GB9816583D0 - Nucleic acid carrier - Google Patents

Nucleic acid carrier

Info

Publication number
GB9816583D0
GB9816583D0 GBGB9816583.0A GB9816583A GB9816583D0 GB 9816583 D0 GB9816583 D0 GB 9816583D0 GB 9816583 A GB9816583 A GB 9816583A GB 9816583 D0 GB9816583 D0 GB 9816583D0
Authority
GB
United Kingdom
Prior art keywords
nucleic acid
acid carrier
organism
red blood
blood cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB9816583.0A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ulster University
Original Assignee
Ulster University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ulster University filed Critical Ulster University
Priority to GBGB9816583.0A priority Critical patent/GB9816583D0/en
Publication of GB9816583D0 publication Critical patent/GB9816583D0/en
Priority to AU51789/99A priority patent/AU5178999A/en
Priority to GB0017761A priority patent/GB2350060A/en
Priority to PCT/GB1999/002490 priority patent/WO2000007630A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A61K9/5068—Cell membranes or bacterial membranes enclosing drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis

Abstract

The invention relates to a method for delivering a nucleic acid to a target site in an organism, comprising the steps of: a) loading a red blood cell with a nucleic acid; b) introducing into the organism the red blood cell loaded with the nucleic acid; and c) causing the nucleic acid to be released from the red blood cell at the target site in the organism.
GBGB9816583.0A 1998-07-31 1998-07-31 Nucleic acid carrier Ceased GB9816583D0 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
GBGB9816583.0A GB9816583D0 (en) 1998-07-31 1998-07-31 Nucleic acid carrier
AU51789/99A AU5178999A (en) 1998-07-31 1999-07-30 Nucleic acid delivery
GB0017761A GB2350060A (en) 1998-07-31 1999-07-30 Nucleic acid delivery
PCT/GB1999/002490 WO2000007630A1 (en) 1998-07-31 1999-07-30 Nucleic acid delivery

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9816583.0A GB9816583D0 (en) 1998-07-31 1998-07-31 Nucleic acid carrier

Publications (1)

Publication Number Publication Date
GB9816583D0 true GB9816583D0 (en) 1998-09-30

Family

ID=10836418

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB9816583.0A Ceased GB9816583D0 (en) 1998-07-31 1998-07-31 Nucleic acid carrier
GB0017761A Withdrawn GB2350060A (en) 1998-07-31 1999-07-30 Nucleic acid delivery

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB0017761A Withdrawn GB2350060A (en) 1998-07-31 1999-07-30 Nucleic acid delivery

Country Status (3)

Country Link
AU (1) AU5178999A (en)
GB (2) GB9816583D0 (en)
WO (1) WO2000007630A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001272670A1 (en) * 2000-07-24 2002-02-05 Gendel Limited Polypeptide delivery II-2
WO2002057436A2 (en) * 2001-01-19 2002-07-25 Gendel Limited Red blood cell from a transgenic animal as vehicle for polypeptide delivery
BR112014009346B1 (en) 2011-10-17 2020-09-15 Massachusetts Institute Of Technology INTRACELLULAR DELIVERY
US10124336B2 (en) 2013-08-16 2018-11-13 Massachusetts Institute Of Technology Selective delivery of material to cells
JP2017533702A (en) 2014-10-31 2017-11-16 マサチューセッツ インスティテュート オブ テクノロジー Delivery of biomolecules to immune cells
EP3218492A4 (en) 2014-11-14 2018-10-10 Massachusetts Institute Of Technology Disruption and field enabled delivery of compounds and compositions into cells
CN107250373A (en) 2015-01-12 2017-10-13 麻省理工学院 The gene editing realized is delivered by microfluid
CA2988996A1 (en) * 2015-07-09 2017-01-12 Massachusetts Institute Of Technology Delivery of materials to anucleate cells
WO2017041051A1 (en) 2015-09-04 2017-03-09 Sqz Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931276A (en) * 1987-10-30 1990-06-05 Franco Robert S Method for introducing desired agents into red blood cells
AU6505690A (en) * 1989-09-26 1991-04-28 Richard R Behringer Erythroid-specific gene expression system
CA2150617C (en) * 1995-02-07 2001-10-30 Universite Laval Nanoerythrosome as bioactive agent carrier

Also Published As

Publication number Publication date
AU5178999A (en) 2000-02-28
WO2000007630A1 (en) 2000-02-17
GB2350060A (en) 2000-11-22
GB0017761D0 (en) 2000-09-06

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)