GB9929783D0 - Toscana virus nucleoprotein - Google Patents
Toscana virus nucleoproteinInfo
- Publication number
- GB9929783D0 GB9929783D0 GBGB9929783.0A GB9929783A GB9929783D0 GB 9929783 D0 GB9929783 D0 GB 9929783D0 GB 9929783 A GB9929783 A GB 9929783A GB 9929783 D0 GB9929783 D0 GB 9929783D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- toscana virus
- toscana
- virus nucleoprotein
- virus
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 101001112212 Toscana virus Nucleoprotein Proteins 0.000 title abstract 2
- 241000713154 Toscana virus Species 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 101710132601 Capsid protein Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000007416 antiviral immune response Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000008348 humoral response Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/12011—Bunyaviridae
- C12N2760/12022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/12011—Bunyaviridae
- C12N2760/12034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Silicates, Zeolites, And Molecular Sieves (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Surprinsingly, it has been discovered that the core protein antigen of Toscana virus can induce a protective humoral response. The invention relates to compositions comprising Toscana virus nucleoprotein. These may be used in the treatment or prophylaxis of Toscana virus infection. Also provided is the use of an internal virus antigen in the manufacture of a medicament for eliciting a neutralising humoral anti-viral immune response.
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9929783.0A GB9929783D0 (en) | 1999-12-16 | 1999-12-16 | Toscana virus nucleoprotein |
DK00987600T DK1237571T3 (en) | 1999-12-16 | 2000-12-18 | Toscana virus nukleinprotein |
PCT/IB2000/002031 WO2001044288A2 (en) | 1999-12-16 | 2000-12-18 | Toscana virus nucleoprotein |
EP00987600A EP1237571B1 (en) | 1999-12-16 | 2000-12-18 | Toscana virus nucleoprotein |
AU23901/01A AU2390101A (en) | 1999-12-16 | 2000-12-18 | Toscana virus nucleoprotein |
ES00987600T ES2293934T3 (en) | 1999-12-16 | 2000-12-18 | TUSCAN VIRUS NUCLEOPROTEIN. |
DE60036563T DE60036563T2 (en) | 1999-12-16 | 2000-12-18 | NUCLEOPROTEIN OF TUSCANAVIRUS |
AT00987600T ATE374040T1 (en) | 1999-12-16 | 2000-12-18 | NUCLEOPROTEIN OF THE TOSCANA VIRUS |
PT00987600T PT1237571E (en) | 1999-12-16 | 2000-12-18 | Toscana virus nucleoprotein |
CY20071101586T CY1107607T1 (en) | 1999-12-16 | 2007-12-14 | TOSCANA NUCLEAR PROTEIN |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9929783.0A GB9929783D0 (en) | 1999-12-16 | 1999-12-16 | Toscana virus nucleoprotein |
Publications (1)
Publication Number | Publication Date |
---|---|
GB9929783D0 true GB9929783D0 (en) | 2000-02-09 |
Family
ID=10866464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GBGB9929783.0A Ceased GB9929783D0 (en) | 1999-12-16 | 1999-12-16 | Toscana virus nucleoprotein |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1237571B1 (en) |
AT (1) | ATE374040T1 (en) |
AU (1) | AU2390101A (en) |
CY (1) | CY1107607T1 (en) |
DE (1) | DE60036563T2 (en) |
DK (1) | DK1237571T3 (en) |
ES (1) | ES2293934T3 (en) |
GB (1) | GB9929783D0 (en) |
PT (1) | PT1237571E (en) |
WO (1) | WO2001044288A2 (en) |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5298423A (en) * | 1987-11-25 | 1994-03-29 | The United States Of America As Represented By The Secretary Of The Army | Nucleotide sequences encoding the expression of a Hantaan virus nucleocapsid protein and G1 and G2 glycoproteins |
ITMI980889A1 (en) * | 1998-04-24 | 1999-10-24 | Diesse Diagnostica | RECOMBINANT NUCLEOPROTEIN OF THE TUSCAN VIRUS |
-
1999
- 1999-12-16 GB GBGB9929783.0A patent/GB9929783D0/en not_active Ceased
-
2000
- 2000-12-18 ES ES00987600T patent/ES2293934T3/en not_active Expired - Lifetime
- 2000-12-18 PT PT00987600T patent/PT1237571E/en unknown
- 2000-12-18 EP EP00987600A patent/EP1237571B1/en not_active Expired - Lifetime
- 2000-12-18 DK DK00987600T patent/DK1237571T3/en active
- 2000-12-18 AU AU23901/01A patent/AU2390101A/en not_active Abandoned
- 2000-12-18 WO PCT/IB2000/002031 patent/WO2001044288A2/en active IP Right Grant
- 2000-12-18 AT AT00987600T patent/ATE374040T1/en active
- 2000-12-18 DE DE60036563T patent/DE60036563T2/en not_active Expired - Lifetime
-
2007
- 2007-12-14 CY CY20071101586T patent/CY1107607T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
ATE374040T1 (en) | 2007-10-15 |
EP1237571A2 (en) | 2002-09-11 |
DE60036563D1 (en) | 2007-11-08 |
ES2293934T3 (en) | 2008-04-01 |
EP1237571B1 (en) | 2007-09-26 |
DK1237571T3 (en) | 2008-01-02 |
PT1237571E (en) | 2007-12-31 |
CY1107607T1 (en) | 2013-03-13 |
AU2390101A (en) | 2001-06-25 |
WO2001044288A3 (en) | 2002-01-24 |
DE60036563T2 (en) | 2008-07-17 |
WO2001044288A2 (en) | 2001-06-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AT | Applications terminated before publication under section 16(1) |