of GR3024008T3 publication Critical patent/GR3024008T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
GR970401663T 1989-04-17 1997-07-08 Dopamine receptor ligands and imaging agents GR3024008T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/339,006 US5122361A (en) 1989-04-17 1989-04-17 Dopamine receptor ligands and imaging agents

Publications (1)

Publication Number Publication Date
GR3024008T3 true GR3024008T3 (en) 1997-10-31

Family

ID=23327058

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970401663T GR3024008T3 (en) 1989-04-17 1997-07-08 Dopamine receptor ligands and imaging agents

Country Status (11)

Country Link
US (3) US5122361A (el)
EP (1) EP0393838B1 (el)
JP (1) JPH0662560B2 (el)
KR (1) KR930002491B1 (el)
AT (1) ATE154802T1 (el)
CA (1) CA2011745C (el)
DE (1) DE69030963T2 (el)
DK (1) DK0393838T3 (el)
ES (1) ES2103724T3 (el)
GR (1) GR3024008T3 (el)
HK (1) HK1007745A1 (el)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03128558U (el) * 1990-04-06 1991-12-25
US7189737B2 (en) * 1991-08-09 2007-03-13 Research Triangle Institute Cocaine receptor binding ligands
US6531483B1 (en) * 1990-08-09 2003-03-11 Research Triangle Institute Cocaine receptor binding ligands
FR2682953B1 (fr) * 1991-10-23 1995-04-21 Inst Nat Sante Rech Med Nouveaux derives de naphtamides, leur procede de preparation et leur application dans le domaine therapeutique.
CA2129112A1 (en) * 1992-02-06 1993-08-19 Francis David King Benzopyran, benzothiopyran and benzofuran derivatives as 5-ht4 antagonists
US5446147A (en) * 1992-04-03 1995-08-29 Trustees Of The University Of Pennsylvania Fluorinated and iodinated dopamine agents
CA2139503A1 (en) * 1993-05-06 1994-11-24 Christy S. John Compounds for cancer imaging and therapy
US5911970A (en) * 1993-05-06 1999-06-15 Research Corporation Technologies, Inc. Methods for cancer imaging and therapy using benzamine compounds
US5993777A (en) * 1993-05-06 1999-11-30 Research Corporation Technologies, Inc. Benzamide compounds for cancer imaging and therapy
US6517811B2 (en) 1993-05-06 2003-02-11 Research Corporation Technologies, Inc. Compounds for cancer imaging and therapy
GB9320855D0 (en) * 1993-10-09 1993-12-01 Smithkline Beecham Plc Compounds
US5948933A (en) 1997-07-11 1999-09-07 Organix, Inc. Tropane analogs and methods for inhibition of monoamine transport
US7105678B2 (en) 1995-11-03 2006-09-12 Organix, Inc. Boat tropanes
US6171576B1 (en) * 1995-11-03 2001-01-09 Organix Inc. Dopamine transporter imaging agent
US5919934A (en) * 1997-02-19 1999-07-06 The George Washington University Compounds, compositions, and methods for cancer imaging and therapy
CA2329929A1 (en) 1998-04-24 1999-11-04 3-Dimensional Pharmaceuticals, Inc. Amino acid amidinohydrazones, alkoxyguanidines and aminoguanidines as protease inhibitors
DE69942159D1 (de) 1998-06-11 2010-04-29 Ortho Mcneil Pharm Inc Pyrazine Protease Inhibitore
CA2721484A1 (en) * 1999-05-12 2000-11-12 President And Fellows Of Harvard College Dopamine transporter imaging agents
WO2001004117A1 (en) 1999-07-09 2001-01-18 3-Dimensional Pharmaceuticals, Inc. Heteroaryl protease inhibitors and diagnostic imaging agents
WO2002070020A2 (en) * 2001-03-02 2002-09-12 University Of Western Ontario Polymer precursors of radiolabeled compounds, and methods of making and using the same
DE20120708U1 (de) 2001-10-09 2002-08-01 Meltzer Peter C Tropan-Analoga zur Inhibierung des Monoamin-Transports
US20040248850A1 (en) * 2003-02-11 2004-12-09 Kemia, Inc. Compounds for the treatment of HIV infection
JP2006522809A (ja) 2003-04-10 2006-10-05 ３−ディメンショナル ファーマシューティカルズ， インコーポレイテッド 置換フェニルアセトアミおよびプロテアーゼインヒビターとしてのその使用
EP1854781A1 (en) * 2005-02-28 2007-11-14 Taisho Pharmaceutical Co., Ltd Radioactive halogen-labeled phenyloxyaniline derivatives
WO2007109459A2 (en) * 2006-03-21 2007-09-27 Janssen Pharmaceutica, Nv Pyridines and pyridine n-oxides as modulators of thrombin
TW201406770A (zh) * 2012-08-01 2014-02-16 Inst Nuclear Energy Res Atomic Energy Council 造影劑之標幟前驅物及其製備方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3891671A (en) * 1968-08-01 1975-06-24 Ile De France N-(2-pyrrolidyl or piperidyl alkyl)-4-hydroxy benzamides
GB1374366A (en) * 1972-07-21 1974-11-20 Science Union & Cie Propanol derivatives and a process for their preparation
SE8205135D0 (sv) * 1982-09-09 1982-09-09 Astra Laekemedel Ab Benzamido-derivatives
JPS59186969A (ja) * 1983-04-08 1984-10-23 Yoshitomi Pharmaceut Ind Ltd ベンゾフラン−およびベンゾピランカルボキサミド誘導体
CA1297877C (en) * 1983-12-22 1992-03-24 Daniel Lednicer Benzofurancarboxamides useful as antiemetic or antipsychotic agents
US4888353A (en) * 1986-02-28 1989-12-19 Erbamont, Inc. Carboxamides useful as antiemetic or antipsychotic agents
US4656280A (en) * 1984-03-07 1987-04-07 E. I. Du Pont De Nemours And Company Radioiodinated dopamine receptor ligand
SE8503055D0 (sv) * 1985-06-19 1985-06-19 Astra Laekemedel Ab Piperonylcarboxamido derivatives
SE8503054D0 (sv) * 1985-06-19 1985-06-19 Astra Laekemedel Ab Catecholcarboxamides
JPS6248684A (ja) * 1985-08-26 1987-03-03 Sumitomo Chem Co Ltd 新規なヨ−ドブチロフエノン誘導体およびその製造法
FR2593504B1 (fr) * 1986-01-30 1988-12-09 Ile De France Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
EP0320630A1 (en) * 1987-11-19 1989-06-21 The Vanderbilt University Enantiometric iodobenzamides

Also Published As

Publication number Publication date
EP0393838A1 (en) 1990-10-24
KR900016192A (ko) 1990-11-12
JPH0662560B2 (ja) 1994-08-17
US5334728A (en) 1994-08-02
CA2011745C (en) 1997-12-16
KR930002491B1 (ko) 1993-04-02
CA2011745A1 (en) 1990-10-17
DE69030963D1 (de) 1997-07-31
US5426189A (en) 1995-06-20
AU5229290A (en) 1990-10-18
HK1007745A1 (en) 1999-04-23
DK0393838T3 (da) 1997-08-25
AU622301B2 (en) 1992-04-02
ATE154802T1 (de) 1997-07-15
ES2103724T3 (es) 1997-10-01
US5122361A (en) 1992-06-16
JPH02292256A (ja) 1990-12-03
EP0393838B1 (en) 1997-06-25
DE69030963T2 (de) 1997-11-27

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