GR3003761T3 - - Google Patents
Info
- Publication number
- GR3003761T3 GR3003761T3 GR920400183T GR920400183T GR3003761T3 GR 3003761 T3 GR3003761 T3 GR 3003761T3 GR 920400183 T GR920400183 T GR 920400183T GR 920400183 T GR920400183 T GR 920400183T GR 3003761 T3 GR3003761 T3 GR 3003761T3
- Authority
- GR
- Greece
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06043—Leu-amino acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868630928A GB8630928D0 (en) | 1986-12-24 | 1986-12-24 | Compounds |
| GB878717924A GB8717924D0 (en) | 1987-07-29 | 1987-07-29 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3003761T3 true GR3003761T3 (US20050192411A1-20050901-C00001.png) | 1993-03-16 |
Family
ID=26291743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR920400183T GR3003761T3 (US20050192411A1-20050901-C00001.png) | 1986-12-24 | 1992-02-11 |
Country Status (12)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8729804D0 (en) * | 1987-12-22 | 1988-02-03 | Beecham Group Plc | Novel compounds |
| GB8814813D0 (en) * | 1988-06-22 | 1988-07-27 | Beecham Group Plc | Novel compounds |
| WO1990005141A1 (en) * | 1988-11-10 | 1990-05-17 | Australian Commercial Research & Development Limited | Amino acid and peptide inhibitors of human leukocytic elastase and collagenase |
| GB9000846D0 (en) * | 1990-01-15 | 1990-03-14 | Beecham Group Plc | Novel compounds |
| GB9022117D0 (en) * | 1990-10-11 | 1990-11-21 | Beecham Group Plc | Novel compounds |
| US5187305A (en) * | 1990-11-26 | 1993-02-16 | Glaxo Inc. | S-nitroso-N-alkonoylpenicillamines |
| GB9107367D0 (en) * | 1991-04-08 | 1991-05-22 | Smithkline Beecham Plc | Novel compounds |
| WO1993014112A1 (en) * | 1992-01-15 | 1993-07-22 | Merck & Co., Inc. | Substituted phosphinic acid-containing peptidyl derivatives as antidegenerative agents |
| EP1002556A3 (en) * | 1992-05-01 | 2001-01-10 | British Biotech Pharmaceuticals Limited | Use of MMP inhibitors |
| GB9211707D0 (en) * | 1992-06-03 | 1992-07-15 | Celltech Ltd | Peptidyl derivatives |
| AU5292193A (en) * | 1992-10-02 | 1994-04-26 | Merck & Co., Inc. | N-(mercaptoacyl)peptidyl derivatives as antidegenerative agents |
| US6090785A (en) * | 1992-10-15 | 2000-07-18 | Merck & Co., Inc. | Substituted N-carboxyalkylpeptidyl derivatives as antidegenerative agents |
| CA2149640A1 (en) * | 1992-11-25 | 1994-06-09 | Kevin T. Chapman | Carboxy-peptidyl derivatives as antidegenerative active agents |
| GB9323165D0 (en) * | 1993-11-10 | 1994-01-05 | Chiros Ltd | Compounds |
| US5840698A (en) * | 1994-10-27 | 1998-11-24 | Affymax Technologies N.V. | Inhibitors of collagenase-1 and stormelysin-I metalloproteases, pharmaceutical compositions comprising same and methods of their use |
| US5831004A (en) | 1994-10-27 | 1998-11-03 | Affymax Technologies N.V. | Inhibitors of metalloproteases, pharmaceutical compositions comprising same and methods of their use |
| AR002945A1 (es) * | 1994-11-15 | 1998-05-27 | Bayer Corp | Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos |
| US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
| CA2217857A1 (en) * | 1995-05-10 | 1996-11-14 | Darwin Discovery Limited | Peptide compounds which inhibit metalloproteinase and tnf liberation and their therapeutic uses |
| WO1996035687A1 (en) * | 1995-05-10 | 1996-11-14 | Chiroscience Limited | Peptidyl compounds and their therapeutic use |
| US5932579A (en) * | 1996-06-18 | 1999-08-03 | Affymax Technologies N.V. | Collagenase-1 and stromelysin-1 inhibitors, pharmaceutical compositions comprising same and methods of their use |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH628247A5 (en) * | 1975-01-03 | 1982-02-26 | Ciba Geigy Ag | Aqueous, film-forming concentrates for extinguishing or preventing fire with a content of non-anionic compounds containing perfluoroalkylalkylenethio groups |
| US4263293A (en) * | 1980-05-30 | 1981-04-21 | E. R. Squibb & Sons, Inc. | Heterocyclic containing amides as inhibitors of mammalian collagenase |
| US4410543A (en) * | 1981-03-26 | 1983-10-18 | Ciba-Geigy Corporation | Carboxylated oxime-carbamates and their use in controlling pests |
| DE3467754D1 (de) * | 1983-10-03 | 1988-01-07 | Squibb & Sons Inc | Enkephalinase inhibitors |
| US4595700A (en) * | 1984-12-21 | 1986-06-17 | G. D. Searle & Co. | Thiol based collagenase inhibitors |
-
1987
- 1987-12-22 DE DE8787311321T patent/DE3774858D1/de not_active Expired - Fee Related
- 1987-12-22 NZ NZ223037A patent/NZ223037A/en unknown
- 1987-12-22 EP EP87311321A patent/EP0273689B1/en not_active Expired - Lifetime
- 1987-12-22 ES ES198787311321T patent/ES2038678T3/es not_active Expired - Lifetime
- 1987-12-22 IE IE350587A patent/IE60751B1/en not_active IP Right Cessation
- 1987-12-22 US US07/136,913 patent/US4937243A/en not_active Expired - Fee Related
- 1987-12-22 DK DK681287A patent/DK681287A/da not_active Application Discontinuation
- 1987-12-22 AU AU82926/87A patent/AU599736B2/en not_active Ceased
- 1987-12-22 PT PT86433A patent/PT86433B/pt not_active IP Right Cessation
- 1987-12-22 CA CA000555081A patent/CA1322073C/en not_active Expired - Fee Related
- 1987-12-23 KR KR1019870015022A patent/KR880007451A/ko not_active Application Discontinuation
-
1990
- 1990-04-30 US US07/517,391 patent/US5109000A/en not_active Expired - Fee Related
-
1992
- 1992-02-11 GR GR920400183T patent/GR3003761T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU8292687A (en) | 1988-09-01 |
| ES2038678T3 (es) | 1993-08-01 |
| DE3774858D1 (de) | 1992-01-09 |
| DK681287D0 (da) | 1987-12-22 |
| EP0273689A3 (en) | 1989-07-12 |
| DK681287A (da) | 1988-06-25 |
| KR880007451A (ko) | 1988-08-27 |
| US4937243A (en) | 1990-06-26 |
| PT86433B (pt) | 1990-11-20 |
| US5109000A (en) | 1992-04-28 |
| AU599736B2 (en) | 1990-07-26 |
| IE873505L (en) | 1988-06-24 |
| EP0273689B1 (en) | 1991-11-27 |
| PT86433A (en) | 1988-01-01 |
| IE60751B1 (en) | 1994-08-10 |
| CA1322073C (en) | 1993-09-07 |
| EP0273689A2 (en) | 1988-07-06 |
| NZ223037A (en) | 1991-04-26 |
