GB991602A - Antibiotics and their purification - Google Patents
Antibiotics and their purificationInfo
- Publication number
- GB991602A GB991602A GB895761A GB895761A GB991602A GB 991602 A GB991602 A GB 991602A GB 895761 A GB895761 A GB 895761A GB 895761 A GB895761 A GB 895761A GB 991602 A GB991602 A GB 991602A
- Authority
- GB
- United Kingdom
- Prior art keywords
- polymyxin
- antibiotics
- purification
- polymyxins
- sulphates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/60—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
- C07K7/62—Polymyxins; Related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A polymyxin is purified by a process which comprises treating an aqueous solution of the polymyxin with a permanganate at a pH not above pH 8.0. Examples describe the treatment of solutions of polymyxin B hydrochloride and of the sulphates of polymyxins A, B and E.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB895761A GB991602A (en) | 1961-03-10 | 1961-03-10 | Antibiotics and their purification |
CH279762A CH399479A (en) | 1961-03-10 | 1962-03-08 | Process for purifying polymyxins |
ES0275328A ES275328A1 (en) | 1961-03-10 | 1962-03-09 | Antibiotics and their purification |
SE263562A SE316570B (en) | 1961-03-10 | 1962-03-09 | |
BR13702462A BR6237024D0 (en) | 1961-03-10 | 1962-03-09 | PROCESS FOR PURIFICATION OF AN ANTIBIOTIC POLYMIXIN |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB895761A GB991602A (en) | 1961-03-10 | 1961-03-10 | Antibiotics and their purification |
Publications (1)
Publication Number | Publication Date |
---|---|
GB991602A true GB991602A (en) | 1965-05-12 |
Family
ID=9862573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB895761A Expired GB991602A (en) | 1961-03-10 | 1961-03-10 | Antibiotics and their purification |
Country Status (5)
Country | Link |
---|---|
BR (1) | BR6237024D0 (en) |
CH (1) | CH399479A (en) |
ES (1) | ES275328A1 (en) |
GB (1) | GB991602A (en) |
SE (1) | SE316570B (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007142611A1 (en) * | 2006-06-02 | 2007-12-13 | Biotika A.S. | Method of polymyxin b recovery from fermentation broth |
WO2010058427A2 (en) | 2008-11-24 | 2010-05-27 | Reliance Life Sciences Pvt. Ltd. | Process for production and purification of polymyxin b sulfate |
US8119371B2 (en) | 2006-06-15 | 2012-02-21 | Biotika A.S. | Process for the preparation of polymyxin B employing (PAENI) Bacillus polymyxa |
RU2492180C2 (en) * | 2011-12-07 | 2013-09-10 | Учреждение Российской академии наук Центр "Биоинженерия" РАН | Method of producing pharmaceutical substance polymyxin b |
CN104327167A (en) * | 2014-09-28 | 2015-02-04 | 河北圣雪大成制药有限责任公司 | Technology for extracting polymyxin B through precipitation method |
-
1961
- 1961-03-10 GB GB895761A patent/GB991602A/en not_active Expired
-
1962
- 1962-03-08 CH CH279762A patent/CH399479A/en unknown
- 1962-03-09 ES ES0275328A patent/ES275328A1/en not_active Expired
- 1962-03-09 SE SE263562A patent/SE316570B/xx unknown
- 1962-03-09 BR BR13702462A patent/BR6237024D0/en unknown
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007142611A1 (en) * | 2006-06-02 | 2007-12-13 | Biotika A.S. | Method of polymyxin b recovery from fermentation broth |
US7951913B2 (en) | 2006-06-02 | 2011-05-31 | Biotika A.S. | Method of polymyxin B recovery from fermentation broth |
US8119371B2 (en) | 2006-06-15 | 2012-02-21 | Biotika A.S. | Process for the preparation of polymyxin B employing (PAENI) Bacillus polymyxa |
WO2010058427A2 (en) | 2008-11-24 | 2010-05-27 | Reliance Life Sciences Pvt. Ltd. | Process for production and purification of polymyxin b sulfate |
RU2492180C2 (en) * | 2011-12-07 | 2013-09-10 | Учреждение Российской академии наук Центр "Биоинженерия" РАН | Method of producing pharmaceutical substance polymyxin b |
CN104327167A (en) * | 2014-09-28 | 2015-02-04 | 河北圣雪大成制药有限责任公司 | Technology for extracting polymyxin B through precipitation method |
Also Published As
Publication number | Publication date |
---|---|
ES275328A1 (en) | 1962-05-16 |
CH399479A (en) | 1965-09-30 |
BR6237024D0 (en) | 1973-05-24 |
SE316570B (en) | 1969-10-27 |
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