GB9914222D0 - Pharmeceutical compounds - Google Patents

Pharmeceutical compounds

Info

Publication number
GB9914222D0
GB9914222D0 GBGB9914222.6A GB9914222A GB9914222D0 GB 9914222 D0 GB9914222 D0 GB 9914222D0 GB 9914222 A GB9914222 A GB 9914222A GB 9914222 D0 GB9914222 D0 GB 9914222D0
Authority
GB
United Kingdom
Prior art keywords
pharmeceutical
compounds
pharmeceutical compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GBGB9914222.6A
Other versions
GB2351081A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Forschung GmbH
Original Assignee
Lilly Forschung GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Forschung GmbH filed Critical Lilly Forschung GmbH
Priority to GB9914222A priority Critical patent/GB2351081A/en
Publication of GB9914222D0 publication Critical patent/GB9914222D0/en
Priority to AU57228/00A priority patent/AU5722800A/en
Priority to PCT/US2000/011881 priority patent/WO2000078726A1/en
Publication of GB2351081A publication Critical patent/GB2351081A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB9914222A 1999-06-18 1999-06-18 Pharmaceutically active imidazoline compounds and analogues thereof Withdrawn GB2351081A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB9914222A GB2351081A (en) 1999-06-18 1999-06-18 Pharmaceutically active imidazoline compounds and analogues thereof
AU57228/00A AU5722800A (en) 1999-06-18 2000-06-19 Imidazoline derivatives for the treatment of diabetes, especially type ii diabetes
PCT/US2000/011881 WO2000078726A1 (en) 1999-06-18 2000-06-19 Imidazoline derivatives for the treatment of diabetes, especially type ii diabetes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9914222A GB2351081A (en) 1999-06-18 1999-06-18 Pharmaceutically active imidazoline compounds and analogues thereof

Publications (2)

Publication Number Publication Date
GB9914222D0 true GB9914222D0 (en) 1999-08-18
GB2351081A GB2351081A (en) 2000-12-20

Family

ID=10855593

Family Applications (1)

Application Number Title Priority Date Filing Date
GB9914222A Withdrawn GB2351081A (en) 1999-06-18 1999-06-18 Pharmaceutically active imidazoline compounds and analogues thereof

Country Status (3)

Country Link
AU (1) AU5722800A (en)
GB (1) GB2351081A (en)
WO (1) WO2000078726A1 (en)

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BRPI0107715B8 (en) 2000-01-21 2021-05-25 Novartis Ag pharmaceutical product comprising an inhibitor of dipeptidyl peptidase-iv and metformin, as well as uses of said pharmaceutical product and inhibitor of dipeptidyl peptidase-iv
EP1395548A1 (en) 2001-02-26 2004-03-10 4Sc Ag Derivatives of diphenylurea, diphenyloxalic acid diamide and diphenylsulfuric acid diamide and their use as medicaments
MY151199A (en) 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
CA2494164A1 (en) 2002-08-23 2004-03-04 Rigel Pharmaceuticals, Inc. Pyridyl substituted heterocycles useful for treating or preventing hcv infection
FR2846328B1 (en) * 2002-10-23 2004-12-10 Servier Lab NEW IMIDAZOLINE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
WO2004063159A1 (en) * 2003-01-10 2004-07-29 Idemitsu Kosan Co., Ltd. Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
WO2004099164A1 (en) 2003-05-02 2004-11-18 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating hcv infection
US7777051B2 (en) * 2003-05-13 2010-08-17 Icagen, Inc. Asymmetric benzimidazoles and related compounds as potassium channel modulators
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
US7037927B2 (en) * 2003-10-16 2006-05-02 Abbott Laboratories Amides that inhibit vanilloid receptor subtype 1 (VR1) receptor
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
SI1731512T1 (en) 2004-03-05 2015-01-30 Nissan Chemical Industries, Ltd. Isoxazoline-substituted benzamide compound and noxious organism control agent
CN100360523C (en) * 2005-04-28 2008-01-09 江苏吴中苏药医药开发有限责任公司 1,2,4 furodazole-phenoxyalkyl substituted derivative of iso-oxazole, preparation method and anti virus application
WO2007027230A2 (en) 2005-05-02 2007-03-08 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
ES2396913T3 (en) * 2005-08-04 2013-03-01 Sirtris Pharmaceuticals, Inc. Sirtuin modulating compounds
CN102908351B (en) 2005-09-14 2014-07-23 武田药品工业株式会社 Dipeptidyl peptidase inhibitors for treating diabetes
TW200803740A (en) * 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (en) 2005-12-30 2013-10-21 Du Pont Isoxazolines for controlling invertebrate pests
PT2001892E (en) 2006-03-17 2013-07-04 Ambit Biosciences Corp Imidazolothiazole compounds for the treatment of proliferative diseases
RU2008143179A (en) * 2006-03-31 2010-05-10 Новартис АГ (CH) ORGANIC COMPOUNDS
US8623875B2 (en) 2007-06-13 2014-01-07 E.I. Du Pont De Nemours And Company Isoxazoline insecticides
TW200916472A (en) 2007-06-20 2009-04-16 Sirtris Pharmaceuticals Inc Sirtuin modulating compounds
TWI430995B (en) 2007-06-26 2014-03-21 Du Pont Naphthalene isoxazoline invertebrate pest control agents
BRPI0810929B8 (en) 2007-06-27 2022-12-06 Du Pont use of a compound of formula 1
TWI461411B (en) 2007-08-17 2014-11-21 Du Pont Method for preparing 5-haloalkyl-4,5-dihydroisoxazole derivatives
WO2009038757A2 (en) 2007-09-19 2009-03-26 Ambit Biosciences Corporation Solid forms comprising n-(5-tert-butyl-isoxazol-3-yl)-n'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith
US8367584B2 (en) 2007-10-03 2013-02-05 E.I. Du Pont De Nemours And Company Naphthalene isoxazoline compounds for control of invertebrate pests
WO2009145829A1 (en) * 2008-04-01 2009-12-03 University Of Massachusetts Type iii secretion inhibitors, analogs and uses thereof
TWI518076B (en) 2008-04-09 2016-01-21 杜邦股份有限公司 Method for preparing heterocyclic compound
EP2218464A1 (en) * 2009-02-11 2010-08-18 Technische Universität München Compounds for non-invasive measurement of aggregates of amyloid peptides
WO2011041293A1 (en) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
RU2608611C2 (en) 2009-11-05 2017-01-23 Юниверсити Оф Нотр Дам Дю Лак Imidazo[1,2-a]pyridine compounds, synthesis thereof and methods of using same
RS53176B (en) 2010-02-03 2014-06-30 Takeda Pharmaceutical Company Limited Apoptosis signal-regulating kinase 1 inhibitors
HUE028501T2 (en) 2010-05-27 2016-12-28 Du Pont Crystalline form of 4-[5 - [3 -chloro-5 -(trifluoromethyl)phenyl] -4,5 -dihydro-5 -(trifluoromethyl)-3 - isoxazolyl]-n-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1- naphthalenecarboxamide
RU2538964C1 (en) * 2010-12-17 2015-01-10 Мицубиси Танабе Фарма Корпорейшн Compound with successive aricyclic structure, possessing activity of inhibiting acycloenzyme a diacylglycerolacyltransferase (dgat1)
PE20142400A1 (en) * 2012-04-27 2015-02-04 Glaxo Group Ltd NOVEL COMPOUNDS
JP5721032B2 (en) * 2012-06-15 2015-05-20 田辺三菱製薬株式会社 Pharmaceutical composition
ES2690315T3 (en) 2012-06-15 2018-11-20 Mitsubishi Tanabe Pharma Corporation Imidazole and triazole compounds as DGAT-1 inhibitors
MX2018003294A (en) 2015-09-17 2019-04-25 J Miller Marvin Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection.
KR101910586B1 (en) 2017-03-03 2018-10-23 한국화학연구원 2-phenylimidazo[1,2-a]pyridine derivatives substituted with heteroaryl, preparation method thereof, and pharmaceutical composition for use in preventing or treating Glucagon-like peptide 1 Receptor activity related diseases containing the same as an active ingredient
CN110256382A (en) * 2019-06-06 2019-09-20 武汉药明康德新药开发有限公司 A kind of synthetic method of 2- (5- methyl benzofuran -2- base) benzonitrile
KR102514860B1 (en) * 2020-12-01 2023-03-29 한국과학기술연구원 Biphenyl pyrrolidine and biphenyl dihydroimidazole derivatives for inhibiting activity of 5-HT7 serotonin receptor and pharmaceutical composition comprising the same as an active ingredient

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1229652A (en) * 1968-03-20 1971-04-28
US3852303A (en) * 1969-03-05 1974-12-03 Sandoz Ag PROCESS FOR IMIDAZO{8 2,1-a{9 ISOINDOLES AND INTERMEDIATES
GB1322339A (en) * 1970-03-10 1973-07-04 American Home Prod Imidazoline derivatives
DE2219841A1 (en) * 1972-04-22 1973-10-25 Basf Ag PROCESS FOR THE PREPARATION OF 2- (OALKYLTHIOPHENYL) -1,3-DIAZACYCLOALKENHYDROHALOGENIDES
US3931218A (en) * 1973-02-14 1976-01-06 American Home Products Corporation 2-(N-alkyl-2-imidazolin-2-yl)benzophenones and process for their preparation
DK104382A (en) * 1981-03-11 1982-09-12 Wellcome Found PROCEDURE FOR PREPARING SUBSTITUTED BIPHENYL COMPOUNDS
US5210206A (en) * 1990-09-10 1993-05-11 Abbott Laboratories 1,3-oxazolyl substituted biphenyl
CA2128014A1 (en) * 1992-12-07 1994-06-23 Toshikazu Shimizu Process for the preparation of imidazopyridine derivatives and intermediates
DE69414348T2 (en) * 1993-06-18 1999-05-12 Otsuka Pharmaceutical Co., Ltd., Tokio/Tokyo FLUORENEON DERIVATIVES, METHOD FOR THEIR PRODUCTION AND RESTORATION AND PROTECTIVE AGENTS FOR CENTRAL AND PERIPHERAL NERVOUS DEGENERATIONS
IL114670A0 (en) * 1994-08-05 1995-11-27 Fujisawa Pharmaceutical Co Guanidine derivatives pharmaceutical compositions containing the same and processes for the preparation thereof
IL115875A (en) * 1994-11-14 2000-12-06 Univ Georgia State Res Found Methods of inhibiting pneumocystis carinii pneumonia giardia lamblia and cryptosporidium parvum in an animal subject and compounds useful therefor
ZA973848B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
FR2756560A1 (en) * 1996-12-04 1998-06-05 Adir NOVEL IMIDAZOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
WO2000078726A1 (en) 2000-12-28
GB2351081A (en) 2000-12-20
AU5722800A (en) 2001-01-09

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)