GR1006924B - Edta-type cyclodextrin derivatives for metal ion binding and their complexes with gadolinium (iii) for use in magnetic resonance imaging. - Google Patents

Edta-type cyclodextrin derivatives for metal ion binding and their complexes with gadolinium (iii) for use in magnetic resonance imaging.

Info

Publication number
GR1006924B
GR1006924B GR20090100531A GR20090100531A GR1006924B GR 1006924 B GR1006924 B GR 1006924B GR 20090100531 A GR20090100531 A GR 20090100531A GR 20090100531 A GR20090100531 A GR 20090100531A GR 1006924 B GR1006924 B GR 1006924B
Authority
GR
Greece
Prior art keywords
complexes
gadolinium
magnetic resonance
resonance imaging
edta
Prior art date
Application number
GR20090100531A
Other languages
Greek (el)
Inventor
Κωνσταντινα Γιαννακοπουλου
Ειρηνη Μαυριδου
Μιχαλης Φαρδης
Davide Maffeo
Μαρια Λαμπροπουλου
Original Assignee
Ειρηνη Μαυριδου
Κωνσταντινα Γιαννακοπουλου
Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) "Δημοκριτος",
Μιχαλης Φαρδης
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ειρηνη Μαυριδου, Κωνσταντινα Γιαννακοπουλου, Εθνικο Κεντρο Ερευνας Φυσικων Επιστημων (Εκεφε) "Δημοκριτος",, Μιχαλης Φαρδης filed Critical Ειρηνη Μαυριδου
Priority to GR20090100531A priority Critical patent/GR1006924B/en
Publication of GR1006924B publication Critical patent/GR1006924B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C08B37/0015—Inclusion compounds, i.e. host-guest compounds, e.g. polyrotaxanes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention relates to new products hexakis- and heptakis- and octakis[bis(carboxymethyl)amino]-a- and -β- and -γ-cyclodextrin, their multimetal complexes and specifically the water soluble complexes with Gadolinium(IΙΙ) for use as contrast agents in Magnetic Resonance Imaging, due to remarkably enhanced relaxivity values measured in a magnetic field.
GR20090100531A 2009-09-28 2009-09-28 Edta-type cyclodextrin derivatives for metal ion binding and their complexes with gadolinium (iii) for use in magnetic resonance imaging. GR1006924B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GR20090100531A GR1006924B (en) 2009-09-28 2009-09-28 Edta-type cyclodextrin derivatives for metal ion binding and their complexes with gadolinium (iii) for use in magnetic resonance imaging.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GR20090100531A GR1006924B (en) 2009-09-28 2009-09-28 Edta-type cyclodextrin derivatives for metal ion binding and their complexes with gadolinium (iii) for use in magnetic resonance imaging.

Publications (1)

Publication Number Publication Date
GR1006924B true GR1006924B (en) 2010-07-30

Family

ID=42140044

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20090100531A GR1006924B (en) 2009-09-28 2009-09-28 Edta-type cyclodextrin derivatives for metal ion binding and their complexes with gadolinium (iii) for use in magnetic resonance imaging.

Country Status (1)

Country Link
GR (1) GR1006924B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3714904A1 (en) 2019-03-27 2020-09-30 National Center For Scientific Research "Demokritos" Iminodiacetic acid substituted cyclodextrins as potentiators of beta-lactam antibiotics

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3974274A (en) * 1972-12-23 1976-08-10 Tanabe Seiyaku Co., Ltd. Process for preparing a cyclodextrin derivative
EP0710673A2 (en) * 1990-05-21 1996-05-08 Toppan Printing Co., Ltd. Cyclodextrin derivatives
US6113880A (en) * 1997-12-17 2000-09-05 Schering Aktiengesellschaft Polyrotaxane derivatives for x-ray and nuclear magnetic resonance imaging
FR2804437A1 (en) * 2000-01-31 2001-08-03 Chiralsep Sarl PROCESS FOR THE PREPARATION OF MONO-, DI- AND TRICARBOXY CYCLODEXTRINS BY REGIOSELECTIVE OXIDATION IN POSITION 6 OF ALPHA OR BETA OR NATIVE GAMMA-CYCLODEXTRINS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3974274A (en) * 1972-12-23 1976-08-10 Tanabe Seiyaku Co., Ltd. Process for preparing a cyclodextrin derivative
EP0710673A2 (en) * 1990-05-21 1996-05-08 Toppan Printing Co., Ltd. Cyclodextrin derivatives
US6113880A (en) * 1997-12-17 2000-09-05 Schering Aktiengesellschaft Polyrotaxane derivatives for x-ray and nuclear magnetic resonance imaging
FR2804437A1 (en) * 2000-01-31 2001-08-03 Chiralsep Sarl PROCESS FOR THE PREPARATION OF MONO-, DI- AND TRICARBOXY CYCLODEXTRINS BY REGIOSELECTIVE OXIDATION IN POSITION 6 OF ALPHA OR BETA OR NATIVE GAMMA-CYCLODEXTRINS

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3714904A1 (en) 2019-03-27 2020-09-30 National Center For Scientific Research "Demokritos" Iminodiacetic acid substituted cyclodextrins as potentiators of beta-lactam antibiotics

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PG Patent granted