GR3015659T3 - Process for the preparation of the optical isomers of 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethyl phenyl)-1,6-naphthyridine-3-carboxylic-acid ethyl ester and 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluormethyl phenyl)-1,6-naphthyridine-3 - Google Patents

Process for the preparation of the optical isomers of 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethyl phenyl)-1,6-naphthyridine-3-carboxylic-acid ethyl ester and 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluormethyl phenyl)-1,6-naphthyridine-3

Info

Publication number
GR3015659T3
GR3015659T3 GR950400803T GR950400803T GR3015659T3 GR 3015659 T3 GR3015659 T3 GR 3015659T3 GR 950400803 T GR950400803 T GR 950400803T GR 950400803 T GR950400803 T GR 950400803T GR 3015659 T3 GR3015659 T3 GR 3015659T3
Authority
GR
Greece
Prior art keywords
methyl
naphthyridine
isopropoxy
dihydro
phenyl
Prior art date
Application number
GR950400803T
Other languages
English (en)
Inventor
Wolfgang Dr Herrmann
Juergen Dr Kleinschroth
Klaus Dr Steiner
Original Assignee
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Ag filed Critical Goedecke Ag
Publication of GR3015659T3 publication Critical patent/GR3015659T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR950400803T 1989-03-01 1995-04-03 Process for the preparation of the optical isomers of 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethyl phenyl)-1,6-naphthyridine-3-carboxylic-acid ethyl ester and 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluormethyl phenyl)-1,6-naphthyridine-3 GR3015659T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3906460A DE3906460C1 (el) 1989-03-01 1989-03-01

Publications (1)

Publication Number Publication Date
GR3015659T3 true GR3015659T3 (en) 1995-07-31

Family

ID=6375232

Family Applications (1)

Application Number Title Priority Date Filing Date
GR950400803T GR3015659T3 (en) 1989-03-01 1995-04-03 Process for the preparation of the optical isomers of 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluoromethyl phenyl)-1,6-naphthyridine-3-carboxylic-acid ethyl ester and 1,4-dihydro-5-isopropoxy-2-methyl-4-(2-trifluormethyl phenyl)-1,6-naphthyridine-3

Country Status (8)

Country Link
US (1) US5037987A (el)
EP (1) EP0385423B1 (el)
JP (1) JPH02275879A (el)
AT (1) ATE118205T1 (el)
DE (2) DE3906460C1 (el)
DK (1) DK0385423T3 (el)
ES (1) ES2067577T3 (el)
GR (1) GR3015659T3 (el)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405833D0 (en) * 1994-03-24 1994-05-11 Pfizer Ltd Separation of the enantiomers of amlodipine
EP3560922A1 (de) * 2018-04-24 2019-10-30 Bayer Aktiengesellschaft Verfahren zur herstellung von (4s)- 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-3-carbox-amid durch racemat-spaltung mittels diastereomerer weinsäureester

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3832388A (en) * 1972-09-07 1974-08-27 R Lorenz Resolution of 2-(p-hydroxy)phenylglycine
PL221188A1 (el) * 1979-01-05 1980-12-01 Ciba Geigy Ag
IL75987A (en) * 1984-08-25 1991-07-18 Goedecke Ag Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
DE3602655A1 (de) * 1985-01-29 1987-07-30 Goedecke Ag 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung
US4760081A (en) * 1984-08-25 1988-07-26 Goedecke Aktiengesellschaft 1,6-naphthyridine derivatives useful for treating diseases of the blood vessels
DE3431303A1 (de) * 1984-08-25 1986-02-27 Goedecke Ag 1,6-naphthyridin-derivate, verfahren zu deren herstellung und deren verwendung

Also Published As

Publication number Publication date
ATE118205T1 (de) 1995-02-15
US5037987A (en) 1991-08-06
DE3906460C1 (el) 1990-11-15
ES2067577T3 (es) 1995-04-01
EP0385423B1 (de) 1995-02-08
EP0385423A3 (de) 1991-08-14
DK0385423T3 (da) 1995-06-12
EP0385423A2 (de) 1990-09-05
JPH02275879A (ja) 1990-11-09
DE59008426D1 (de) 1995-03-23

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