GR22816B - METHOD OF PREPARATION OF NEW ANTIPERTENSION COMPOSITIONS. - Google Patents
METHOD OF PREPARATION OF NEW ANTIPERTENSION COMPOSITIONS.Info
- Publication number
- GR22816B GR22816B GR610122816A GR610122816A GR22816B GR 22816 B GR22816 B GR 22816B GR 610122816 A GR610122816 A GR 610122816A GR 610122816 A GR610122816 A GR 610122816A GR 22816 B GR22816 B GR 22816B
- Authority
- GR
- Greece
- Prior art keywords
- collectively
- active ingredients
- antipertension
- compositions
- preparation
- Prior art date
Links
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
έθοδος παρασκευής αντι-υπερτασικής συνθέσεως ήτιςπεριλαμβάνει ανάμιξιν μεθ' ενός φαρμακευτικού εκδόχου ενεργών συστατικών εχόντων συλλογικώς αμφότερα τα επόμενα χαρακτηριστικά : (1) την ιδιότητα εξαντλήσεως in vivo της ποσότητος νοραδρεναλίνης εν τοίς καρδιακοίς ιστοίς, (2) την ιδιότητα αναστολής in vivo της ενζυματικη ενεργείας της των θηλαστικών αποκαρβοξυλάσης επί της διυδροξυφαινυλαλανίνης και 4-υδροξυθρυπτοφάνης, εκάστης των ειρημένων ιδιοτήτων αποτελούσης χαρακτηριστικόν γνώρισμα το ελάχιστον μιάς ενώσεως περιλαμβανομένης είς τα ειρημένα ενεργά συστατικά, των ειρημένων ενεργών συστατικών υπαρχόντων είς ποσότητα το ελάχιστιον 50% της αποτελεσματικής πρός αναστολήν της αποκαρβοξυλάσης δόσεως της ευρεθείσης διά τα ειρημένα ενεργά συστατικά συλλογικώς κατά την μνησθείσαν δοκιμασίαν, των εν λόγω ενεργών συστατικών εχόντων συλλογικώς μίαν κατά 50% αποτελεσματικήν πρός εξάντλησιν κατεχολαμινών δόσιν το ελάχιστιον δέκα φοράς την τοιαύτην πρός αναστολήν της αποκαρβοξυλάσης. A method of preparing an antihypertensive composition comprising mixing with a pharmaceutical excipient active ingredients having collectively both of the following characteristics: (1) of decarboxylase mammals on dihydroxyphenylalanine and 4-hydroxytryptophan, each of the said properties being a feature of at least one compound Said active ingredients collectively in the assayed test, said active ingredients having collectively a 50% effective catecholamine depletion dose at least ten times the same to inhibit decarboxylase.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR610122816A GR22816B (en) | 1961-06-08 | 1961-06-08 | METHOD OF PREPARATION OF NEW ANTIPERTENSION COMPOSITIONS. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GR610122816A GR22816B (en) | 1961-06-08 | 1961-06-08 | METHOD OF PREPARATION OF NEW ANTIPERTENSION COMPOSITIONS. |
Publications (1)
Publication Number | Publication Date |
---|---|
GR22816B true GR22816B (en) | 1962-02-03 |
Family
ID=36863645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR610122816A GR22816B (en) | 1961-06-08 | 1961-06-08 | METHOD OF PREPARATION OF NEW ANTIPERTENSION COMPOSITIONS. |
Country Status (1)
Country | Link |
---|---|
GR (1) | GR22816B (en) |
-
1961
- 1961-06-08 GR GR610122816A patent/GR22816B/en unknown
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